Lara Curran
@laracurran.bsky.social
Cardiology Registrar | PhD CRTF Imperial NHLI | Cardiogenetics, imaging and machine-learning 🧬🫀|
So delighted to have been awarded 1st place for my PhD work at the @imperialnhli.bsky.social NHLI presentation day! Thank you to my brilliant supervisors - Prof Sanjay Prasad, @drdeclanoregan.bsky.social, @jamesware.bsky.social and @doctorpaz.bsky.social - for all their incredible support! 🫀🧬📈🥳
October 7, 2025 at 6:54 PM
So delighted to have been awarded 1st place for my PhD work at the @imperialnhli.bsky.social NHLI presentation day! Thank you to my brilliant supervisors - Prof Sanjay Prasad, @drdeclanoregan.bsky.social, @jamesware.bsky.social and @doctorpaz.bsky.social - for all their incredible support! 🫀🧬📈🥳
Reposted by Lara Curran
🚨Our double header on genetics of hypertrophic #cardiomyopathy out today in @naturegenet.bsky.social 🧬
📍GWAS www.nature.com/articles/s41...
📍polygenic scores www.nature.com/articles/s41...
A consortia effort by @jamesware.bsky.social Hugh Watkins @conniebezzina.bsky.social Rafik Tadros & Anuj Goel
📍GWAS www.nature.com/articles/s41...
📍polygenic scores www.nature.com/articles/s41...
A consortia effort by @jamesware.bsky.social Hugh Watkins @conniebezzina.bsky.social Rafik Tadros & Anuj Goel
www.nature.com
February 18, 2025 at 12:19 PM
🚨Our double header on genetics of hypertrophic #cardiomyopathy out today in @naturegenet.bsky.social 🧬
📍GWAS www.nature.com/articles/s41...
📍polygenic scores www.nature.com/articles/s41...
A consortia effort by @jamesware.bsky.social Hugh Watkins @conniebezzina.bsky.social Rafik Tadros & Anuj Goel
📍GWAS www.nature.com/articles/s41...
📍polygenic scores www.nature.com/articles/s41...
A consortia effort by @jamesware.bsky.social Hugh Watkins @conniebezzina.bsky.social Rafik Tadros & Anuj Goel
Reposted by Lara Curran
Q: How many genes should be tested for patients with hypertrophic cardiomyopathy? A: 29
Excited to share our latest: Re-Appraisal of HCM genes by our ClinGen Hereditary CVD Gene Curation Expert Panel out today in @jaccjournals.bsky.social
www.sciencedirect.com/science/arti...
Excited to share our latest: Re-Appraisal of HCM genes by our ClinGen Hereditary CVD Gene Curation Expert Panel out today in @jaccjournals.bsky.social
www.sciencedirect.com/science/arti...
Genes Associated With Hypertrophic Cardiomyopathy: A Reappraisal by the ClinGen Hereditary Cardiovascular Disease Gene Curation Expert Panel
Hypertrophic cardiomyopathy (HCM) is an inherited cardiac condition affecting ∼1 in 500 and exhibits marked genetic heterogeneity. Previously publishe…
www.sciencedirect.com
February 18, 2025 at 6:14 AM
Q: How many genes should be tested for patients with hypertrophic cardiomyopathy? A: 29
Excited to share our latest: Re-Appraisal of HCM genes by our ClinGen Hereditary CVD Gene Curation Expert Panel out today in @jaccjournals.bsky.social
www.sciencedirect.com/science/arti...
Excited to share our latest: Re-Appraisal of HCM genes by our ClinGen Hereditary CVD Gene Curation Expert Panel out today in @jaccjournals.bsky.social
www.sciencedirect.com/science/arti...
Reposted by Lara Curran
A vertical takeoff of life science with #AI LLLMs.
Publication of 10 new foundation models of Proteins, DNA, RNA, methylation, cells, and interactions, evolution, and design in the past couple of weeks!
Unprecedented progress, reviewed in the new Ground Truths
erictopol.substack.com/p/learning-t...
Publication of 10 new foundation models of Proteins, DNA, RNA, methylation, cells, and interactions, evolution, and design in the past couple of weeks!
Unprecedented progress, reviewed in the new Ground Truths
erictopol.substack.com/p/learning-t...
November 24, 2024 at 6:12 PM
A vertical takeoff of life science with #AI LLLMs.
Publication of 10 new foundation models of Proteins, DNA, RNA, methylation, cells, and interactions, evolution, and design in the past couple of weeks!
Unprecedented progress, reviewed in the new Ground Truths
erictopol.substack.com/p/learning-t...
Publication of 10 new foundation models of Proteins, DNA, RNA, methylation, cells, and interactions, evolution, and design in the past couple of weeks!
Unprecedented progress, reviewed in the new Ground Truths
erictopol.substack.com/p/learning-t...
Reposted by Lara Curran
🫀New paper by @kathrynmcgurk.bsky.social with @drdeclanoregan.bsky.social published today in
@natureportfolio.bsky.social describes the genetic architecture of myocardial trabeculae - the network of muscle fibres in the heart.🫀
@imperialnhli.bsky.social @thebhf.bsky.social
#Medsky #Cardiosky 🧪
@natureportfolio.bsky.social describes the genetic architecture of myocardial trabeculae - the network of muscle fibres in the heart.🫀
@imperialnhli.bsky.social @thebhf.bsky.social
#Medsky #Cardiosky 🧪
November 20, 2024 at 4:43 PM
🫀New paper by @kathrynmcgurk.bsky.social with @drdeclanoregan.bsky.social published today in
@natureportfolio.bsky.social describes the genetic architecture of myocardial trabeculae - the network of muscle fibres in the heart.🫀
@imperialnhli.bsky.social @thebhf.bsky.social
#Medsky #Cardiosky 🧪
@natureportfolio.bsky.social describes the genetic architecture of myocardial trabeculae - the network of muscle fibres in the heart.🫀
@imperialnhli.bsky.social @thebhf.bsky.social
#Medsky #Cardiosky 🧪
Reposted by Lara Curran
🧬 Our dilated #cardiomyopathy GWAS out today!
📍https://www.nature.com/articles/s41588-024-01952-y
All made possible with friends and collaborators from HERMES Consortium @alberthenry.bsky.social @tomlumbers.bsky.social @jamesware.bsky.social @mrc-lms.bsky.social @imperialnhli.bsky.social #BHF
🧵 👇
📍https://www.nature.com/articles/s41588-024-01952-y
All made possible with friends and collaborators from HERMES Consortium @alberthenry.bsky.social @tomlumbers.bsky.social @jamesware.bsky.social @mrc-lms.bsky.social @imperialnhli.bsky.social #BHF
🧵 👇
November 21, 2024 at 1:35 PM
🧬 Our dilated #cardiomyopathy GWAS out today!
📍https://www.nature.com/articles/s41588-024-01952-y
All made possible with friends and collaborators from HERMES Consortium @alberthenry.bsky.social @tomlumbers.bsky.social @jamesware.bsky.social @mrc-lms.bsky.social @imperialnhli.bsky.social #BHF
🧵 👇
📍https://www.nature.com/articles/s41588-024-01952-y
All made possible with friends and collaborators from HERMES Consortium @alberthenry.bsky.social @tomlumbers.bsky.social @jamesware.bsky.social @mrc-lms.bsky.social @imperialnhli.bsky.social #BHF
🧵 👇
Reposted by Lara Curran
—Please give me an A.I. that automatically detects, interprets all types of medical. images (scans, retina, endoscopy, skin) that I can interact with, can integrate data from other sources, saves a lot of time, and improves accuracy
—Sure, here it is
www.nature.com/articles/s41...
—Sure, here it is
www.nature.com/articles/s41...
November 20, 2024 at 2:28 PM
—Please give me an A.I. that automatically detects, interprets all types of medical. images (scans, retina, endoscopy, skin) that I can interact with, can integrate data from other sources, saves a lot of time, and improves accuracy
—Sure, here it is
www.nature.com/articles/s41...
—Sure, here it is
www.nature.com/articles/s41...
Reposted by Lara Curran
New paper out in @natureportfolio.bsky.social by @kathrynmcgurk.bsky.social on the genetic architecture of myocardial trabeculae. @mrc-lms.bsky.social www.nature.com/articles/s44...
Genetic and phenotypic architecture of human myocardial trabeculation - Nature Cardiovascular Research
The inner surface of the heart has a meshwork of muscles called trabeculae. McGurk et al. report the genetic regulation of these complex structures across common and rare variants, revealing pathways ...
www.nature.com
November 20, 2024 at 10:16 AM
New paper out in @natureportfolio.bsky.social by @kathrynmcgurk.bsky.social on the genetic architecture of myocardial trabeculae. @mrc-lms.bsky.social www.nature.com/articles/s44...
Reposted by Lara Curran
Exciting first bluesky post! We estimated trabecular complexity in 50,000 UK Biobank participants to identify influencing genetic, clinical, and lifestyle factors. Trabeculation progresses with cardiac diseases and changes can occur early in pathogenesis.
New paper out in @natureportfolio.bsky.social by @kathrynmcgurk.bsky.social on the genetic architecture of myocardial trabeculae. @mrc-lms.bsky.social www.nature.com/articles/s44...
Genetic and phenotypic architecture of human myocardial trabeculation - Nature Cardiovascular Research
The inner surface of the heart has a meshwork of muscles called trabeculae. McGurk et al. report the genetic regulation of these complex structures across common and rare variants, revealing pathways ...
www.nature.com
November 20, 2024 at 10:31 AM
Exciting first bluesky post! We estimated trabecular complexity in 50,000 UK Biobank participants to identify influencing genetic, clinical, and lifestyle factors. Trabeculation progresses with cardiac diseases and changes can occur early in pathogenesis.