Alastair Lamb
@lambalastair.bsky.social
Prostate Cancer @CancerResearchUK.org Clinician Scientist. Urologist. Robotics | #SPACE_Study PI | @TranslateTrial CI | @BJUIJournal.bsky.social SE pros/web | Views own. RT=endsmt
Pinned
V cool to be starting first proper day @QMBCI.bsky.social Charterhouse Sq! Thanks to Francesca C & Nitzan Rosenfeld for taking me on as Group Leader in Centre for Cancer Evolution🧬. And to Guys Urology for making it work🙏
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
Nice #LightningTalk from @maxbeesley.bsky.social as part of #PPCG 2025 meeting
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
November 13, 2025 at 12:37 PM
Nice #LightningTalk from @maxbeesley.bsky.social as part of #PPCG 2025 meeting
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
Real treat to hear Ros Eeles explain rationale for genetic risk in #ProstateCancer screening.
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
November 12, 2025 at 1:35 PM
Real treat to hear Ros Eeles explain rationale for genetic risk in #ProstateCancer screening.
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
Great work from @maxbeesley.bsky.social in his first #WhiteboardPresentation to assembled @qmbci.bsky.social #CEV!!
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
November 7, 2025 at 6:14 PM
Great work from @maxbeesley.bsky.social in his first #WhiteboardPresentation to assembled @qmbci.bsky.social #CEV!!
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
Great to be at @kingscollegelondon.bsky.social #SpatialBiology Day in Robens Suite atop #GuysTower
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
October 20, 2025 at 1:09 PM
Great to be at @kingscollegelondon.bsky.social #SpatialBiology Day in Robens Suite atop #GuysTower
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
Reposted by Alastair Lamb
New CRUK Post-doc position in our group. #mutationalorder #multiomics #cancer.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
October 6, 2025 at 10:55 AM
New CRUK Post-doc position in our group. #mutationalorder #multiomics #cancer.
my.corehr.com/pls/uoxrecru...
my.corehr.com/pls/uoxrecru...
Reposted by Alastair Lamb
We are looking for our next PhD student to join us 🤩 www.mcclellandlab.com to understand cancer radiation therapy's impact on DNA damage repair and chromosomal instability. Prestigious funding from CRUK RadNet. Please contact me informally - deadline 5th Nov! crukradnet.colcc.ac.uk/phd-students...
October 2, 2025 at 3:49 PM
We are looking for our next PhD student to join us 🤩 www.mcclellandlab.com to understand cancer radiation therapy's impact on DNA damage repair and chromosomal instability. Prestigious funding from CRUK RadNet. Please contact me informally - deadline 5th Nov! crukradnet.colcc.ac.uk/phd-students...
Really enjoyed 1st Faculty Retreat for @qmbci.bsky.social Centre for Cancer Evolution #CEV PIs
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
October 2, 2025 at 3:09 PM
Really enjoyed 1st Faculty Retreat for @qmbci.bsky.social Centre for Cancer Evolution #CEV PIs
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
Reposted by Alastair Lamb
Come and join us at the Barts Cancer Institute @qmbci.bsky.social ! Our medical school, part of Queen Mary University of London @qmulfmd.bsky.social is hiring 10 professors!! www.veredus.co.uk/job/job-747a/. Contact me for a chat if interested.
Professors x 10, Faculty of Medicine & Dentistry | Veredus
QUEEN MARY UNIVERSITY OF LONDON Professors x 10, Faculty of Medicine and Dentistry London Competitive Remuneration Package Queen Mary University of London seeks up to 10 world-leading translational re...
www.veredus.co.uk
October 1, 2025 at 7:34 AM
Come and join us at the Barts Cancer Institute @qmbci.bsky.social ! Our medical school, part of Queen Mary University of London @qmulfmd.bsky.social is hiring 10 professors!! www.veredus.co.uk/job/job-747a/. Contact me for a chat if interested.
Reposted by Alastair Lamb
Our first Centre for Cancer Evolution PI retreat! A wonderful day at Goodenough House discussing science, strategy and forging new collaborations @qmbci.bsky.social
October 1, 2025 at 12:00 PM
Our first Centre for Cancer Evolution PI retreat! A wonderful day at Goodenough House discussing science, strategy and forging new collaborations @qmbci.bsky.social
•Are you a data scientist / bioinformatician?
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
May 8, 2025 at 8:38 AM
•Are you a data scientist / bioinformatician?
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
Really loved @10xgenomics.bsky.social session @theaacr.bsky.social #AACR25 #SpotlightPresentation by Jingxian Liu on Tumour Evolution & Clonal detection using Visium spatial tech.
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
April 30, 2025 at 5:06 PM
Really loved @10xgenomics.bsky.social session @theaacr.bsky.social #AACR25 #SpotlightPresentation by Jingxian Liu on Tumour Evolution & Clonal detection using Visium spatial tech.
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
Brilliant session focused entirely on spatial multiomics @theaacr.bsky.social #AUA25
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
April 29, 2025 at 8:25 PM
Brilliant session focused entirely on spatial multiomics @theaacr.bsky.social #AUA25
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
Really enjoyed this deep dive into intratumoural immune archetypes from Matt Krummel
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
April 29, 2025 at 1:57 PM
Really enjoyed this deep dive into intratumoural immune archetypes from Matt Krummel
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
Reposted by Alastair Lamb
Join us in welcoming Alastair Lamb (@lambalastair.bsky.social) to the BCI @qmulfmd.bsky.social. Dr Lamb will launch the next phase of his research into #prostatecancer, supported by a new £1.6m grant from @cancerresearchuk.org
📰 Read more: www.bci.qmul.ac.uk/general-news...
🧪 #medsky #oncosky
📰 Read more: www.bci.qmul.ac.uk/general-news...
🧪 #medsky #oncosky
Introducing: Dr Alastair Lamb - Barts Cancer Institute - Queen Mary University of London
We are delighted to welcome Alastair Lamb to the Barts Cancer Institute (BCI) at Queen Mary University of London. Dr Lamb joins our Centre for Cancer Evolution, where he will launch the next phase of ...
www.bci.qmul.ac.uk
April 3, 2025 at 11:50 AM
Join us in welcoming Alastair Lamb (@lambalastair.bsky.social) to the BCI @qmulfmd.bsky.social. Dr Lamb will launch the next phase of his research into #prostatecancer, supported by a new £1.6m grant from @cancerresearchuk.org
📰 Read more: www.bci.qmul.ac.uk/general-news...
🧪 #medsky #oncosky
📰 Read more: www.bci.qmul.ac.uk/general-news...
🧪 #medsky #oncosky
Reposted by Alastair Lamb
Welcome to the Faculty, @lambalastair.bsky.social
Join us in welcoming Alastair Lamb (@lambalastair.bsky.social) to the BCI @qmulfmd.bsky.social. Dr Lamb will launch the next phase of his research into #prostatecancer, supported by a new £1.6m grant from @cancerresearchuk.org
📰 Read more: www.bci.qmul.ac.uk/general-news...
🧪 #medsky #oncosky
📰 Read more: www.bci.qmul.ac.uk/general-news...
🧪 #medsky #oncosky
Introducing: Dr Alastair Lamb - Barts Cancer Institute - Queen Mary University of London
We are delighted to welcome Alastair Lamb to the Barts Cancer Institute (BCI) at Queen Mary University of London. Dr Lamb joins our Centre for Cancer Evolution, where he will launch the next phase of ...
www.bci.qmul.ac.uk
April 3, 2025 at 12:11 PM
Welcome to the Faculty, @lambalastair.bsky.social
Reposted by Alastair Lamb
Few teasers here from our breaking news GU Cast yesterday on TRANSLATE trial #eau25 @lambalastair.bsky.social and team
March 24, 2025 at 7:30 AM
Few teasers here from our breaking news GU Cast yesterday on TRANSLATE trial #eau25 @lambalastair.bsky.social and team
Reposted by Alastair Lamb
Congratulations to BJUI Global Prize winners Arthur Yim and Matthew Alberto for their #OpenAccess paper 'Near-infrared spectroscopy as a novel method of ex vivo bladder cancer tissue characterisation', presented today at #USANZ25
doi.org/10.1111/bju....
doi.org/10.1111/bju....
March 2, 2025 at 3:04 AM
Congratulations to BJUI Global Prize winners Arthur Yim and Matthew Alberto for their #OpenAccess paper 'Near-infrared spectroscopy as a novel method of ex vivo bladder cancer tissue characterisation', presented today at #USANZ25
doi.org/10.1111/bju....
doi.org/10.1111/bju....
Great talk from @thineskrishna.bsky.social on #RadioSpatialGenomics & machine learning approaches to #ProstateCancer risk stratification, fusing spatial tissue data w high quality #mpMRI
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
February 6, 2025 at 12:01 PM
Great talk from @thineskrishna.bsky.social on #RadioSpatialGenomics & machine learning approaches to #ProstateCancer risk stratification, fusing spatial tissue data w high quality #mpMRI
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
Good to be involved in the @cancerresearchuk.org #ClinicalReseachers meeting at @rcn.org.uk Cavendish Sq.
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
February 6, 2025 at 10:29 AM
Good to be involved in the @cancerresearchuk.org #ClinicalReseachers meeting at @rcn.org.uk Cavendish Sq.
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
Nice talk on #SpatialProteomics from @coscialab.bsky.social at #FoG2025 @fogenomics.bsky.social
Essential to unlock phenotype & prelude to biomarker discovery
Essential to unlock phenotype & prelude to biomarker discovery
January 30, 2025 at 2:33 PM
Nice talk on #SpatialProteomics from @coscialab.bsky.social at #FoG2025 @fogenomics.bsky.social
Essential to unlock phenotype & prelude to biomarker discovery
Essential to unlock phenotype & prelude to biomarker discovery
•Are you a data scientist/bioinformatician/computational biologist?
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
January 30, 2025 at 8:58 AM
•Are you a data scientist/bioinformatician/computational biologist?
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
Really enjoyed @mirjana-efremova.bsky.social talk on phenotypic plasticity in #ColorectalCancer
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
January 29, 2025 at 3:21 PM
Really enjoyed @mirjana-efremova.bsky.social talk on phenotypic plasticity in #ColorectalCancer
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
Cool to be at #FoG2025 @fogenomics.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
January 29, 2025 at 12:58 PM
Cool to be at #FoG2025 @fogenomics.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
Reposted by Alastair Lamb
2. Nice data. One again show outcomes from #prostatecancer. But avg. age 75 in HIFU cohort and 50% had Gleason 6. Overtreatment common - albeit with less morbid Rx. Confirm need for RCTs @londonprostate1.bsky.social @ip-london.bsky.social @euplatinum.bsky.social @ox.ac.uk @lambalastair.bsky.social
January 10, 2025 at 8:32 AM
2. Nice data. One again show outcomes from #prostatecancer. But avg. age 75 in HIFU cohort and 50% had Gleason 6. Overtreatment common - albeit with less morbid Rx. Confirm need for RCTs @londonprostate1.bsky.social @ip-london.bsky.social @euplatinum.bsky.social @ox.ac.uk @lambalastair.bsky.social
V cool to be starting first proper day @QMBCI.bsky.social Charterhouse Sq! Thanks to Francesca C & Nitzan Rosenfeld for taking me on as Group Leader in Centre for Cancer Evolution🧬. And to Guys Urology for making it work🙏
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
January 6, 2025 at 5:27 PM
V cool to be starting first proper day @QMBCI.bsky.social Charterhouse Sq! Thanks to Francesca C & Nitzan Rosenfeld for taking me on as Group Leader in Centre for Cancer Evolution🧬. And to Guys Urology for making it work🙏
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!