Kevin Blyth
@kevingblyth.bsky.social
Professor of Respiratory Medicine @ University of Glasgow | Respiratory Consultant QEUH | Mesothelioma | Pleural | Lung | Cancer Evolution | Trustee Mesothelioma UK
https://www.predictmeso.com
https://pubmed.ncbi.nlm.nih.gov/?term=blyth+kg&sort=date
https://www.predictmeso.com
https://pubmed.ncbi.nlm.nih.gov/?term=blyth+kg&sort=date
Pinned
Kevin Blyth
@kevingblyth.bsky.social
· Dec 23
Lunchtime Live - 23/12/2024 - BBC Sounds
News updates from Scotland and beyond, plus all your lunchtime sport, travel and weather.
www.bbc.co.uk
A few mins of #Mesothelioma chat starts @1251 on BBC Scotland Lunchtime Live👇
Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?
@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org
www.bbc.co.uk/sounds/play/...
Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?
@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org
www.bbc.co.uk/sounds/play/...
Full text link below to a review article just published in Current Pulmonary Reports on Non-Specific Pleuritis. A key topic for those interested in #mesothelioma evolution.
Well done to first author Mark Neilly and thanks to our co-author and pathology colleague, Craig Dick 👏
rdcu.be/d9Fgg
Well done to first author Mark Neilly and thanks to our co-author and pathology colleague, Craig Dick 👏
rdcu.be/d9Fgg
Non-Specific Pleuritis: An Update
rdcu.be
February 13, 2025 at 8:34 PM
Full text link below to a review article just published in Current Pulmonary Reports on Non-Specific Pleuritis. A key topic for those interested in #mesothelioma evolution.
Well done to first author Mark Neilly and thanks to our co-author and pathology colleague, Craig Dick 👏
rdcu.be/d9Fgg
Well done to first author Mark Neilly and thanks to our co-author and pathology colleague, Craig Dick 👏
rdcu.be/d9Fgg
Great to be in beautiful Edinburgh for the National #Mesothelioma Education Day 2025 🏴
Dr Neil McGlinchey kicking off the meeting in fantastic setting at Royal College of Physicians
Dr Neil McGlinchey kicking off the meeting in fantastic setting at Royal College of Physicians
February 6, 2025 at 10:08 AM
Great to be in beautiful Edinburgh for the National #Mesothelioma Education Day 2025 🏴
Dr Neil McGlinchey kicking off the meeting in fantastic setting at Royal College of Physicians
Dr Neil McGlinchey kicking off the meeting in fantastic setting at Royal College of Physicians
Looking forward to this tomorrow ⬇️
National #Mesothelioma Network Education Day
✅ New Management Guideline
🩻 New Staging (TNM 9)
📈 Review of Audit Performance (QPI)
Plus Trials, Interventional Pain, Pleural Nursing & Horizon scanning
…then, dinner with team 🎉🍷
National #Mesothelioma Network Education Day
✅ New Management Guideline
🩻 New Staging (TNM 9)
📈 Review of Audit Performance (QPI)
Plus Trials, Interventional Pain, Pleural Nursing & Horizon scanning
…then, dinner with team 🎉🍷
February 5, 2025 at 9:18 PM
Looking forward to this tomorrow ⬇️
National #Mesothelioma Network Education Day
✅ New Management Guideline
🩻 New Staging (TNM 9)
📈 Review of Audit Performance (QPI)
Plus Trials, Interventional Pain, Pleural Nursing & Horizon scanning
…then, dinner with team 🎉🍷
National #Mesothelioma Network Education Day
✅ New Management Guideline
🩻 New Staging (TNM 9)
📈 Review of Audit Performance (QPI)
Plus Trials, Interventional Pain, Pleural Nursing & Horizon scanning
…then, dinner with team 🎉🍷
Reposted by Kevin Blyth
Check out this interview with our #PREDICTMeso PI @kevingblyth.bsky.social discussing #mesothelioma; why it takes so long to develop, and what we at @predict-meso.bsky.social are doing to research and develop new treatments
#MesotheliomaResearch #MesoORIGINS #CancerResearch #EarlyDetection
#MesotheliomaResearch #MesoORIGINS #CancerResearch #EarlyDetection
A few mins of #Mesothelioma chat starts @1251 on BBC Scotland Lunchtime Live👇
Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?
@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org
www.bbc.co.uk/sounds/play/...
Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?
@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org
www.bbc.co.uk/sounds/play/...
Lunchtime Live - 23/12/2024 - BBC Sounds
News updates from Scotland and beyond, plus all your lunchtime sport, travel and weather.
www.bbc.co.uk
January 6, 2025 at 3:05 PM
Check out this interview with our #PREDICTMeso PI @kevingblyth.bsky.social discussing #mesothelioma; why it takes so long to develop, and what we at @predict-meso.bsky.social are doing to research and develop new treatments
#MesotheliomaResearch #MesoORIGINS #CancerResearch #EarlyDetection
#MesotheliomaResearch #MesoORIGINS #CancerResearch #EarlyDetection
A few mins of #Mesothelioma chat starts @1251 on BBC Scotland Lunchtime Live👇
Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?
@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org
www.bbc.co.uk/sounds/play/...
Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?
@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org
www.bbc.co.uk/sounds/play/...
Lunchtime Live - 23/12/2024 - BBC Sounds
News updates from Scotland and beyond, plus all your lunchtime sport, travel and weather.
www.bbc.co.uk
December 23, 2024 at 7:02 PM
A few mins of #Mesothelioma chat starts @1251 on BBC Scotland Lunchtime Live👇
Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?
@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org
www.bbc.co.uk/sounds/play/...
Why does meso develop decades after exposure?
What are we doing in @predict-meso.bsky.social to develop new treatments?
@uofglasgow.bsky.social
@cruk-si.bsky.social
@cancerresearchuk.org
www.bbc.co.uk/sounds/play/...
Looking forward to talking #mesothelioma on BBC Scotland Lunchtime Live in a few minutes!
December 23, 2024 at 12:49 PM
Looking forward to talking #mesothelioma on BBC Scotland Lunchtime Live in a few minutes!
Reposted by Kevin Blyth
There are now 24 step-by-step guides, explaining how to create these ⬇️ data visualizations with R/ggplot2 - I hope this is a useful resource. Find them all here: joachimgoedhart.github.io/DataViz-prot...
December 16, 2024 at 9:25 AM
There are now 24 step-by-step guides, explaining how to create these ⬇️ data visualizations with R/ggplot2 - I hope this is a useful resource. Find them all here: joachimgoedhart.github.io/DataViz-prot...
Article in @heraldscotland.bsky.social this week highlights a sad #mesothelioma story & ongoing research in PREDICT-Meso, IAMMED, Meso-SCAPE & excellent Hansen lab
@predict-meso.bsky.social
@djmurphylab2.bsky.social
@cruk-si.bsky.social
www.heraldscotland.com/news/2477596...
@predict-meso.bsky.social
@djmurphylab2.bsky.social
@cruk-si.bsky.social
www.heraldscotland.com/news/2477596...
Deadly dust stole my husband: fears grow for asbestos crisis in Scotland's buildings
They met as teenagers, married young, raised their family and saved hard for the future.
www.heraldscotland.com
December 11, 2024 at 8:23 PM
Article in @heraldscotland.bsky.social this week highlights a sad #mesothelioma story & ongoing research in PREDICT-Meso, IAMMED, Meso-SCAPE & excellent Hansen lab
@predict-meso.bsky.social
@djmurphylab2.bsky.social
@cruk-si.bsky.social
www.heraldscotland.com/news/2477596...
@predict-meso.bsky.social
@djmurphylab2.bsky.social
@cruk-si.bsky.social
www.heraldscotland.com/news/2477596...
It was great to be part of the BTOG/MesoUK Essential Update meeting this week
Topics included diagnostics, new Rx, CNS roles, legal, pleural
Nice to see 2 current PhD students presenting
🏴 Meso Network (Matt)
🧬 PREDICT-Meso (Mark)
@btog.bsky.social
@mesouk.bsky.social
@uofglasgow.bsky.social
Topics included diagnostics, new Rx, CNS roles, legal, pleural
Nice to see 2 current PhD students presenting
🏴 Meso Network (Matt)
🧬 PREDICT-Meso (Mark)
@btog.bsky.social
@mesouk.bsky.social
@uofglasgow.bsky.social
December 11, 2024 at 7:50 PM
It was great to be part of the BTOG/MesoUK Essential Update meeting this week
Topics included diagnostics, new Rx, CNS roles, legal, pleural
Nice to see 2 current PhD students presenting
🏴 Meso Network (Matt)
🧬 PREDICT-Meso (Mark)
@btog.bsky.social
@mesouk.bsky.social
@uofglasgow.bsky.social
Topics included diagnostics, new Rx, CNS roles, legal, pleural
Nice to see 2 current PhD students presenting
🏴 Meso Network (Matt)
🧬 PREDICT-Meso (Mark)
@btog.bsky.social
@mesouk.bsky.social
@uofglasgow.bsky.social
Very proud of Jenny Ferguson - PhD viva passed today! 🎉🥂
Her thesis on stratification of #respiratory disease covered
🫁 STRATIFY trial of #pleural staging in Lung Ca
🔬Predictive Markers in #MPE
🦠 Immune markers of severe #COVID19
🙏 R Bhatnagar, C Church & L Richmond!
@uofglasgow.bsky.social
Her thesis on stratification of #respiratory disease covered
🫁 STRATIFY trial of #pleural staging in Lung Ca
🔬Predictive Markers in #MPE
🦠 Immune markers of severe #COVID19
🙏 R Bhatnagar, C Church & L Richmond!
@uofglasgow.bsky.social
December 11, 2024 at 7:19 PM
Very proud of Jenny Ferguson - PhD viva passed today! 🎉🥂
Her thesis on stratification of #respiratory disease covered
🫁 STRATIFY trial of #pleural staging in Lung Ca
🔬Predictive Markers in #MPE
🦠 Immune markers of severe #COVID19
🙏 R Bhatnagar, C Church & L Richmond!
@uofglasgow.bsky.social
Her thesis on stratification of #respiratory disease covered
🫁 STRATIFY trial of #pleural staging in Lung Ca
🔬Predictive Markers in #MPE
🦠 Immune markers of severe #COVID19
🙏 R Bhatnagar, C Church & L Richmond!
@uofglasgow.bsky.social
Reposted by Kevin Blyth
🟡 Recruiting now – PREDICT-Meso PPI Group
People affected my mesothelioma to join a new PPI group to advise on all stages of mesothelioma research.
Message us or visit our website… www.researchforthefuture.org/studies/predict-meso
People affected my mesothelioma to join a new PPI group to advise on all stages of mesothelioma research.
Message us or visit our website… www.researchforthefuture.org/studies/predict-meso
January 19, 2024 at 4:03 PM
🟡 Recruiting now – PREDICT-Meso PPI Group
People affected my mesothelioma to join a new PPI group to advise on all stages of mesothelioma research.
Message us or visit our website… www.researchforthefuture.org/studies/predict-meso
People affected my mesothelioma to join a new PPI group to advise on all stages of mesothelioma research.
Message us or visit our website… www.researchforthefuture.org/studies/predict-meso
New paper from our group on body composition changes in #mesothelioma during chemo ⬇️
💪 61.5% patients lost muscle
🧈 60.4% patients lost fat
🫁 Extreme thoracic muscle loss & total fat loss independently prognostic
Funded by Asthma+Lung UK
www.sciencedirect.com/science/arti...
💪 61.5% patients lost muscle
🧈 60.4% patients lost fat
🫁 Extreme thoracic muscle loss & total fat loss independently prognostic
Funded by Asthma+Lung UK
www.sciencedirect.com/science/arti...
The prevalence and prognostic significance of Sarcopenia and Adipopenia in Pleural Mesothelioma
Altered body composition is associated with adverse survival in multiple cancers. We determined the prevalence, prognostic significance and clinicopat…
www.sciencedirect.com
December 10, 2024 at 8:53 PM
New paper from our group on body composition changes in #mesothelioma during chemo ⬇️
💪 61.5% patients lost muscle
🧈 60.4% patients lost fat
🫁 Extreme thoracic muscle loss & total fat loss independently prognostic
Funded by Asthma+Lung UK
www.sciencedirect.com/science/arti...
💪 61.5% patients lost muscle
🧈 60.4% patients lost fat
🫁 Extreme thoracic muscle loss & total fat loss independently prognostic
Funded by Asthma+Lung UK
www.sciencedirect.com/science/arti...
Reposted by Kevin Blyth
Kevin Blyth: management of mesothelioma effusion
🔹IPC vs pleurodesis = equivalent efficacy
For pleurodesis:
🔹 Talc = most effective agent
🔹 Big drain no better than smaller ones
🔹 NSAIDs fine for analgesia (won’t limit pleurodesis)
🔹 Talc slurry as good as poudrage
🔹IPC vs pleurodesis = equivalent efficacy
For pleurodesis:
🔹 Talc = most effective agent
🔹 Big drain no better than smaller ones
🔹 NSAIDs fine for analgesia (won’t limit pleurodesis)
🔹 Talc slurry as good as poudrage
December 9, 2024 at 3:57 PM
Kevin Blyth: management of mesothelioma effusion
🔹IPC vs pleurodesis = equivalent efficacy
For pleurodesis:
🔹 Talc = most effective agent
🔹 Big drain no better than smaller ones
🔹 NSAIDs fine for analgesia (won’t limit pleurodesis)
🔹 Talc slurry as good as poudrage
🔹IPC vs pleurodesis = equivalent efficacy
For pleurodesis:
🔹 Talc = most effective agent
🔹 Big drain no better than smaller ones
🔹 NSAIDs fine for analgesia (won’t limit pleurodesis)
🔹 Talc slurry as good as poudrage
Reposted by Kevin Blyth
@dean_fennell: 2L mesothelioma options
👉 (small) subset of non-epithelioid pts do very well with Vin
🟢 Gem+Ramucirumab = ⬆️ PFS
❓ Gem maintenance = ⬆️ PFS, but a bit forgotten
🟢 Platinum rechallenge RR 50%
❓Activity in immuno rechallenge, RR up to 50%
👉 (small) subset of non-epithelioid pts do very well with Vin
🟢 Gem+Ramucirumab = ⬆️ PFS
❓ Gem maintenance = ⬆️ PFS, but a bit forgotten
🟢 Platinum rechallenge RR 50%
❓Activity in immuno rechallenge, RR up to 50%
December 9, 2024 at 12:50 PM
@dean_fennell: 2L mesothelioma options
👉 (small) subset of non-epithelioid pts do very well with Vin
🟢 Gem+Ramucirumab = ⬆️ PFS
❓ Gem maintenance = ⬆️ PFS, but a bit forgotten
🟢 Platinum rechallenge RR 50%
❓Activity in immuno rechallenge, RR up to 50%
👉 (small) subset of non-epithelioid pts do very well with Vin
🟢 Gem+Ramucirumab = ⬆️ PFS
❓ Gem maintenance = ⬆️ PFS, but a bit forgotten
🟢 Platinum rechallenge RR 50%
❓Activity in immuno rechallenge, RR up to 50%
Reposted by Kevin Blyth
Improve your mesothelioma service by forming a network: the 🏴 experience by Matthew Tate
🟢 ⬆️ data completeness
🟢 ⬇️ non-biopsy cases
🟢 ⬆️ OS in non-epithelioid
🔺 OS benefit not solely due to arrival of immunotherapy
@btog.bsky.social
@mesouk.bsky.social
🟢 ⬆️ data completeness
🟢 ⬇️ non-biopsy cases
🟢 ⬆️ OS in non-epithelioid
🔺 OS benefit not solely due to arrival of immunotherapy
@btog.bsky.social
@mesouk.bsky.social
December 9, 2024 at 9:48 AM
Improve your mesothelioma service by forming a network: the 🏴 experience by Matthew Tate
🟢 ⬆️ data completeness
🟢 ⬇️ non-biopsy cases
🟢 ⬆️ OS in non-epithelioid
🔺 OS benefit not solely due to arrival of immunotherapy
@btog.bsky.social
@mesouk.bsky.social
🟢 ⬆️ data completeness
🟢 ⬇️ non-biopsy cases
🟢 ⬆️ OS in non-epithelioid
🔺 OS benefit not solely due to arrival of immunotherapy
@btog.bsky.social
@mesouk.bsky.social
Reposted by Kevin Blyth
PREDICT-Meso:
🧐 How does inflammation evolve into malignancy?
🧐 Can we diagnose mesothelioma at pre-malignant stage?
👉 80 institutions, 16 countries
👉 x5 work streams
Fantastic, ambitious, international, multi-faceted project
@btog.bsky.social
@mesouk.bsky.social
🧐 How does inflammation evolve into malignancy?
🧐 Can we diagnose mesothelioma at pre-malignant stage?
👉 80 institutions, 16 countries
👉 x5 work streams
Fantastic, ambitious, international, multi-faceted project
@btog.bsky.social
@mesouk.bsky.social
December 9, 2024 at 10:32 AM
PREDICT-Meso:
🧐 How does inflammation evolve into malignancy?
🧐 Can we diagnose mesothelioma at pre-malignant stage?
👉 80 institutions, 16 countries
👉 x5 work streams
Fantastic, ambitious, international, multi-faceted project
@btog.bsky.social
@mesouk.bsky.social
🧐 How does inflammation evolve into malignancy?
🧐 Can we diagnose mesothelioma at pre-malignant stage?
👉 80 institutions, 16 countries
👉 x5 work streams
Fantastic, ambitious, international, multi-faceted project
@btog.bsky.social
@mesouk.bsky.social
Matthew Tate presenting outcomes from the Scottish #Mesothelioma Network
⬆️ Overall Survival in Non-Epi cases
⬆️ Use of Immunotherapy
⬆️ OS in Non-Epi cases not receiving IO
Mesothelioma networks should be developed across the UK
⬆️ Overall Survival in Non-Epi cases
⬆️ Use of Immunotherapy
⬆️ OS in Non-Epi cases not receiving IO
Mesothelioma networks should be developed across the UK
December 9, 2024 at 9:57 AM
Matthew Tate presenting outcomes from the Scottish #Mesothelioma Network
⬆️ Overall Survival in Non-Epi cases
⬆️ Use of Immunotherapy
⬆️ OS in Non-Epi cases not receiving IO
Mesothelioma networks should be developed across the UK
⬆️ Overall Survival in Non-Epi cases
⬆️ Use of Immunotherapy
⬆️ OS in Non-Epi cases not receiving IO
Mesothelioma networks should be developed across the UK
Reposted by Kevin Blyth
Was that a collective sigh of relief, I heard?
We have an early Christmas present for you all - we've extended the #BTOG25 abstract submission deadline!
You now have until Monday 16th December 23:59 GMT - no further extension will be made.
Definitely a gift you can open before December 25th!
Full details www.btog.org/23rd-btog-an...
#LCSM
You now have until Monday 16th December 23:59 GMT - no further extension will be made.
Definitely a gift you can open before December 25th!
Full details www.btog.org/23rd-btog-an...
#LCSM
December 4, 2024 at 12:34 PM
Was that a collective sigh of relief, I heard?
On-call week for me at #QEUH Lots of Flu A! 🦠😷 Felt like every other patient today.
Will be interested to see if the upward trend in last weeks numbers continues publichealthscotland.scot/publications...
Will be interested to see if the upward trend in last weeks numbers continues publichealthscotland.scot/publications...
Viral respiratory diseases (including influenza and COVID-19) in Scotland surveillance report 28 November 2024 - Viral respiratory diseases (including influenza and COVID-19) in Scotland surveillance ...
publichealthscotland.scot
December 4, 2024 at 6:51 PM
On-call week for me at #QEUH Lots of Flu A! 🦠😷 Felt like every other patient today.
Will be interested to see if the upward trend in last weeks numbers continues publichealthscotland.scot/publications...
Will be interested to see if the upward trend in last weeks numbers continues publichealthscotland.scot/publications...
Reposted by Kevin Blyth
Can you believe it, it’s almost December! This year we’re excited to bring you a #RespMas advent calendar! Every day we’ll open a window to reveal a paper worth reading! By Christmas we’ll all be on top of our Respiratory game! #medsky #pulmsky #lungsky #RespEd #RespIsBest
November 30, 2024 at 7:26 PM
Reposted by Kevin Blyth
This is why we are all in this field…to see, and one day to be able to produce work like this.
Patho-DBiT-seq
www.cell.com/cell/fulltex...
Patho-DBiT-seq
www.cell.com/cell/fulltex...
Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues
Patho-DBiT enables spatial profiling of a range of RNA species (i.e., mRNA, microRNA,
tRNA, splicing isoform, etc.) all at once in clinical formalin-fixed paraffin-embedded
tissue with high sensitivit...
www.cell.com
November 29, 2024 at 11:35 PM
This is why we are all in this field…to see, and one day to be able to produce work like this.
Patho-DBiT-seq
www.cell.com/cell/fulltex...
Patho-DBiT-seq
www.cell.com/cell/fulltex...
Heading home after a fantastic #BTSWinter2024 Leaving energised and grateful for friends and the opportunity to talk #mesothelioma in the Plenary Scientific Symposium. Also excited for 2025 under our new BTS President!
November 29, 2024 at 6:11 PM
Heading home after a fantastic #BTSWinter2024 Leaving energised and grateful for friends and the opportunity to talk #mesothelioma in the Plenary Scientific Symposium. Also excited for 2025 under our new BTS President!
This morning I presented results of the STRATIFY multi-centre trial of staging thoracoscopy for minimal pleural effusion in lung cancer. The prevalence of occult pleural mets was only 14%, thoracoscopy was safe & altered treatment plans. Paper coming soon! #BTSWinter2024
x.com/UKPleura/sta...
x.com/UKPleura/sta...
November 28, 2024 at 2:41 PM
This morning I presented results of the STRATIFY multi-centre trial of staging thoracoscopy for minimal pleural effusion in lung cancer. The prevalence of occult pleural mets was only 14%, thoracoscopy was safe & altered treatment plans. Paper coming soon! #BTSWinter2024
x.com/UKPleura/sta...
x.com/UKPleura/sta...
I'm very grateful to Asthma & Lung UK for the early support they provided to our now international #mesothelioma research program. Pump-priming is such an impactful strategy for grant-awarding charities x.com/IanJarroldAL...
x.com
x.com
November 28, 2024 at 2:31 PM
I'm very grateful to Asthma & Lung UK for the early support they provided to our now international #mesothelioma research program. Pump-priming is such an impactful strategy for grant-awarding charities x.com/IanJarroldAL...