Korak Ray
@korakray.bsky.social
Interested in biophysical chemistry, single molecules, and nucleic acids. Into puns and speculative fiction.
Postdoc @Rueda Lab, MRC LMS.
He/him
Postdoc @Rueda Lab, MRC LMS.
He/him
A bit of good news!
Part of my PhD work in collaboration with @ssjang.bsky.social and David Lynall is out in @narjournal.bsky.social! We uncover a surprising mechanism by which an ultrastable RNA stem-loop tunes its flexibility, enabling it to both fold rapidly and resist unfolding.
Part of my PhD work in collaboration with @ssjang.bsky.social and David Lynall is out in @narjournal.bsky.social! We uncover a surprising mechanism by which an ultrastable RNA stem-loop tunes its flexibility, enabling it to both fold rapidly and resist unfolding.
New from our lab in @narjournal.bsky.social:
We dissect the folding dynamics of a fundamental element of RNA secondary structure—a stem-loop—at single-molecule and microsecond resolution.
doi.org/10.1093/nar/... 1/5
We dissect the folding dynamics of a fundamental element of RNA secondary structure—a stem-loop—at single-molecule and microsecond resolution.
doi.org/10.1093/nar/... 1/5
July 31, 2025 at 10:52 AM
A bit of good news!
Part of my PhD work in collaboration with @ssjang.bsky.social and David Lynall is out in @narjournal.bsky.social! We uncover a surprising mechanism by which an ultrastable RNA stem-loop tunes its flexibility, enabling it to both fold rapidly and resist unfolding.
Part of my PhD work in collaboration with @ssjang.bsky.social and David Lynall is out in @narjournal.bsky.social! We uncover a surprising mechanism by which an ultrastable RNA stem-loop tunes its flexibility, enabling it to both fold rapidly and resist unfolding.
Reposted by Korak Ray
Exciting new research from the Cellular Stress and Single Molecule Imaging groups has created a new technique for transfecting cells that could pave the way for new gene therapies!
We'll be recapping some of the highlights from the article in this thread.
🧵1/6
We'll be recapping some of the highlights from the article in this thread.
🧵1/6
Precise intracellular uptake and endosomal release of diverse functional mRNA payloads via glutathione-responsive nanogels
We present a novel, highly customizable glutathione-responsive nanogel (NG) platform for efficient mRNA delivery with precise mRNA payload release con…
www.sciencedirect.com
January 10, 2025 at 11:54 AM
Exciting new research from the Cellular Stress and Single Molecule Imaging groups has created a new technique for transfecting cells that could pave the way for new gene therapies!
We'll be recapping some of the highlights from the article in this thread.
🧵1/6
We'll be recapping some of the highlights from the article in this thread.
🧵1/6
tMAVEN, our open-source comprehensive platform for single-molecule data analysis, is finally here! Check out our article describing the platform and how we use it to investigate the use of kinetic models to extract mechanistic info from data, out in Biophys J. www.sciencedirect.com/science/arti...
Increasing the accuracy of single-molecule data analysis using tMAVEN
Time-dependent single-molecule experiments contain rich kinetic information about the functional dynamics of biomolecules. A key step in extracting th…
www.sciencedirect.com
February 10, 2024 at 12:10 AM
tMAVEN, our open-source comprehensive platform for single-molecule data analysis, is finally here! Check out our article describing the platform and how we use it to investigate the use of kinetic models to extract mechanistic info from data, out in Biophys J. www.sciencedirect.com/science/arti...
Reposted by Korak Ray
Spooky season reminder that, at its core, The Monster Mash is a cautionary tale about working in the lab late one night and, ultimately, the dangers of poor work/life balance under late capitalism.
October 23, 2023 at 5:02 PM
Spooky season reminder that, at its core, The Monster Mash is a cautionary tale about working in the lab late one night and, ultimately, the dangers of poor work/life balance under late capitalism.
🚨 Preprint news!! 🚨 The collaboration with @ckinzthompson on a novel definition of resolution and how it can be used to calculate the local atomic resolution and map-to-model correspondence in cryoEM structures is finally on bioRxiv!!!! www.biorxiv.org/content/10.1... 🧵(1/6)
Scale-dependent hierarchical resolution: applications to atomic resolution and model validation in c...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
October 20, 2023 at 7:35 PM
🚨 Preprint news!! 🚨 The collaboration with @ckinzthompson on a novel definition of resolution and how it can be used to calculate the local atomic resolution and map-to-model correspondence in cryoEM structures is finally on bioRxiv!!!! www.biorxiv.org/content/10.1... 🧵(1/6)
Reposted by Korak Ray
BREAKING NEWS: Three scientists have won the 2023 #NobelPrize in Chemistry for their research on the discovery and synthesis of quantum dots. Moungi G. Bawendi, Louis E. Brus and Alexei I. Ekimov share prize for research that added color to nanotechnology: cen.acs.org/people/nobel...
November 18, 2024 at 10:30 PM
BREAKING NEWS: Three scientists have won the 2023 #NobelPrize in Chemistry for their research on the discovery and synthesis of quantum dots. Moungi G. Bawendi, Louis E. Brus and Alexei I. Ekimov share prize for research that added color to nanotechnology: cen.acs.org/people/nobel...