Lindsay Hohsfield, Ph.D.
lindsayhohsfield.bsky.social
Lindsay Hohsfield, Ph.D.
@lindsayhohsfield.bsky.social
Neuroscientist. Alzheimer’s researcher. CNS myeloid cell enthusiast in Kim Green’s lab @UCI. Founder of Youngtimers. Advocate for rare early onset Alzheimer’s. Toddler and husky mom.
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Excited to share our new paper out in @cp-neuron.bsky.social today! We discovered the neuroanatomical route that myeloid cells use to enter the brain parenchyma. Check it out here: authors.elsevier.com/c/1lCYs3BtfH...
Excited to share our new paper out in @cp-neuron.bsky.social today! We discovered the neuroanatomical route that myeloid cells use to enter the brain parenchyma. Check it out here: authors.elsevier.com/c/1lCYs3BtfH...
June 3, 2025 at 4:00 PM
Reposted by Lindsay Hohsfield, Ph.D.
Identification of the velum interpositum as a meningeal-CNS route for myeloid cell trafficking into the brain: @cp-neuron.bsky.social www.cell.com/neuron/fullt...
June 3, 2025 at 2:49 PM
Reposted by Lindsay Hohsfield, Ph.D.
"… we are in a propitious position to accurately and precisely determine who is at high risk of developing #AlzheimersDisease years before signs of even mild cognitive deficit," writes @erictopol.bsky.social‬ in a new #ScienceExpertVoices article.

Read more: scim.ag/4koj8F5
June 3, 2025 at 3:07 PM
Hi Bluesky! I’m Lindsay Hohsfield and I work as an Associate Researcher at the University of California, Irvine in Kim Green’s lab. I study #microglia and #Alzheimer’s disease. I also founded Youngtimers, a nonprofit for rare young onset Alzheimer’s disease.
December 4, 2024 at 6:59 AM
Reposted by Lindsay Hohsfield, Ph.D.
Haploinsufficiency at the CX3CR1 locus of hematopoietic stem cells favors the appearance of microglia-like cells in the central nervous system of transplant recipients

www.nature.com/articles/s41...
Haploinsufficiency at the CX3CR1 locus of hematopoietic stem cells favors the appearance of microglia-like cells in the central nervous system of transplant recipients - Nature Communications
In this paper, a CRISPR-based gene addition strategy at the CX3CR1 locus of human hematopoietic stem cells is proposed to efficiently generate microglia engineered for the regulated expression of ther...
www.nature.com
November 26, 2024 at 12:13 AM