Katie Gillies
@katiegillies.bsky.social
Professor of Clinical Trials Methodology & MRC Senior Non-Clinical Fellow. Mixed-methods. Generating evidence to inform design and delivery of participant centred trials using behavioural science.
This time next year we will be wrapping up #ICTMC2026 in Birmingham. I'm already starting to think through ideas for abstracts. What trials methods research do you hope to hear about/present at the conference?
ictmc.org
ictmc.org
ICTMC 2026 – International Clinical Trials Methodology Conference
ictmc.org
September 18, 2025 at 12:32 PM
This time next year we will be wrapping up #ICTMC2026 in Birmingham. I'm already starting to think through ideas for abstracts. What trials methods research do you hope to hear about/present at the conference?
ictmc.org
ictmc.org
Reposted by Katie Gillies
*New publication*
Interventions to support patient decision making about taking part in health research: A systematic review
doi.org/10.1016/j.pe...
Just out in Patient Education & Counseling
@sydneyhealthliteracylab.org.au @katiegillies.bsky.social
Interventions to support patient decision making about taking part in health research: A systematic review
doi.org/10.1016/j.pe...
Just out in Patient Education & Counseling
@sydneyhealthliteracylab.org.au @katiegillies.bsky.social
September 12, 2025 at 1:47 AM
*New publication*
Interventions to support patient decision making about taking part in health research: A systematic review
doi.org/10.1016/j.pe...
Just out in Patient Education & Counseling
@sydneyhealthliteracylab.org.au @katiegillies.bsky.social
Interventions to support patient decision making about taking part in health research: A systematic review
doi.org/10.1016/j.pe...
Just out in Patient Education & Counseling
@sydneyhealthliteracylab.org.au @katiegillies.bsky.social
@anniestats.bsky.social gave a great talk on decentralised trials. Main message from PhD review work is there isn't a one size fits all approach. Trial design may need to be contextually determined and responsive to population needs #SCT2025
May 21, 2025 at 4:15 PM
@anniestats.bsky.social gave a great talk on decentralised trials. Main message from PhD review work is there isn't a one size fits all approach. Trial design may need to be contextually determined and responsive to population needs #SCT2025
@liamhbishophealth.bsky.social kicks off his talk at #SCT2025 by thanking the Society for continuing to create space for raising EDI issues in clinical trials through recognition across sessions and committees. And gives a great talk on building trust through community focussed workshops and videos.
May 21, 2025 at 3:37 PM
@liamhbishophealth.bsky.social kicks off his talk at #SCT2025 by thanking the Society for continuing to create space for raising EDI issues in clinical trials through recognition across sessions and committees. And gives a great talk on building trust through community focussed workshops and videos.
Using imp sci to consider how actionable regulatory guidance is for diversity in clinical trials. Rebecca Metcalfe highlights that more work is needed to make system-level changes to where and how trials are conducted. Building trusted relationships & enforcing guidance are key next steps #SCT2025
May 21, 2025 at 3:18 PM
Using imp sci to consider how actionable regulatory guidance is for diversity in clinical trials. Rebecca Metcalfe highlights that more work is needed to make system-level changes to where and how trials are conducted. Building trusted relationships & enforcing guidance are key next steps #SCT2025
If you want more trials methods research post #SCT2025 please do come to #ICTMC2026 in Birmingham UK 14-17 September. More here ictmc.org
May 20, 2025 at 7:28 PM
If you want more trials methods research post #SCT2025 please do come to #ICTMC2026 in Birmingham UK 14-17 September. More here ictmc.org
Adwoa Parker walking us through the update of the Cochrane review on interventions to improve recruitment. 7 years & >50 new studies doesn't tell us much more with high certainty. Suggests trialists think carefully about using interventions with no effect (bottom 3 in pic) #SCT2025
May 20, 2025 at 5:20 PM
Adwoa Parker walking us through the update of the Cochrane review on interventions to improve recruitment. 7 years & >50 new studies doesn't tell us much more with high certainty. Suggests trialists think carefully about using interventions with no effect (bottom 3 in pic) #SCT2025
Founders Lecture #SCT2025 on DMCs - Thomas Fleming flags the @nihr.bsky.social funded DAMOCLES study that developed a charter for DMCs to support them to do their jobs well. Full paper here www.thelancet.com/journals/lan...
A proposed charter for clinical trial data monitoring committees: helping them to do their job well
Formal monitoring of data from randomised controlled trials (RCTs) is becoming more
common. Wide variation exists in the structure and organisation of data monitoring
committees (DMCs), with little gu...
www.thelancet.com
May 20, 2025 at 3:52 PM
Founders Lecture #SCT2025 on DMCs - Thomas Fleming flags the @nihr.bsky.social funded DAMOCLES study that developed a charter for DMCs to support them to do their jobs well. Full paper here www.thelancet.com/journals/lan...
Reposted by Katie Gillies
See how we can enable lower carbon clinical trials without compromising health outcomes. UCD, University of Liverpool, University of Galway, ICR, the HRB-TMRN, MRC-NIHR TMRP & PPI partners, co-developed this video about Greener Trials. www.youtube.com/watch?v=LbgG... #internationalclinicaltrialsday
Greener Trials
YouTube video by UCD Medicine
www.youtube.com
May 20, 2025 at 2:05 PM
See how we can enable lower carbon clinical trials without compromising health outcomes. UCD, University of Liverpool, University of Galway, ICR, the HRB-TMRN, MRC-NIHR TMRP & PPI partners, co-developed this video about Greener Trials. www.youtube.com/watch?v=LbgG... #internationalclinicaltrialsday
Reposted by Katie Gillies
From development to delivery, it takes a collaborative multidisciplinary team to make a clinical trial successful.
Find out more about how Clinical Trials Units make research happen here: ukcrc-ctu.org.uk
#ICTD2025 #ClinicalTrials #CTD2025
Find out more about how Clinical Trials Units make research happen here: ukcrc-ctu.org.uk
#ICTD2025 #ClinicalTrials #CTD2025
May 20, 2025 at 1:40 PM
From development to delivery, it takes a collaborative multidisciplinary team to make a clinical trial successful.
Find out more about how Clinical Trials Units make research happen here: ukcrc-ctu.org.uk
#ICTD2025 #ClinicalTrials #CTD2025
Find out more about how Clinical Trials Units make research happen here: ukcrc-ctu.org.uk
#ICTD2025 #ClinicalTrials #CTD2025
Reposted by Katie Gillies
#ClinicalTrialsDay is the time to consider how to ensure the environmental sustainability of clinical trials. Read our @frankskyou.bsky.social write about why and how greener trials serve the purpose of benefiting the coming generations on SpringerNature blog: bit.ly/4moCL11
Towards Greener Trials
In celebration of International Clinical Trials Day, which this year has a sub-theme around ‘benefiting generations to come’, Frank Sui-keung You from the University of Aberdeen explains why our plane...
communities.springernature.com
May 20, 2025 at 2:48 PM
#ClinicalTrialsDay is the time to consider how to ensure the environmental sustainability of clinical trials. Read our @frankskyou.bsky.social write about why and how greener trials serve the purpose of benefiting the coming generations on SpringerNature blog: bit.ly/4moCL11
My highlight from #SCT2025 day 1 was Mollie Paynes talk on her PhD research on dose-response methodology in complex intervention trials. It's always great to hear a statistics talk that non-statisticians can also follow. Perfectly pitched. More on Mollies work here github.com/molliejpayne...
May 19, 2025 at 11:28 PM
My highlight from #SCT2025 day 1 was Mollie Paynes talk on her PhD research on dose-response methodology in complex intervention trials. It's always great to hear a statistics talk that non-statisticians can also follow. Perfectly pitched. More on Mollies work here github.com/molliejpayne...
Reposted by Katie Gillies
Tomorrow isn’t just International Clinical Trials Day.
Keep your eyes peeled for the launch of our strategy for 2025 – 2030!
#UKCTUNetwork #CTUNetworkStrategy
Keep your eyes peeled for the launch of our strategy for 2025 – 2030!
#UKCTUNetwork #CTUNetworkStrategy
May 19, 2025 at 2:56 PM
Tomorrow isn’t just International Clinical Trials Day.
Keep your eyes peeled for the launch of our strategy for 2025 – 2030!
#UKCTUNetwork #CTUNetworkStrategy
Keep your eyes peeled for the launch of our strategy for 2025 – 2030!
#UKCTUNetwork #CTUNetworkStrategy
Late breaking session at #SCT2025 on the impact of recent US govt actions. So important for us to come together as a trials community to collectively support the research endeavour and our US colleagues. Flags an opinion piece in @nytimes.com today that encourages us to 'get mad in public'
May 19, 2025 at 9:10 PM
Late breaking session at #SCT2025 on the impact of recent US govt actions. So important for us to come together as a trials community to collectively support the research endeavour and our US colleagues. Flags an opinion piece in @nytimes.com today that encourages us to 'get mad in public'
There is a need for trials methodology research for trials designed & delivered in the global south. Sangeetha Paramasivan flags article on need for this work in RCTs in India & talks through adaptation of quintet recruitment intervention in this setting #SCT2025 www.thelancet.com/journals/lan...
Trials Methodology Research: what is it and why should India invest in it?
This Viewpoint presents an overview of trials methodology research (TMR) and the case
for investing in TMR in India. Randomised controlled trials and other types of clinical
research inform evidence-b...
www.thelancet.com
May 19, 2025 at 5:29 PM
There is a need for trials methodology research for trials designed & delivered in the global south. Sangeetha Paramasivan flags article on need for this work in RCTs in India & talks through adaptation of quintet recruitment intervention in this setting #SCT2025 www.thelancet.com/journals/lan...
Arun Sanyal giving the Curtis Meinert Keynote @ #SCT2025 talks us through the use of Desirability of Outcome Ranking (DOOR) in liver trials. Makes a suggestion for pan-specialty #CoreOutcomeSets to facilitate DOOR integration in evidence synthesis for intersecting clinical contexts.
May 19, 2025 at 4:23 PM
Arun Sanyal giving the Curtis Meinert Keynote @ #SCT2025 talks us through the use of Desirability of Outcome Ranking (DOOR) in liver trials. Makes a suggestion for pan-specialty #CoreOutcomeSets to facilitate DOOR integration in evidence synthesis for intersecting clinical contexts.
One of our PhD students, Mojca Cerar, is running a survey to understand how recruitment & retention data in trials is communicated with trial sites. If you have any role in this process please complete our 10 min survey. We only have 23 responses with 2 weeks to go! forms.office.com/e/9RCxiiCXM2
April 15, 2025 at 9:24 AM
One of our PhD students, Mojca Cerar, is running a survey to understand how recruitment & retention data in trials is communicated with trial sites. If you have any role in this process please complete our 10 min survey. We only have 23 responses with 2 weeks to go! forms.office.com/e/9RCxiiCXM2
Reposted by Katie Gillies
NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the @bmj.com @jama.com , @thelancet.bsky.social, @plos.org and @naturemedicine.bsky.social
—> www.bmj.com/content/389/...
#openscience #transparency #medsky #statssky #episky
—> www.bmj.com/content/389/...
#openscience #transparency #medsky #statssky #episky
April 15, 2025 at 5:55 AM
NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the @bmj.com @jama.com , @thelancet.bsky.social, @plos.org and @naturemedicine.bsky.social
—> www.bmj.com/content/389/...
#openscience #transparency #medsky #statssky #episky
—> www.bmj.com/content/389/...
#openscience #transparency #medsky #statssky #episky
Reposted by Katie Gillies
Improving how we approach informing people about the potential risks and benefits of trial interventions.
trialsjournal.biomedcentral.com/articles/10....
trialsjournal.biomedcentral.com/articles/10....
Variation in the extent to which patient information leaflets describe potential benefits and harms of trial interventions: a commentary - Trials
Clinical trial participants must understand the possible risks and benefits of trial interventions before providing their informed consent to participate. The aim of this commentary is twofold: to sum...
trialsjournal.biomedcentral.com
April 15, 2025 at 8:57 AM
Improving how we approach informing people about the potential risks and benefits of trial interventions.
trialsjournal.biomedcentral.com/articles/10....
trialsjournal.biomedcentral.com/articles/10....
Reposted by Katie Gillies
If you are doing work on equity, diversity and inclusion in randomised controlled trials, the journal Trials has a special series you could submit to:
www.biomedcentral.com/collections/...
Deadline end of June, and articles can be original research, commentary, education but not protocols.
www.biomedcentral.com/collections/...
Deadline end of June, and articles can be original research, commentary, education but not protocols.
February 14, 2025 at 8:06 AM
If you are doing work on equity, diversity and inclusion in randomised controlled trials, the journal Trials has a special series you could submit to:
www.biomedcentral.com/collections/...
Deadline end of June, and articles can be original research, commentary, education but not protocols.
www.biomedcentral.com/collections/...
Deadline end of June, and articles can be original research, commentary, education but not protocols.
Reposted by Katie Gillies
Trial participant self‑reported understanding of randomisation phrases in participant info can be high but acceptability of some descriptions is low esp if linked to gambling/luck
@streweek.bsky.social @katiegillies.bsky.social @taliaisaacs.bsky.social
trialsjournal.biomedcentral.com/articles/10....
@streweek.bsky.social @katiegillies.bsky.social @taliaisaacs.bsky.social
trialsjournal.biomedcentral.com/articles/10....
Trial participants’ self-reported understanding of randomisation phrases in participation information leaflets can be high, but acceptability of some descriptions is low, especially those linked to ga...
Background Evidence indicates that trial participants often struggle to understand participant information leaflets (PILs) for clinical trials, including the concept of randomisation. We analysed the ...
trialsjournal.biomedcentral.com
February 20, 2025 at 3:48 AM
Trial participant self‑reported understanding of randomisation phrases in participant info can be high but acceptability of some descriptions is low esp if linked to gambling/luck
@streweek.bsky.social @katiegillies.bsky.social @taliaisaacs.bsky.social
trialsjournal.biomedcentral.com/articles/10....
@streweek.bsky.social @katiegillies.bsky.social @taliaisaacs.bsky.social
trialsjournal.biomedcentral.com/articles/10....
Currently low response rates from CTU Directors (n=5), Programmers/Data Managers (n=0), & QA Managers (n=3) working in clinical trials. We need to know what these groups think the challenges are for greener trials.
forms.office.com/e/fkeLD8HbMA
Please complete &RT
@ukctunetwork.bsky.social
forms.office.com/e/fkeLD8HbMA
Please complete &RT
@ukctunetwork.bsky.social
February 12, 2025 at 8:59 AM
Currently low response rates from CTU Directors (n=5), Programmers/Data Managers (n=0), & QA Managers (n=3) working in clinical trials. We need to know what these groups think the challenges are for greener trials.
forms.office.com/e/fkeLD8HbMA
Please complete &RT
@ukctunetwork.bsky.social
forms.office.com/e/fkeLD8HbMA
Please complete &RT
@ukctunetwork.bsky.social
We now have 71 responses but need more if we are to identify the key challenges for the design and delivery of greener trials.
Please complete and share onwards. Average completion time is only 12mins. We need to hear from you.
forms.office.com/e/fkeLD8HbMA
Thank you
Please complete and share onwards. Average completion time is only 12mins. We need to hear from you.
forms.office.com/e/fkeLD8HbMA
Thank you
February 5, 2025 at 9:52 AM
We now have 71 responses but need more if we are to identify the key challenges for the design and delivery of greener trials.
Please complete and share onwards. Average completion time is only 12mins. We need to hear from you.
forms.office.com/e/fkeLD8HbMA
Thank you
Please complete and share onwards. Average completion time is only 12mins. We need to hear from you.
forms.office.com/e/fkeLD8HbMA
Thank you
Do you work on clinical trials?
We need your help to understand the challenges to designing & delivering greener trials. Only 30 responses so far but we can all have a say on this topic. Please take 10 minutes to tell us what you think tinyurl.com/GreenTrials
Please share across your networks
We need your help to understand the challenges to designing & delivering greener trials. Only 30 responses so far but we can all have a say on this topic. Please take 10 minutes to tell us what you think tinyurl.com/GreenTrials
Please share across your networks
Microsoft Forms
tinyurl.com
January 21, 2025 at 8:40 AM
Do you work on clinical trials?
We need your help to understand the challenges to designing & delivering greener trials. Only 30 responses so far but we can all have a say on this topic. Please take 10 minutes to tell us what you think tinyurl.com/GreenTrials
Please share across your networks
We need your help to understand the challenges to designing & delivering greener trials. Only 30 responses so far but we can all have a say on this topic. Please take 10 minutes to tell us what you think tinyurl.com/GreenTrials
Please share across your networks
Great 1st paper from Frank You's PhD👏
Review headline-Much of the carbon in trials is associated with human behaviour. We found no studies investigating determinants of these behaviours. Soon to launch survey will help us fill this gap to make our trials greener.
papers.ssrn.com/sol3/papers....
Review headline-Much of the carbon in trials is associated with human behaviour. We found no studies investigating determinants of these behaviours. Soon to launch survey will help us fill this gap to make our trials greener.
papers.ssrn.com/sol3/papers....
Carbon Emissions Associated with Clinical Trials: A Scoping Review
ObjectivesTo review and synthesise available evidence on carbon emissions associated with clinical trials to inform future research on design and delivery of gr
papers.ssrn.com
December 12, 2024 at 1:42 PM
Great 1st paper from Frank You's PhD👏
Review headline-Much of the carbon in trials is associated with human behaviour. We found no studies investigating determinants of these behaviours. Soon to launch survey will help us fill this gap to make our trials greener.
papers.ssrn.com/sol3/papers....
Review headline-Much of the carbon in trials is associated with human behaviour. We found no studies investigating determinants of these behaviours. Soon to launch survey will help us fill this gap to make our trials greener.
papers.ssrn.com/sol3/papers....