Lena Amend
@lenaamend.bsky.social
Microbiome researcher, host-microbe interactions, bacterial cross-feeding 🧫
Postdoc at University Würzburg
Postdoc at University Würzburg
Reposted by Lena Amend
Congrats to Ann-Sophie Rüttiger who successfully defended her PhD this week! 🎓
She focused on global RNA-binding proteins in Bacteroides—bacteria lacking Hfq, ProQ, CsrA, Khp—culminating in the discovery of a post-transcriptional network governed by RbpB (www.nature.com/articles/s41467-024-55383-8).
She focused on global RNA-binding proteins in Bacteroides—bacteria lacking Hfq, ProQ, CsrA, Khp—culminating in the discovery of a post-transcriptional network governed by RbpB (www.nature.com/articles/s41467-024-55383-8).
September 25, 2025 at 10:06 AM
Congrats to Ann-Sophie Rüttiger who successfully defended her PhD this week! 🎓
She focused on global RNA-binding proteins in Bacteroides—bacteria lacking Hfq, ProQ, CsrA, Khp—culminating in the discovery of a post-transcriptional network governed by RbpB (www.nature.com/articles/s41467-024-55383-8).
She focused on global RNA-binding proteins in Bacteroides—bacteria lacking Hfq, ProQ, CsrA, Khp—culminating in the discovery of a post-transcriptional network governed by RbpB (www.nature.com/articles/s41467-024-55383-8).
Reposted by Lena Amend
Latest preprint from the lab: doi.org/10.1101/2025...
In this study lead by @lenaamend.bsky.social from the group, we explore carbon cross-feeding between a gut commensal and an enteropathogen. Can we counter infection by cutting sugar supply to pathogens?
In this study lead by @lenaamend.bsky.social from the group, we explore carbon cross-feeding between a gut commensal and an enteropathogen. Can we counter infection by cutting sugar supply to pathogens?
Ablation of polysaccharide breakdown in Bacteroides thetaiotaomicron prevents cross-feeding and growth of Salmonella Typhimurium in the mouse gut
Pathogens invading the intestine compete for nutrients with the resident microbiota. However, there is evidence that commensal members of the gut also provide nutritional resources to enteropathogens ...
doi.org
August 17, 2025 at 6:13 AM
Latest preprint from the lab: doi.org/10.1101/2025...
In this study lead by @lenaamend.bsky.social from the group, we explore carbon cross-feeding between a gut commensal and an enteropathogen. Can we counter infection by cutting sugar supply to pathogens?
In this study lead by @lenaamend.bsky.social from the group, we explore carbon cross-feeding between a gut commensal and an enteropathogen. Can we counter infection by cutting sugar supply to pathogens?
Reposted by Lena Amend
Ablation of polysaccharide breakdown in Bacteroides thetaiotaomicron prevents cross-feeding and growth of Salmonella Typhimurium in the mouse gut https://www.biorxiv.org/content/10.1101/2025.08.08.669261v1
August 9, 2025 at 4:18 AM
Ablation of polysaccharide breakdown in Bacteroides thetaiotaomicron prevents cross-feeding and growth of Salmonella Typhimurium in the mouse gut https://www.biorxiv.org/content/10.1101/2025.08.08.669261v1
Reposted by Lena Amend
Very honored that our recent study on Bacteroides morphotypes was spotlighted 🔦 in Trends in Microbiology by Eric Martens & Qinnan Yang: www.cell.com/trends/micro....
Low biomass bacterial transcriptomics takes shape
Bornet et al. apply a low-input bacterial RNA-seq pipeline to transcriptionally profile
small, medium, and large cell populations of the human gut symbiont Bacteroides thetaiotaomicron
separated by fl...
www.cell.com
July 8, 2025 at 10:59 AM
Very honored that our recent study on Bacteroides morphotypes was spotlighted 🔦 in Trends in Microbiology by Eric Martens & Qinnan Yang: www.cell.com/trends/micro....
Reposted by Lena Amend
Our latest: www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1. Links Bacteroides cell size w/ gene expression. Protocol works even for single cells. 🦠
Shoutout to @elisebor.bsky.social, @emmanuel-saliba.bsky.social, @lbarquist.bsky.social, @jorg-vogel-lab.bsky.social, Till Strowig & KC Huang.
Shoutout to @elisebor.bsky.social, @emmanuel-saliba.bsky.social, @lbarquist.bsky.social, @jorg-vogel-lab.bsky.social, Till Strowig & KC Huang.
Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium
Bornet et al. investigate the morphological heterogeneity of Bacteroides thetaiotaomicron
cells observed both in laboratory culture and inside the mammalian GI tract. The authors
show that cell size i...
www.cell.com
June 17, 2025 at 7:11 PM
Our latest: www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1. Links Bacteroides cell size w/ gene expression. Protocol works even for single cells. 🦠
Shoutout to @elisebor.bsky.social, @emmanuel-saliba.bsky.social, @lbarquist.bsky.social, @jorg-vogel-lab.bsky.social, Till Strowig & KC Huang.
Shoutout to @elisebor.bsky.social, @emmanuel-saliba.bsky.social, @lbarquist.bsky.social, @jorg-vogel-lab.bsky.social, Till Strowig & KC Huang.
Reposted by Lena Amend
Some say, important sRNAs can be recognized by having their own “sponge” 🧽. Well, here comes InvS: a sponge of PinT (and vice versa). Congrats to @kooshapour.bsky.social and @ginlaca.bsky.social on their great work! doi.org/10.1101/2025...
Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT
Salmonella virulence chiefly relies upon two major pathogenicity islands, SPI-1 and SPI-2, which enable host cell invasion and intracellular survival, respectively. There has been increasing evidence ...
doi.org
April 10, 2025 at 8:06 AM
Some say, important sRNAs can be recognized by having their own “sponge” 🧽. Well, here comes InvS: a sponge of PinT (and vice versa). Congrats to @kooshapour.bsky.social and @ginlaca.bsky.social on their great work! doi.org/10.1101/2025...
Reposted by Lena Amend
Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT https://www.biorxiv.org/content/10.1101/2025.04.07.647523v1
April 8, 2025 at 4:20 AM
Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT https://www.biorxiv.org/content/10.1101/2025.04.07.647523v1
Honored to have been one of the selected scholarship awardees at the Keystone Symposium on the Human Microbiome in February 2025 in Banff, Canada.
I had an amazing time!
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
I had an amazing time!
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
Exciting developments from Banff, Canada, as we celebrate our award recipients at the joint meeting on Human Microbiome and Host-Microbe Co-Evolution in Human Health. Join us in applauding these exceptional scholarship winners!
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
March 1, 2025 at 12:10 AM
Honored to have been one of the selected scholarship awardees at the Keystone Symposium on the Human Microbiome in February 2025 in Banff, Canada.
I had an amazing time!
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
I had an amazing time!
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
Reposted by Lena Amend
Exciting developments from Banff, Canada, as we celebrate our award recipients at the joint meeting on Human Microbiome and Host-Microbe Co-Evolution in Human Health. Join us in applauding these exceptional scholarship winners!
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
February 21, 2025 at 6:28 PM
Exciting developments from Banff, Canada, as we celebrate our award recipients at the joint meeting on Human Microbiome and Host-Microbe Co-Evolution in Human Health. Join us in applauding these exceptional scholarship winners!
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia
#KSHumanMicro25 #KSHostMicrobe25 #keystonesymposia