Kevin Monahan
@kevinmonahan.bsky.social
Gastroenterologist from @StMarksGenomics.bskyb.social with an interest in hereditary bowel cancer and occasional rants about other random things
https://profiles.imperial.ac.uk/k.monahan
https://profiles.imperial.ac.uk/k.monahan
We had the 3rd meeting of the UK EOCRC Research Consortium in beautiful Edinburgh yesterday supported by British Society of Gastroenterology (BSG) and @bowelcanceruk.bsky.social attended by over 50 UK academics - celebrating our first project funding success only 1 year after foundation
November 12, 2025 at 6:37 AM
We had the 3rd meeting of the UK EOCRC Research Consortium in beautiful Edinburgh yesterday supported by British Society of Gastroenterology (BSG) and @bowelcanceruk.bsky.social attended by over 50 UK academics - celebrating our first project funding success only 1 year after foundation
Reposted by Kevin Monahan
James D Watson, co-discoverer of the structure of DNA, dies aged 97
James D Watson, co-discoverer of the structure of DNA, dies aged 97
Remembered for breakthrough with Francis Crick, Watson was later ostracised by the scientific establishment over comments on race
www.irishtimes.com
November 7, 2025 at 9:09 PM
James D Watson, co-discoverer of the structure of DNA, dies aged 97
Reposted by Kevin Monahan
And they’re off! 🏁 👟
Elaine Burns🚶♀️Vs Danilo Miskovic 🏃
Our colon cancer workshop is on day 2 of ‘Frontiers’ - run or walk with our experts 🌟
(Must watch video below 👇🏻😜)
Sign up to be in with a chance to participate - bit.ly/4ktsvDc
@lnwh.bsky.social
@kevinmonahan.bsky.social
Elaine Burns🚶♀️Vs Danilo Miskovic 🏃
Our colon cancer workshop is on day 2 of ‘Frontiers’ - run or walk with our experts 🌟
(Must watch video below 👇🏻😜)
Sign up to be in with a chance to participate - bit.ly/4ktsvDc
@lnwh.bsky.social
@kevinmonahan.bsky.social
October 17, 2025 at 8:14 AM
And they’re off! 🏁 👟
Elaine Burns🚶♀️Vs Danilo Miskovic 🏃
Our colon cancer workshop is on day 2 of ‘Frontiers’ - run or walk with our experts 🌟
(Must watch video below 👇🏻😜)
Sign up to be in with a chance to participate - bit.ly/4ktsvDc
@lnwh.bsky.social
@kevinmonahan.bsky.social
Elaine Burns🚶♀️Vs Danilo Miskovic 🏃
Our colon cancer workshop is on day 2 of ‘Frontiers’ - run or walk with our experts 🌟
(Must watch video below 👇🏻😜)
Sign up to be in with a chance to participate - bit.ly/4ktsvDc
@lnwh.bsky.social
@kevinmonahan.bsky.social
'Everybody's unique in their own way' - Tadej Pogačar
Love this guy - The true #GOAT
www.cyclingnews.com/news/everybo...
Love this guy - The true #GOAT
www.cyclingnews.com/news/everybo...
'Everybody's unique in their own way' - Tadej Pogačar plays down greatness after record-breaking fifth consecutive Il Lombardia victory
Pogačar dedicates his victory to teammate Rafał Majka
www.cyclingnews.com
October 11, 2025 at 7:25 PM
'Everybody's unique in their own way' - Tadej Pogačar
Love this guy - The true #GOAT
www.cyclingnews.com/news/everybo...
Love this guy - The true #GOAT
www.cyclingnews.com/news/everybo...
Reposted by Kevin Monahan
I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...
DNA mutagenesis driven by transcription factor competition with mismatch repair
Competition between transcription factors and mismatch repair machinery drives localized
hypermutation at regulatory elements, with implications for cancer and genome evolution.
www.cell.com
October 2, 2025 at 11:37 PM
I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...
Reposted by Kevin Monahan
Can we prevent IBD?
We are delighted to have Prof. Johan Burisch as one of our visiting professors for this years Frontiers congress 🙌🏻
Hear more about Prof. Burisch in the video below ⬇️
Register now - bit.ly/4ktsvDc
@lnwh.bsky.social
@kevinmonahan.bsky.social
We are delighted to have Prof. Johan Burisch as one of our visiting professors for this years Frontiers congress 🙌🏻
Hear more about Prof. Burisch in the video below ⬇️
Register now - bit.ly/4ktsvDc
@lnwh.bsky.social
@kevinmonahan.bsky.social
October 3, 2025 at 8:28 AM
Can we prevent IBD?
We are delighted to have Prof. Johan Burisch as one of our visiting professors for this years Frontiers congress 🙌🏻
Hear more about Prof. Burisch in the video below ⬇️
Register now - bit.ly/4ktsvDc
@lnwh.bsky.social
@kevinmonahan.bsky.social
We are delighted to have Prof. Johan Burisch as one of our visiting professors for this years Frontiers congress 🙌🏻
Hear more about Prof. Burisch in the video below ⬇️
Register now - bit.ly/4ktsvDc
@lnwh.bsky.social
@kevinmonahan.bsky.social
Reposted by Kevin Monahan
Final Call for Abstracts – Deadline Today!⏳
Don't miss your chance to be part of the #InSiGHT2026 Biennial Meeting in #Singapore! 🌏
🗓️ Submission Deadline: 30 September 2025
⏰ Time: Midnight (Singapore Time) / 6pm CET
Submit your abstract now! insight2026.org/abstract-sub...
#Genetics #GIcancer
Don't miss your chance to be part of the #InSiGHT2026 Biennial Meeting in #Singapore! 🌏
🗓️ Submission Deadline: 30 September 2025
⏰ Time: Midnight (Singapore Time) / 6pm CET
Submit your abstract now! insight2026.org/abstract-sub...
#Genetics #GIcancer
September 30, 2025 at 10:05 AM
Final Call for Abstracts – Deadline Today!⏳
Don't miss your chance to be part of the #InSiGHT2026 Biennial Meeting in #Singapore! 🌏
🗓️ Submission Deadline: 30 September 2025
⏰ Time: Midnight (Singapore Time) / 6pm CET
Submit your abstract now! insight2026.org/abstract-sub...
#Genetics #GIcancer
Don't miss your chance to be part of the #InSiGHT2026 Biennial Meeting in #Singapore! 🌏
🗓️ Submission Deadline: 30 September 2025
⏰ Time: Midnight (Singapore Time) / 6pm CET
Submit your abstract now! insight2026.org/abstract-sub...
#Genetics #GIcancer
Reposted by Kevin Monahan
🚨 Final Call: Abstract submissions for #InSiGHT2026 close TOMORROW – Sept 30!
Join the global conversation on hereditary GI tumours.
Submit now 👉 insight2026.org
Let your research drive progress.
#MedicalResearch #Genetics #GIcancer #AbstractSubmission
Join the global conversation on hereditary GI tumours.
Submit now 👉 insight2026.org
Let your research drive progress.
#MedicalResearch #Genetics #GIcancer #AbstractSubmission
September 29, 2025 at 2:46 PM
🚨 Final Call: Abstract submissions for #InSiGHT2026 close TOMORROW – Sept 30!
Join the global conversation on hereditary GI tumours.
Submit now 👉 insight2026.org
Let your research drive progress.
#MedicalResearch #Genetics #GIcancer #AbstractSubmission
Join the global conversation on hereditary GI tumours.
Submit now 👉 insight2026.org
Let your research drive progress.
#MedicalResearch #Genetics #GIcancer #AbstractSubmission
Our results support universal and paired somatic and germline multi-gene panels for all EOCRC patients, regardless of MMR status or family history
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
September 27, 2025 at 2:40 PM
Our results support universal and paired somatic and germline multi-gene panels for all EOCRC patients, regardless of MMR status or family history
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Genetic testing appears to have limited utility in SPS patients and may primarily identify those with an incidental diagnosis of Lynch syndrome
pubmed.ncbi.nlm.nih.gov/41002021/
pubmed.ncbi.nlm.nih.gov/41002021/
Low Yield of Genetic Testing in Serrated Polyposis Syndrome - PubMed
Genetic testing demonstrated a low diagnostic yield in this SPS cohort, suggesting undefined genetic risk or involvement of other pathophysiological factors. Therefore, genetic testing appears to have...
pubmed.ncbi.nlm.nih.gov
September 27, 2025 at 12:10 PM
Genetic testing appears to have limited utility in SPS patients and may primarily identify those with an incidental diagnosis of Lynch syndrome
pubmed.ncbi.nlm.nih.gov/41002021/
pubmed.ncbi.nlm.nih.gov/41002021/
Reposted by Kevin Monahan
Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7)
rdcu.be/eFrrc
rdcu.be/eFrrc
Fluctuating DNA methylation tracks cancer evolution at clinical scale
Nature - Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.
rdcu.be
September 10, 2025 at 4:17 PM
Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7)
rdcu.be/eFrrc
rdcu.be/eFrrc
Reposted by Kevin Monahan
Lineage tracking using methylation states from longitudinal bulk sampling. Sounds 🆒 and given recent work by @trevorgraham.bsky.social and colleagues, looks real.
Wondering about other applications like 🦠🧫
👉🏻News and views: www.nature.com/articles/d41...
👉🏻Paper
www.nature.com/articles/s41...
Wondering about other applications like 🦠🧫
👉🏻News and views: www.nature.com/articles/d41...
👉🏻Paper
www.nature.com/articles/s41...
Epigenetic clues from cancer’s past foretell its future
An innovative method to trace tumour evolution using patterns of fluctuating DNA modifications could be implemented in the clinic to predict cancer progression.
www.nature.com
September 21, 2025 at 9:58 PM
Lineage tracking using methylation states from longitudinal bulk sampling. Sounds 🆒 and given recent work by @trevorgraham.bsky.social and colleagues, looks real.
Wondering about other applications like 🦠🧫
👉🏻News and views: www.nature.com/articles/d41...
👉🏻Paper
www.nature.com/articles/s41...
Wondering about other applications like 🦠🧫
👉🏻News and views: www.nature.com/articles/d41...
👉🏻Paper
www.nature.com/articles/s41...
Reposted by Kevin Monahan
🚨 It’s here!
The Scientific Program for InSiGHT 2026 (4–7 March, Singapore 🇸🇬) is now live!
🔗 Check out the full program: insight2026.org/scientific-programme
🧬 Abstracts due 30 Sept – submit yours: insight2026.org/abstract-submission-guidelines
#InSiGHT2026 #HereditaryCancer #GICancerResearch
The Scientific Program for InSiGHT 2026 (4–7 March, Singapore 🇸🇬) is now live!
🔗 Check out the full program: insight2026.org/scientific-programme
🧬 Abstracts due 30 Sept – submit yours: insight2026.org/abstract-submission-guidelines
#InSiGHT2026 #HereditaryCancer #GICancerResearch
September 19, 2025 at 1:18 PM
🚨 It’s here!
The Scientific Program for InSiGHT 2026 (4–7 March, Singapore 🇸🇬) is now live!
🔗 Check out the full program: insight2026.org/scientific-programme
🧬 Abstracts due 30 Sept – submit yours: insight2026.org/abstract-submission-guidelines
#InSiGHT2026 #HereditaryCancer #GICancerResearch
The Scientific Program for InSiGHT 2026 (4–7 March, Singapore 🇸🇬) is now live!
🔗 Check out the full program: insight2026.org/scientific-programme
🧬 Abstracts due 30 Sept – submit yours: insight2026.org/abstract-submission-guidelines
#InSiGHT2026 #HereditaryCancer #GICancerResearch
Reposted by Kevin Monahan
🚀 Exciting news! We’re launching Young-Insight for InSiGHT members under 40.
Join our first meeting to share ideas & shape the future of our community. Email admin@insight-group.org with subject “Young Insight” to get involved! 🌍✨ #InSiGHT
Join our first meeting to share ideas & shape the future of our community. Email admin@insight-group.org with subject “Young Insight” to get involved! 🌍✨ #InSiGHT
September 11, 2025 at 8:36 AM
🚀 Exciting news! We’re launching Young-Insight for InSiGHT members under 40.
Join our first meeting to share ideas & shape the future of our community. Email admin@insight-group.org with subject “Young Insight” to get involved! 🌍✨ #InSiGHT
Join our first meeting to share ideas & shape the future of our community. Email admin@insight-group.org with subject “Young Insight” to get involved! 🌍✨ #InSiGHT
The registries’ combined experiences underscore the critical need for integrated, culturally sensitive strategies combining genetic testing, enhanced surveillance, and family-based management to improve outcomes #Polyposis #LynchSyndrome
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Comparative insight: hereditary colorectal cancer registries in Iran, Singapore, and South Africa - Familial Cancer
This study compares three hereditary colorectal cancer (CRC) registries—the Iranian Hereditary Colorectal Cancer Registry (IHCCR), the Singapore Polyposis Registry (SPR), and the University of Cape To...
link.springer.com
September 6, 2025 at 1:51 PM
The registries’ combined experiences underscore the critical need for integrated, culturally sensitive strategies combining genetic testing, enhanced surveillance, and family-based management to improve outcomes #Polyposis #LynchSyndrome
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Kevin Monahan
📢 Join us in Singapore for the InSiGHT Biennial Meeting,
4–7 March 2026!
🔹 Abstract Deadline: 20 Sept 2025
🔹 Early Bird: 10 Jan 2026
Link ➡️ insight2026.org
Let’s advance hereditary GI cancer research together!
#InSiGHT2026 #MedicalResearch #GItumours
4–7 March 2026!
🔹 Abstract Deadline: 20 Sept 2025
🔹 Early Bird: 10 Jan 2026
Link ➡️ insight2026.org
Let’s advance hereditary GI cancer research together!
#InSiGHT2026 #MedicalResearch #GItumours
August 8, 2025 at 1:43 PM
📢 Join us in Singapore for the InSiGHT Biennial Meeting,
4–7 March 2026!
🔹 Abstract Deadline: 20 Sept 2025
🔹 Early Bird: 10 Jan 2026
Link ➡️ insight2026.org
Let’s advance hereditary GI cancer research together!
#InSiGHT2026 #MedicalResearch #GItumours
4–7 March 2026!
🔹 Abstract Deadline: 20 Sept 2025
🔹 Early Bird: 10 Jan 2026
Link ➡️ insight2026.org
Let’s advance hereditary GI cancer research together!
#InSiGHT2026 #MedicalResearch #GItumours
Come and work with us!
We are seeking a Regional #LynchSyndrome Nursing Lead band 8 for 12 months to provide teaching and training across North London #Genomics apps.trac.jobs/job-advert/7...
We are seeking a Regional #LynchSyndrome Nursing Lead band 8 for 12 months to provide teaching and training across North London #Genomics apps.trac.jobs/job-advert/7...
Regional Lynch Syndrome Nursing Lead | Job advert | Trac
apps.trac.jobs
August 11, 2025 at 2:10 PM
Come and work with us!
We are seeking a Regional #LynchSyndrome Nursing Lead band 8 for 12 months to provide teaching and training across North London #Genomics apps.trac.jobs/job-advert/7...
We are seeking a Regional #LynchSyndrome Nursing Lead band 8 for 12 months to provide teaching and training across North London #Genomics apps.trac.jobs/job-advert/7...
Reposted by Kevin Monahan
Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!
July 21, 2025 at 4:54 PM
Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!
Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!
July 21, 2025 at 4:54 PM
Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!
Reposted by Kevin Monahan
👋 Welcome to InSiGHT on BlueSky!
We are a global community of researchers, clinicians, and scientists dedicated to advancing the understanding, diagnosis, and management of hereditary GI cancers. Follow us for updates on scientific advances, clinical guidelines, and upcoming events. #InSiGHT
We are a global community of researchers, clinicians, and scientists dedicated to advancing the understanding, diagnosis, and management of hereditary GI cancers. Follow us for updates on scientific advances, clinical guidelines, and upcoming events. #InSiGHT
July 21, 2025 at 1:09 PM
👋 Welcome to InSiGHT on BlueSky!
We are a global community of researchers, clinicians, and scientists dedicated to advancing the understanding, diagnosis, and management of hereditary GI cancers. Follow us for updates on scientific advances, clinical guidelines, and upcoming events. #InSiGHT
We are a global community of researchers, clinicians, and scientists dedicated to advancing the understanding, diagnosis, and management of hereditary GI cancers. Follow us for updates on scientific advances, clinical guidelines, and upcoming events. #InSiGHT
Abstract submission is now open for #Insight2026 ! Deadline 7th September #LynchSyndrome #Polyposis #EOCRC @soniakupfer.bsky.social @swatipatelmd.bsky.social @cgaigc.com @stmarksgenomics.bsky.social @plsdatabase.bsky.social
insight2026.org
insight2026.org
InSIGHT 2026
REGISTRATION NOW OPEN Register NowCall for Abstracts Now Open! Submit Your AbstractWelcome MessageWelcome to Singapore, Selamat Datang, 欢迎, வருக வருக. On behalf of InSiGHT, we are delighted to invite....
insight2026.org
July 13, 2025 at 12:41 PM
Abstract submission is now open for #Insight2026 ! Deadline 7th September #LynchSyndrome #Polyposis #EOCRC @soniakupfer.bsky.social @swatipatelmd.bsky.social @cgaigc.com @stmarksgenomics.bsky.social @plsdatabase.bsky.social
insight2026.org
insight2026.org
Mainstreaming clinicians in colorectal and Gynae teams… think about this study!
July 7, 2025 at 6:01 PM
Mainstreaming clinicians in colorectal and Gynae teams… think about this study!
Reposted by Kevin Monahan
Join us 19-21 November for a bigger and better St Mark's Frontiers in Colorectal Disease Meeting, in a beautiful venue in King's Cross London!
Extremely good value, with hybrid options @stmarkshospital.bsky.social
sayso.health/events/front...
Extremely good value, with hybrid options @stmarkshospital.bsky.social
sayso.health/events/front...
St Mark's Frontiers 2025
Register now for our Annual Frontiers in Colorectal and Intestinal Disease Congress, from the 19th–21st November 2025.
sayso.health
July 1, 2025 at 2:26 PM
Join us 19-21 November for a bigger and better St Mark's Frontiers in Colorectal Disease Meeting, in a beautiful venue in King's Cross London!
Extremely good value, with hybrid options @stmarkshospital.bsky.social
sayso.health/events/front...
Extremely good value, with hybrid options @stmarkshospital.bsky.social
sayso.health/events/front...