Alastair Lamb
@lambalastair.bsky.social
Prostate Cancer @CancerResearchUK.org Clinician Scientist. Urologist. Robotics | #SPACE_Study PI | @TranslateTrial CI | @BJUIJournal.bsky.social SE pros/web | Views own. RT=endsmt
Nice #LightningTalk from @maxbeesley.bsky.social as part of #PPCG 2025 meeting
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
November 13, 2025 at 12:37 PM
Nice #LightningTalk from @maxbeesley.bsky.social as part of #PPCG 2025 meeting
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
Using @10xgenomics.bsky.social #Visium & #inferCNV to spatially profile clonal heterogeneity & metastasis in #ProstateCancer
#SPACE_Study
@Pinkykotecha.bsky.social
@thineskrishna.bsky.social
@sandyfigiel.bsky.social
Real treat to hear Ros Eeles explain rationale for genetic risk in #ProstateCancer screening.
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
November 12, 2025 at 1:35 PM
Real treat to hear Ros Eeles explain rationale for genetic risk in #ProstateCancer screening.
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
A few key observations
•~50% of genetic risk still unknown (N.B. was 95% 10 yrs ago)
•difference between common (RR x2) and rare (RR 5-10x) variants
•Most RR refers to any PCa NOT lethal disease
#PPCG
Great work from @maxbeesley.bsky.social in his first #WhiteboardPresentation to assembled @qmbci.bsky.social #CEV!!
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
November 7, 2025 at 6:14 PM
Great work from @maxbeesley.bsky.social in his first #WhiteboardPresentation to assembled @qmbci.bsky.social #CEV!!
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
#ClonalEvolution
#SpatialBiology
#SPACE_Study #ProstateCancer
@mcclellandlab.bsky.social @ciccarellilab.bsky.social
Great to be at @kingscollegelondon.bsky.social #SpatialBiology Day in Robens Suite atop #GuysTower
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
October 20, 2025 at 1:09 PM
Great to be at @kingscollegelondon.bsky.social #SpatialBiology Day in Robens Suite atop #GuysTower
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
Exciting to see critical mass of spatial tech, bioinformatics, biobanking, metallomics expertise and more
@habkcl.bsky.social
@10xgenomics.bsky.social
Really enjoyed 1st Faculty Retreat for @qmbci.bsky.social Centre for Cancer Evolution #CEV PIs
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
October 2, 2025 at 3:09 PM
Really enjoyed 1st Faculty Retreat for @qmbci.bsky.social Centre for Cancer Evolution #CEV PIs
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
Great chance to share visions for our groups alongside needs/aspirations/collabs
@ciccarellilab.bsky.social @mcclellandlab.bsky.social
@mirjana-efremova.bsky.social
Alex W, Michelle L, Ben W, Stuart McD
•Are you a data scientist / bioinformatician?
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
May 8, 2025 at 8:38 AM
•Are you a data scientist / bioinformatician?
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
•Interested in #DeepLearning applied to #SpatialBiology?
•Do you want to transform #ProstateCancer clinical decision-making?
Based @QMBCI.bsky.social
Apply here!! 👇 (closing date 20th May)
qmul-jobs.tal.net/vx/candidate...
#SPACE_Study #Organscale
Really loved @10xgenomics.bsky.social session @theaacr.bsky.social #AACR25 #SpotlightPresentation by Jingxian Liu on Tumour Evolution & Clonal detection using Visium spatial tech.
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
April 30, 2025 at 5:06 PM
Really loved @10xgenomics.bsky.social session @theaacr.bsky.social #AACR25 #SpotlightPresentation by Jingxian Liu on Tumour Evolution & Clonal detection using Visium spatial tech.
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
Can't wait to set up some collaborative conversations with the Ding Lab @washumedicine.bsky.social!
@qmbci.bsky.social
Brilliant session focused entirely on spatial multiomics @theaacr.bsky.social #AUA25
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
April 29, 2025 at 8:25 PM
Brilliant session focused entirely on spatial multiomics @theaacr.bsky.social #AUA25
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
Well said @tanevski.bsky.social "Cancer is a spatial disease-spatialomics is the future of cancer science"!
Wonderful composite spatial data from Linghua Wang @mdanderson.bsky.social
www.nature.com/articles/s41...
Really enjoyed this deep dive into intratumoural immune archetypes from Matt Krummel
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
April 29, 2025 at 1:57 PM
Really enjoyed this deep dive into intratumoural immune archetypes from Matt Krummel
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
#AACR25 @TheAACR.bsky.social
Loved this video on T Cell vs Dendritic Cell interacting
#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity
Great talk from @thineskrishna.bsky.social on #RadioSpatialGenomics & machine learning approaches to #ProstateCancer risk stratification, fusing spatial tissue data w high quality #mpMRI
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
February 6, 2025 at 12:01 PM
Great talk from @thineskrishna.bsky.social on #RadioSpatialGenomics & machine learning approaches to #ProstateCancer risk stratification, fusing spatial tissue data w high quality #mpMRI
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
@cancerresearchuk.org #ClinicalResearchMeeting
#SPACE_Study
@ndsurgicalsci.bsky.social
@oxfordcancer.bsky.social
Good to be involved in the @cancerresearchuk.org #ClinicalReseachers meeting at @rcn.org.uk Cavendish Sq.
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
February 6, 2025 at 10:29 AM
Good to be involved in the @cancerresearchuk.org #ClinicalReseachers meeting at @rcn.org.uk Cavendish Sq.
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
Great opportunity to meet other #ClinicianScientists, network & discuss high quality science.
@thineskrishna.bsky.social @charlesswanton.bsky.social
@clareturnbull.bsky.social
Nice talk on #SpatialProteomics from @coscialab.bsky.social at #FoG2025 @fogenomics.bsky.social
Essential to unlock phenotype & prelude to biomarker discovery
Essential to unlock phenotype & prelude to biomarker discovery
January 30, 2025 at 2:33 PM
Nice talk on #SpatialProteomics from @coscialab.bsky.social at #FoG2025 @fogenomics.bsky.social
Essential to unlock phenotype & prelude to biomarker discovery
Essential to unlock phenotype & prelude to biomarker discovery
•Are you a data scientist/bioinformatician/computational biologist?
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
January 30, 2025 at 8:58 AM
•Are you a data scientist/bioinformatician/computational biologist?
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
•Are you interested in #SpatialGenomics?
•Do you want to apply your skills to big questions in #ProstateCancer?
Apply here!! 👇 (closing date 12th Feb)
qmul-jobs.tal.net/candidate/so...
#SPACE_Study #Organscale @qmbci.bsky.social
Really enjoyed @mirjana-efremova.bsky.social talk on phenotypic plasticity in #ColorectalCancer
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
January 29, 2025 at 3:21 PM
Really enjoyed @mirjana-efremova.bsky.social talk on phenotypic plasticity in #ColorectalCancer
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
Super clear explanation of role of key genes ( #LRIG1 etc) in cell switch
@qmbci.bsky.social
@ciccarellilab.bsky.social
@drtanyasoliman.bsky.social
@mcclellandlab.bsky.social
@sibucz.bsky.social
Cool to be at #FoG2025 @fogenomics.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
January 29, 2025 at 12:58 PM
Cool to be at #FoG2025 @fogenomics.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
A bit more #SpatialGenomics content this year which is great!
Surprise visit from #Darth & #Chewbacca!
@ciccarellilab.bsky.social @mirjana-efremova.bsky.social
@karlsmithbyrne.bsky.social
@qmbci.bsky.social
@omaiques.bsky.social
V cool to be starting first proper day @QMBCI.bsky.social Charterhouse Sq! Thanks to Francesca C & Nitzan Rosenfeld for taking me on as Group Leader in Centre for Cancer Evolution🧬. And to Guys Urology for making it work🙏
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
January 6, 2025 at 5:27 PM
V cool to be starting first proper day @QMBCI.bsky.social Charterhouse Sq! Thanks to Francesca C & Nitzan Rosenfeld for taking me on as Group Leader in Centre for Cancer Evolution🧬. And to Guys Urology for making it work🙏
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
Looking forward to rebuilding #SPACE_Study team here - recruiting soon!
Just out in @bmj.com, our "Uncertainties in Practice" article on #LATP vs #TRUS
We highlight evidence so far, discordance between recommendations (@UroWeb.bsky.social vs @NIHR.bsky.social vs #AUA) & need for nuance (!)
Not long now until #TranslateTrial...
bmj.com/content/387/bm…👈
We highlight evidence so far, discordance between recommendations (@UroWeb.bsky.social vs @NIHR.bsky.social vs #AUA) & need for nuance (!)
Not long now until #TranslateTrial...
bmj.com/content/387/bm…👈
December 2, 2024 at 3:34 PM
Just out in @bmj.com, our "Uncertainties in Practice" article on #LATP vs #TRUS
We highlight evidence so far, discordance between recommendations (@UroWeb.bsky.social vs @NIHR.bsky.social vs #AUA) & need for nuance (!)
Not long now until #TranslateTrial...
bmj.com/content/387/bm…👈
We highlight evidence so far, discordance between recommendations (@UroWeb.bsky.social vs @NIHR.bsky.social vs #AUA) & need for nuance (!)
Not long now until #TranslateTrial...
bmj.com/content/387/bm…👈
Really useful 2 days #UR-UK in Bristol. Meeting of 32 research-active UK urologists
ToR: networking to identify areas for game-changing research in Uro-oncology
Grateful for support from TUF, J&J, Astellas & Medac
Will be fascinating to see organic development of this group over next few years.
ToR: networking to identify areas for game-changing research in Uro-oncology
Grateful for support from TUF, J&J, Astellas & Medac
Will be fascinating to see organic development of this group over next few years.
November 22, 2024 at 3:05 PM
Really useful 2 days #UR-UK in Bristol. Meeting of 32 research-active UK urologists
ToR: networking to identify areas for game-changing research in Uro-oncology
Grateful for support from TUF, J&J, Astellas & Medac
Will be fascinating to see organic development of this group over next few years.
ToR: networking to identify areas for game-changing research in Uro-oncology
Grateful for support from TUF, J&J, Astellas & Medac
Will be fascinating to see organic development of this group over next few years.
Really looking forward to two days brainstorming on urological research at inaugural #UR-UK meeting in Bristol with @jonathananing.bsky.social, @mralexlaird.bsky.social, @tomjmitchell.bsky.social, @maxinegbtran.bsky.social et al.
@BAUSurology.bsky.social
Thanks @TUF.bsky.social for support!
@BAUSurology.bsky.social
Thanks @TUF.bsky.social for support!
November 21, 2024 at 10:08 AM
Really looking forward to two days brainstorming on urological research at inaugural #UR-UK meeting in Bristol with @jonathananing.bsky.social, @mralexlaird.bsky.social, @tomjmitchell.bsky.social, @maxinegbtran.bsky.social et al.
@BAUSurology.bsky.social
Thanks @TUF.bsky.social for support!
@BAUSurology.bsky.social
Thanks @TUF.bsky.social for support!
Great quote from the lovely Selena Kim, former PhD student of Prof Val Macaulay
"Val taught me how to be a logical but creative scientist...and the importance of humility and compassion in how we work"
"Val taught me how to be a logical but creative scientist...and the importance of humility and compassion in how we work"
November 20, 2024 at 2:33 PM
Great quote from the lovely Selena Kim, former PhD student of Prof Val Macaulay
"Val taught me how to be a logical but creative scientist...and the importance of humility and compassion in how we work"
"Val taught me how to be a logical but creative scientist...and the importance of humility and compassion in how we work"
Moving to attend memorial symposium for our recently departed friend & colleague Prof Val Macaulay
Amazing career in #IGF-1 signalling & #ProstateCancer
Perhaps even more significantly in supervising 30+ PhDs & widely known for her quiet empathy & compassion, alongside scientific sharpness & drive
Amazing career in #IGF-1 signalling & #ProstateCancer
Perhaps even more significantly in supervising 30+ PhDs & widely known for her quiet empathy & compassion, alongside scientific sharpness & drive
November 20, 2024 at 2:25 PM
Moving to attend memorial symposium for our recently departed friend & colleague Prof Val Macaulay
Amazing career in #IGF-1 signalling & #ProstateCancer
Perhaps even more significantly in supervising 30+ PhDs & widely known for her quiet empathy & compassion, alongside scientific sharpness & drive
Amazing career in #IGF-1 signalling & #ProstateCancer
Perhaps even more significantly in supervising 30+ PhDs & widely known for her quiet empathy & compassion, alongside scientific sharpness & drive
Belated post to thank @BAUSurology.bsky.social Oncology Section for excellent meeting in Nottingham #BAUSOncology2024. Cutting edge talks & stimulating conversation!
Think we're on the cusp of something new & exciting with upcoming #UR-UK (Uro-oncology Research UK) inaugural meeting...
Think we're on the cusp of something new & exciting with upcoming #UR-UK (Uro-oncology Research UK) inaugural meeting...
November 19, 2024 at 12:35 PM
Belated post to thank @BAUSurology.bsky.social Oncology Section for excellent meeting in Nottingham #BAUSOncology2024. Cutting edge talks & stimulating conversation!
Think we're on the cusp of something new & exciting with upcoming #UR-UK (Uro-oncology Research UK) inaugural meeting...
Think we're on the cusp of something new & exciting with upcoming #UR-UK (Uro-oncology Research UK) inaugural meeting...
Made the most of being (technically) unemployed this morning ❄️🌨☃️!! Now to crack on with some journal reviews that have been stacking up for @bjuijournal.bsky.social...
#SnowInOxford
#BetweenJobs
#SnowInOxford
#BetweenJobs
November 19, 2024 at 12:14 PM
Made the most of being (technically) unemployed this morning ❄️🌨☃️!! Now to crack on with some journal reviews that have been stacking up for @bjuijournal.bsky.social...
#SnowInOxford
#BetweenJobs
#SnowInOxford
#BetweenJobs