Katie Solari
kasolari.bsky.social
Katie Solari
@kasolari.bsky.social
Research scientist at Stanford and Associate Director of Genomics for the Stanford Program for Conservation Genomics
Reposted by Katie Solari
Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n)
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 11, 2025 at 5:15 PM
Reposted by Katie Solari
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.

www.biorxiv.org/content/10.1...
Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation
The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and n...
www.biorxiv.org
October 22, 2025 at 5:46 PM
Snow leopards may vanish as warming hits fragile mountain habitats: www.earth.com/news/snow-le...
Snow leopards may vanish as warming hits fragile mountain habitats
Snow leopards across Asia share nearly identical genes, making them vulnerable to a rapidly warming planet.
www.earth.com
October 8, 2025 at 3:24 PM
Reposted by Katie Solari
Snow leopards show very low genetic diversity, a factor that may limit their ability to adapt to environmental changes and increase their risk of extinction. doi.org/g953dp
The world's snow leopards are very similar genetically—findings suggest that doesn't bode well for their future
There are relatively few snow leopards in the world, and it has likely been that way for a long time, a new study indicates.
phys.org
October 7, 2025 at 5:00 PM
Very excited to share that our work assessing the genomic diversity of snow leopards has come out today in PNAS! Spoiler alert - they have the lowest genetic diversity of all big cats!
www.pnas.org/doi/10.1073/...
news.stanford.edu/stories/2025...
@petrovadmitri.bsky.social @elliecat.bsky.social
Exceedingly low genetic diversity in snow leopards due to persistently small population size | PNAS
Snow leopards (Panthera uncia) serve as an umbrella species whose conservation benefits their high-elevation Asian habitat. Their numbers are belie...
www.pnas.org
October 7, 2025 at 9:10 PM
Reposted by Katie Solari
Snow leopards have the lowest genetic diversity of all big cats–a dubious distinction once held by cheetahs. It increases their risk of extinction in a warming climate. #Stanford-led #research #snowleopards @kasolari.bsky.social @petrovadmitri.bsky.social
news.stanford.edu/stories/2025...
Snow leopards’ low genetic diversity puts future at risk
A Stanford-led study reveals that snow leopards are the most genetically similar to each other among big cats, making them particularly vulnerable to drastic changes like the warming climate.
news.stanford.edu
October 7, 2025 at 5:32 PM
Reposted by Katie Solari
Happy that this paper - www.biorxiv.org/content/10.1... - was accepted at Mol Ecol Res and excited about the promise of this technology to measure pop sizes for such elusive species as snow leopards + learn about at least 1st-degree relationships + beyond? Congrats to Katie Solari and other authors!
Next-generation snow leopard population assessment tool: multiplex-PCR SNP panel for individual identification from feces
Snow leopards, Panthera uncia , are under threat from numerous pressures and are the focus of a great deal of conservation efforts. However, their elusive nature makes it difficult to estimate populat...
www.biorxiv.org
January 14, 2025 at 3:07 AM