Luisa Demarchi
@luisadema.bsky.social
Postdoc in @Kundakoviclab.bsky.social
If you’re at #ACNP2026, come say hi! 👋
I’ll be presenting the poster TH288 on the inactive X chromosome as a hormone-responsive driver of female brain plasticity 🧠🧬 @kundakoviclab.bsky.social
I’ll be presenting the poster TH288 on the inactive X chromosome as a hormone-responsive driver of female brain plasticity 🧠🧬 @kundakoviclab.bsky.social
January 15, 2026 at 2:45 PM
If you’re at #ACNP2026, come say hi! 👋
I’ll be presenting the poster TH288 on the inactive X chromosome as a hormone-responsive driver of female brain plasticity 🧠🧬 @kundakoviclab.bsky.social
I’ll be presenting the poster TH288 on the inactive X chromosome as a hormone-responsive driver of female brain plasticity 🧠🧬 @kundakoviclab.bsky.social
Reposted by Luisa Demarchi
#ACNP2026: Don't miss our symposium on Mon 3-5PM in Poseidon III-IV:
"How Brain Estrogen Levels, Receptors & Signaling Govern Behaviors Across Sexes: Genes, Circuits, Synapses"
w/ @polymniag.bsky.social @neurohoke.bsky.social
@neurolg.bsky.social & myself. Looking forward! @acnporg.bsky.social
"How Brain Estrogen Levels, Receptors & Signaling Govern Behaviors Across Sexes: Genes, Circuits, Synapses"
w/ @polymniag.bsky.social @neurohoke.bsky.social
@neurolg.bsky.social & myself. Looking forward! @acnporg.bsky.social
January 12, 2026 at 5:00 AM
#ACNP2026: Don't miss our symposium on Mon 3-5PM in Poseidon III-IV:
"How Brain Estrogen Levels, Receptors & Signaling Govern Behaviors Across Sexes: Genes, Circuits, Synapses"
w/ @polymniag.bsky.social @neurohoke.bsky.social
@neurolg.bsky.social & myself. Looking forward! @acnporg.bsky.social
"How Brain Estrogen Levels, Receptors & Signaling Govern Behaviors Across Sexes: Genes, Circuits, Synapses"
w/ @polymniag.bsky.social @neurohoke.bsky.social
@neurolg.bsky.social & myself. Looking forward! @acnporg.bsky.social
Reposted by Luisa Demarchi
Extremely excited & proud to share our new preprint - we provide for the first time a single cell map of the mouse brain across sex, the estrous cycle, and peripartum! Data are 🔥 👇
"Single-cell map of the female brain across reproductive transitions"
www.biorxiv.org/content/10.6...
"Single-cell map of the female brain across reproductive transitions"
www.biorxiv.org/content/10.6...
January 4, 2026 at 8:45 PM
Extremely excited & proud to share our new preprint - we provide for the first time a single cell map of the mouse brain across sex, the estrous cycle, and peripartum! Data are 🔥 👇
"Single-cell map of the female brain across reproductive transitions"
www.biorxiv.org/content/10.6...
"Single-cell map of the female brain across reproductive transitions"
www.biorxiv.org/content/10.6...
Reposted by Luisa Demarchi
Ending 2025 w/ our new paper @natcomms.nature.com which shows that the immediate early gene Egr1 induces sex-dependent changes in ventral hippocampal (vHIP) structure and in anxiety- & depression-related behavior, via direct regulation of chromatin structure 🧵👇 1/
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Egr1 is a sex-dependent regulator of neuronal chromatin, structural plasticity, and behaviour - Nature Communications
Molecular drivers of sex-specific brain plasticity are unknown. Here, authors show estrogen-driven Egr1 controls chromatin accessibility sex-dependently, driving gene expression, structural plasticity...
www.nature.com
December 31, 2025 at 8:57 PM
Ending 2025 w/ our new paper @natcomms.nature.com which shows that the immediate early gene Egr1 induces sex-dependent changes in ventral hippocampal (vHIP) structure and in anxiety- & depression-related behavior, via direct regulation of chromatin structure 🧵👇 1/
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Luisa Demarchi
Goodbye San Diego! Thank you @sfn.org for another great meeting & exciting science! In the future, I hope to see more progressive work on sex/gender & critical #WomensHealth - related factors -ovarian cycle, menopause, pregnancy- featured in lectures & symposia! See you next year! #SfN25
November 19, 2025 at 10:01 PM
Goodbye San Diego! Thank you @sfn.org for another great meeting & exciting science! In the future, I hope to see more progressive work on sex/gender & critical #WomensHealth - related factors -ovarian cycle, menopause, pregnancy- featured in lectures & symposia! See you next year! #SfN25
Reposted by Luisa Demarchi
Visit our posters on Sat, Sun & Weds @sfn.org ! @luisadema.bsky.social & @lailaouldibbat.bsky.social will present at #TPDA session too. I'll be around for all posters - let's chat about single-cell studies across the cycle, peripartum, OVX.. & the cool dynamics of the X chrom! See you there! #SfN25
November 15, 2025 at 2:03 AM
Visit our posters on Sat, Sun & Weds @sfn.org ! @luisadema.bsky.social & @lailaouldibbat.bsky.social will present at #TPDA session too. I'll be around for all posters - let's chat about single-cell studies across the cycle, peripartum, OVX.. & the cool dynamics of the X chrom! See you there! #SfN25
Reposted by Luisa Demarchi
Excited to have my piece on perimenopause published @thetransmitter.bsky.social
"Perimenopause: An important—and understudied—transition for the brain"
We need more studies & better education -we need this to be mainstream- knowledge is power! #WomensHealth
www.thetransmitter.org/sex-hormones...
"Perimenopause: An important—and understudied—transition for the brain"
We need more studies & better education -we need this to be mainstream- knowledge is power! #WomensHealth
www.thetransmitter.org/sex-hormones...
Perimenopause: An understudied transition for the brain
We know little about the mechanisms underlying well-known perimenopause symptoms in the brain. More research—in animals and humans—is essential.
www.thetransmitter.org
November 12, 2025 at 8:14 AM
Excited to have my piece on perimenopause published @thetransmitter.bsky.social
"Perimenopause: An important—and understudied—transition for the brain"
We need more studies & better education -we need this to be mainstream- knowledge is power! #WomensHealth
www.thetransmitter.org/sex-hormones...
"Perimenopause: An important—and understudied—transition for the brain"
We need more studies & better education -we need this to be mainstream- knowledge is power! #WomensHealth
www.thetransmitter.org/sex-hormones...
Reposted by Luisa Demarchi
Check out this nice story from @fordham.edu News on our work on #menopause transition recently published in Molecular Psychiatry & funded by the NIH. Knowledge is power! #WomensHealth 🔥
"Professor Leads Groundbreaking Study on Menopause-Mental Health Connection”
now.fordham.edu/university-n...
"Professor Leads Groundbreaking Study on Menopause-Mental Health Connection”
now.fordham.edu/university-n...
Professor Leads Groundbreaking Study on Menopause-Mental Health Connection
A biology professor is examining the links between menopause and depression, anxiety, and other mental illnesses, building on a pioneering study she and her team just published.
now.fordham.edu
October 3, 2025 at 2:10 AM
Check out this nice story from @fordham.edu News on our work on #menopause transition recently published in Molecular Psychiatry & funded by the NIH. Knowledge is power! #WomensHealth 🔥
"Professor Leads Groundbreaking Study on Menopause-Mental Health Connection”
now.fordham.edu/university-n...
"Professor Leads Groundbreaking Study on Menopause-Mental Health Connection”
now.fordham.edu/university-n...
Reposted by Luisa Demarchi
Big lab celebration: my 10 year anniversary @fordham.edu ; papers accepted @natcomms.nature.com Mol. Psychiatry @npp-journal.bsky.social ; @luisadema.bsky.social & @lailaouldibbat.bsky.social won #TPDA @sfn.org ; new postdoc @bruzzone-sep.bsky.social ; w/ Devin Rocks 🍾 Killing it - so proud! 🔥
September 19, 2025 at 11:24 PM
Big lab celebration: my 10 year anniversary @fordham.edu ; papers accepted @natcomms.nature.com Mol. Psychiatry @npp-journal.bsky.social ; @luisadema.bsky.social & @lailaouldibbat.bsky.social won #TPDA @sfn.org ; new postdoc @bruzzone-sep.bsky.social ; w/ Devin Rocks 🍾 Killing it - so proud! 🔥
Reposted by Luisa Demarchi
A new 🔥 Hot Topic 🔥 from @kundakoviclab.bsky.social is out now in @npp-journal.bsky.social
Thrilled to share our Hot Topics article just published @npp-journal.bsky.social :
"Leveraging high-resolution brain imaging & (epi)genomic approaches to improve women’s mental health"
Always huge pleasure to work w/ @cogneuroend.bsky.social on revolutionizing #WomensMentalHealth 🔥
rdcu.be/eCy6i
"Leveraging high-resolution brain imaging & (epi)genomic approaches to improve women’s mental health"
Always huge pleasure to work w/ @cogneuroend.bsky.social on revolutionizing #WomensMentalHealth 🔥
rdcu.be/eCy6i
Leveraging high-resolution brain imaging and (epi)genomic approaches to improve women’s mental health
Neuropsychopharmacology - Leveraging high-resolution brain imaging and (epi)genomic approaches to improve women’s mental health
rdcu.be
August 27, 2025 at 7:37 PM
A new 🔥 Hot Topic 🔥 from @kundakoviclab.bsky.social is out now in @npp-journal.bsky.social
Reposted by Luisa Demarchi
Amazing day in the lab today... we first got our menopause biomarker paper accepted in Molecular Psychiatry and then... BOTH @lailaouldibbat.bsky.social and @luisadema.bsky.social received the Trainee Professional Development Award #TPDA from @sfn.org . So proud of the lab and my lab members! 🔥
a woman is sitting on a couch with her legs crossed
ALT: a woman is sitting on a couch with her legs crossed
media.tenor.com
August 15, 2025 at 9:57 PM
Amazing day in the lab today... we first got our menopause biomarker paper accepted in Molecular Psychiatry and then... BOTH @lailaouldibbat.bsky.social and @luisadema.bsky.social received the Trainee Professional Development Award #TPDA from @sfn.org . So proud of the lab and my lab members! 🔥
Reposted by Luisa Demarchi
Excited to share this huge team effort collaboration supervised by Stephanie Page in Translational Neuroscience @lieberinstitute.bsky.social and @stephaniehicks.bsky.social @jhubiostat.bsky.social to generate a spatio-molecular resource of the hippocampus in human 🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus - Nature Neuroscience
The topographical organization of cells in the hippocampus reflects its ability to regulate mood and cognition. Here the authors generate a spatially resolved gene expression map in the human hippocam...
www.nature.com
July 30, 2025 at 8:51 PM
Excited to share this huge team effort collaboration supervised by Stephanie Page in Translational Neuroscience @lieberinstitute.bsky.social and @stephaniehicks.bsky.social @jhubiostat.bsky.social to generate a spatio-molecular resource of the hippocampus in human 🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Luisa Demarchi
Enjoying the gala dinner and the beautiful city of Bordeaux last night, w/ @luisadema.bsky.social @jordanmarrocco.bsky.social @cate-cholamine.bsky.social @bohaceklab.bsky.social @ebbsociety.bsky.social #EBBS2025
July 1, 2025 at 12:19 PM
Enjoying the gala dinner and the beautiful city of Bordeaux last night, w/ @luisadema.bsky.social @jordanmarrocco.bsky.social @cate-cholamine.bsky.social @bohaceklab.bsky.social @ebbsociety.bsky.social #EBBS2025
Reposted by Luisa Demarchi
Welcome party #EBBS2025 @ebbsociety.bsky.social so happy to catch up with my former PhD student @luisadema.bsky.social along with my current @annika-koeck.bsky.social
June 29, 2025 at 5:32 AM
Welcome party #EBBS2025 @ebbsociety.bsky.social so happy to catch up with my former PhD student @luisadema.bsky.social along with my current @annika-koeck.bsky.social
Reposted by Luisa Demarchi
The end of the semester lab lunch in Zero Otto Nove... Saying goodbye to our students Anaya, Fletcher, and Liz... with a visit from the lab alumnus Eric.. Always having a great time with these wonderful young people! ❤️ w/ @luisadema.bsky.social @lailaouldibbat.bsky.social
May 16, 2025 at 3:02 AM
The end of the semester lab lunch in Zero Otto Nove... Saying goodbye to our students Anaya, Fletcher, and Liz... with a visit from the lab alumnus Eric.. Always having a great time with these wonderful young people! ❤️ w/ @luisadema.bsky.social @lailaouldibbat.bsky.social
Reposted by Luisa Demarchi
My lab is hiring 2 postdocs on an NIH-funded grant characterizing molecular & cellular changes in the human brain across menopausal transition. Other neuroepigenomics projects are also available. We plan to hire a wet lab scientist and a bioinformatician. Please RT!
kundakoviclab.com
More info 👇
kundakoviclab.com
More info 👇
March 11, 2025 at 6:32 AM
My lab is hiring 2 postdocs on an NIH-funded grant characterizing molecular & cellular changes in the human brain across menopausal transition. Other neuroepigenomics projects are also available. We plan to hire a wet lab scientist and a bioinformatician. Please RT!
kundakoviclab.com
More info 👇
kundakoviclab.com
More info 👇
Reposted by Luisa Demarchi
Had a wonderful evening celebrating my promotion to full professor with my lab members & alumni. Thank you all for shining so brightly, for the fantastic work that you do, and for being part of this amazing journey! ❤️ @luisadema.bsky.social @lailaouldibbat.bsky.social
March 6, 2025 at 4:34 AM
Had a wonderful evening celebrating my promotion to full professor with my lab members & alumni. Thank you all for shining so brightly, for the fantastic work that you do, and for being part of this amazing journey! ❤️ @luisadema.bsky.social @lailaouldibbat.bsky.social
Very happy to share that the last data from my PhD is now available as a preprint! Huge thanks to @olibosch.bsky.social @alicesanson.bsky.social and all my former colleagues for their support throughout this journey.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
February 18, 2025 at 6:42 PM
Very happy to share that the last data from my PhD is now available as a preprint! Huge thanks to @olibosch.bsky.social @alicesanson.bsky.social and all my former colleagues for their support throughout this journey.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Luisa Demarchi
Excited to share Laila’s @lailaouldibbat.bsky.social first first-author paper & the very first “metabolic” paper from the lab just published @ Hormones & Behavior:
"The role of ovarian hormone dynamics in metabolic phenotype and gene expression in female mice"
www.sciencedirect.com/science/arti...
"The role of ovarian hormone dynamics in metabolic phenotype and gene expression in female mice"
www.sciencedirect.com/science/arti...
The role of ovarian hormone dynamics in metabolic phenotype and gene expression in female mice
Ovarian hormones, particularly estradiol, play an important role in the regulation of metabolic function including in food intake, thermogenesis, acti…
www.sciencedirect.com
February 12, 2025 at 7:41 AM
Excited to share Laila’s @lailaouldibbat.bsky.social first first-author paper & the very first “metabolic” paper from the lab just published @ Hormones & Behavior:
"The role of ovarian hormone dynamics in metabolic phenotype and gene expression in female mice"
www.sciencedirect.com/science/arti...
"The role of ovarian hormone dynamics in metabolic phenotype and gene expression in female mice"
www.sciencedirect.com/science/arti...
Reposted by Luisa Demarchi
Thrilled to share my perspective in "The Transmitter" @thetransmitter.bsky.social on how to study the influence of "sex" and "gender" in the brain in a scientifically accurate and socially responsible manner:
"Revisiting sex and gender in the brain"
www.thetransmitter.org/sex-differen...
"Revisiting sex and gender in the brain"
www.thetransmitter.org/sex-differen...
Revisiting sex and gender in the brain
To conduct scientifically accurate and socially responsible research, think of “sex” as a complex, multifactorial and context-dependent variable.
www.thetransmitter.org
January 28, 2025 at 6:29 AM
Thrilled to share my perspective in "The Transmitter" @thetransmitter.bsky.social on how to study the influence of "sex" and "gender" in the brain in a scientifically accurate and socially responsible manner:
"Revisiting sex and gender in the brain"
www.thetransmitter.org/sex-differen...
"Revisiting sex and gender in the brain"
www.thetransmitter.org/sex-differen...
Reposted by Luisa Demarchi
After 5 years of data collection (179 first-time mothers + controls), the first bemother.eu/en/ paper is out! We uncovered a U-shaped trajectory in maternal GM volume, resolving a long-standing puzzle in the maternal brain field. www.nature.com/articles/s41...
January 17, 2025 at 5:54 PM
After 5 years of data collection (179 first-time mothers + controls), the first bemother.eu/en/ paper is out! We uncovered a U-shaped trajectory in maternal GM volume, resolving a long-standing puzzle in the maternal brain field. www.nature.com/articles/s41...
Reposted by Luisa Demarchi
Just received a wonderful Christmas gift from the NIH! $2.76M to study molecular & cellular changes in the human brain across the menopausal transition! 🎉 Am icredibly excited! We will be hiring 2 postdocs — come join us in NYC for some cool science, as we transform women’s mental health research!!
December 18, 2024 at 7:22 PM
Just received a wonderful Christmas gift from the NIH! $2.76M to study molecular & cellular changes in the human brain across the menopausal transition! 🎉 Am icredibly excited! We will be hiring 2 postdocs — come join us in NYC for some cool science, as we transform women’s mental health research!!
Reposted by Luisa Demarchi
New open access paper out in Neuropharmacology!
@alicesanson.bsky.social shares another piece of the puzzle about the role of the #CRF and #oxytocin systems in the nucleus accumbens shell (NacSh) in the postpartum period. You can read it here: doi.org/10.1016/j.ne...
@alicesanson.bsky.social shares another piece of the puzzle about the role of the #CRF and #oxytocin systems in the nucleus accumbens shell (NacSh) in the postpartum period. You can read it here: doi.org/10.1016/j.ne...
Redirecting
doi.org
December 17, 2024 at 9:05 AM
New open access paper out in Neuropharmacology!
@alicesanson.bsky.social shares another piece of the puzzle about the role of the #CRF and #oxytocin systems in the nucleus accumbens shell (NacSh) in the postpartum period. You can read it here: doi.org/10.1016/j.ne...
@alicesanson.bsky.social shares another piece of the puzzle about the role of the #CRF and #oxytocin systems in the nucleus accumbens shell (NacSh) in the postpartum period. You can read it here: doi.org/10.1016/j.ne...
Reposted by Luisa Demarchi
Lab lunch today to welcome our new postdoc Ana Milosevic and to celebrate many recent B-days and accomplishments in the lab. Very proud of this amazing group of young scientists. Stay tuned for several cool papers coming from the lab soon! 🔥 w/ @luisadema.bsky.social
December 5, 2024 at 2:33 AM
Lab lunch today to welcome our new postdoc Ana Milosevic and to celebrate many recent B-days and accomplishments in the lab. Very proud of this amazing group of young scientists. Stay tuned for several cool papers coming from the lab soon! 🔥 w/ @luisadema.bsky.social
#OlafurEliasson exhibition in NYC. If you want to awaken your senses, this is the perfect place ✨
December 1, 2024 at 5:09 AM
#OlafurEliasson exhibition in NYC. If you want to awaken your senses, this is the perfect place ✨