Kostas Papadakos
@kpapadakos.bsky.social
Cancer biology , Lund University
Pinned
Kostas Papadakos
@kpapadakos.bsky.social
· Nov 16
Intracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy - Cell Death & Disease
Cell Death & Disease - Intracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy
www.nature.com
Our newest publication examines whether an extracellular matrix protein has an intracellular function. Yes, it provides resistance to all known therapies for breast cancer.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Kostas Papadakos
There's a month left for you to submit an abstract or apply for a Travel Grant to attend the next edition of Defence is the Best Attack, taking place in Barcelona in May! ☀️
Join us for an overview of the most recent advances in the field of immunotherapy:
eacr.org/conference/d...
Join us for an overview of the most recent advances in the field of immunotherapy:
eacr.org/conference/d...
February 17, 2025 at 10:22 AM
There's a month left for you to submit an abstract or apply for a Travel Grant to attend the next edition of Defence is the Best Attack, taking place in Barcelona in May! ☀️
Join us for an overview of the most recent advances in the field of immunotherapy:
eacr.org/conference/d...
Join us for an overview of the most recent advances in the field of immunotherapy:
eacr.org/conference/d...
Reposted by Kostas Papadakos
Submit your abstract and apply for a Travel Grant to attend Persister Cells 2025!
Taking place in Lyon, this conference will delve into molecular mechanisms, therapeutic targets and emerging clinical implications of cancer persister cells.
eacr.org/conference/p...
Taking place in Lyon, this conference will delve into molecular mechanisms, therapeutic targets and emerging clinical implications of cancer persister cells.
eacr.org/conference/p...
December 5, 2024 at 1:52 PM
Submit your abstract and apply for a Travel Grant to attend Persister Cells 2025!
Taking place in Lyon, this conference will delve into molecular mechanisms, therapeutic targets and emerging clinical implications of cancer persister cells.
eacr.org/conference/p...
Taking place in Lyon, this conference will delve into molecular mechanisms, therapeutic targets and emerging clinical implications of cancer persister cells.
eacr.org/conference/p...
Reposted by Kostas Papadakos
Just recently I wrote an opinion piece with Shingo Kajimura, based around the idea that adipocytes, besides having energy storage/endocrine function, also act as immune hubs #Immunosky 🧪
1/🧵
febs.onlinelibrary.wiley.com/doi/10.1111/...
1/🧵
febs.onlinelibrary.wiley.com/doi/10.1111/...
FEBS Press
Traditionally, adipocytes have been viewed as energy storage units, which upregulate inflammatory factors in response to obesity. However, emerging evidence demonstrates that adipocytes are highly re...
febs.onlinelibrary.wiley.com
December 7, 2024 at 9:31 AM
Just recently I wrote an opinion piece with Shingo Kajimura, based around the idea that adipocytes, besides having energy storage/endocrine function, also act as immune hubs #Immunosky 🧪
1/🧵
febs.onlinelibrary.wiley.com/doi/10.1111/...
1/🧵
febs.onlinelibrary.wiley.com/doi/10.1111/...
I love this kind of science go.nature.com/4i3gqUI
Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts - Nature Microbiology
Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome.
go.nature.com
November 25, 2024 at 2:10 PM
I love this kind of science go.nature.com/4i3gqUI
Reposted by Kostas Papadakos
Meet our PhD student Rebecca! This year, she beat cancer AND published her first 1st-author paper on how hypoxia induces complement signaling in GBM, alters macrophage polarization, and how the C3-C3AR1 axis can be therapeutically targeted in GBM models. Check it out! insight.jci.org/articles/vie...
November 19, 2024 at 12:59 PM
Meet our PhD student Rebecca! This year, she beat cancer AND published her first 1st-author paper on how hypoxia induces complement signaling in GBM, alters macrophage polarization, and how the C3-C3AR1 axis can be therapeutically targeted in GBM models. Check it out! insight.jci.org/articles/vie...
Reposted by Kostas Papadakos
Nooooooo 😱 www.nature.com/articles/s41...
Adipose tissue retains an epigenetic memory of obesity after weight loss - Nature
Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to th...
www.nature.com
November 19, 2024 at 7:27 AM
Nooooooo 😱 www.nature.com/articles/s41...
Reposted by Kostas Papadakos
Hi #cancer, #ECMatrix, #biomaterials and #mechanobiology folks:
Below a Nat Cell Biol paper from the Chen and Weaver groups, of interest to many of us 🧪👇:
www.nature.com/articles/s41...
Below a Nat Cell Biol paper from the Chen and Weaver groups, of interest to many of us 🧪👇:
www.nature.com/articles/s41...
Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option - Nature Cell Biology
Uroz et al. report that the distinct mechanical properties of brain vasculature versus parenchyma drive cancer cell migration through a talin-dependent mechanism, enabling vessel co-option and metasta...
www.nature.com
November 18, 2024 at 10:14 AM
Hi #cancer, #ECMatrix, #biomaterials and #mechanobiology folks:
Below a Nat Cell Biol paper from the Chen and Weaver groups, of interest to many of us 🧪👇:
www.nature.com/articles/s41...
Below a Nat Cell Biol paper from the Chen and Weaver groups, of interest to many of us 🧪👇:
www.nature.com/articles/s41...
Our newest publication examines whether an extracellular matrix protein has an intracellular function. Yes, it provides resistance to all known therapies for breast cancer.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Intracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy - Cell Death & Disease
Cell Death & Disease - Intracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy
www.nature.com
November 16, 2024 at 12:31 PM
Our newest publication examines whether an extracellular matrix protein has an intracellular function. Yes, it provides resistance to all known therapies for breast cancer.
www.nature.com/articles/s41...
www.nature.com/articles/s41...