Karl Biggs
@karlbiggs.bsky.social
Cell biologist passionate about microglia, lysosomes, and extracellular vesicles. My favorite protein is alpha synuclein.
UCLA [BS] -> Dartmouth[PhD] -> currently industry scientist in Boston.
UCLA [BS] -> Dartmouth[PhD] -> currently industry scientist in Boston.
Reposted by Karl Biggs
Hello imaging friends! Does anyone know a R/FR tag that is still somewhat bright after PFA+GA fixation? I need a two color experiment, and I am already using mEos4b for the G channel. Please RT!!
August 15, 2025 at 6:38 PM
Hello imaging friends! Does anyone know a R/FR tag that is still somewhat bright after PFA+GA fixation? I need a two color experiment, and I am already using mEos4b for the G channel. Please RT!!
Happy to share my main project from my PhD is published and on the cover of the Journal of Neuroscience!
If you’re interested in lysosomes, Parkinson’s Disease, neuroinflammation, or EVs it might have something in it for you!
www.jneurosci.org/content/45/1...
DM for the pdf if you need access!
If you’re interested in lysosomes, Parkinson’s Disease, neuroinflammation, or EVs it might have something in it for you!
www.jneurosci.org/content/45/1...
DM for the pdf if you need access!
Coronin1A Regulates the Trafficking of Alpha Synuclein in Microglia
Microglia respond to cytotoxic protein aggregates associated with the progression of neurodegenerative disease. Pathological protein aggregates activate the microglial NLRP3 inflammasome resulting in ...
www.jneurosci.org
March 13, 2025 at 1:10 PM
Happy to share my main project from my PhD is published and on the cover of the Journal of Neuroscience!
If you’re interested in lysosomes, Parkinson’s Disease, neuroinflammation, or EVs it might have something in it for you!
www.jneurosci.org/content/45/1...
DM for the pdf if you need access!
If you’re interested in lysosomes, Parkinson’s Disease, neuroinflammation, or EVs it might have something in it for you!
www.jneurosci.org/content/45/1...
DM for the pdf if you need access!
Reposted by Karl Biggs
Check out this fantastic new review on lysosome resilience mechanisms from a highly respected lysosomologist!
We've been studying mechanisms of resilience that protect lysosomes from damage and wrote a review on the topic. We consider lysosomal stress and damage on a spectrum. Please help me share as this is my first post 😀 and I don't have many followers! 🙏 Open Access: www.embopress.org/doi/full/10....
February 27, 2025 at 7:42 PM
Check out this fantastic new review on lysosome resilience mechanisms from a highly respected lysosomologist!
Reposted by Karl Biggs
📣 We are kicking off 2025 with a #LRRK2 webinar hosted by Luis Bonet Ponce, PhD from the Ohio State Department of Neurology at 1 pm ET. Mark your calendars!
📅 1/23
⏰ 1 pm ET
RSVP: us06web.zoom.us/meeting/regi...
📅 1/23
⏰ 1 pm ET
RSVP: us06web.zoom.us/meeting/regi...
January 17, 2025 at 5:29 PM
📣 We are kicking off 2025 with a #LRRK2 webinar hosted by Luis Bonet Ponce, PhD from the Ohio State Department of Neurology at 1 pm ET. Mark your calendars!
📅 1/23
⏰ 1 pm ET
RSVP: us06web.zoom.us/meeting/regi...
📅 1/23
⏰ 1 pm ET
RSVP: us06web.zoom.us/meeting/regi...
Reposted by Karl Biggs
The censorship algorithm on Twitter reduced our audience by roughly 95%, and seriously, who does that to a wildlife biology & advocacy group ?
So we moved 😇 over here to BlueSky
If you could, please help us regain our following
Follow
Retweet and
Repeat ;-)
Together we can change the world.
So we moved 😇 over here to BlueSky
If you could, please help us regain our following
Follow
Retweet and
Repeat ;-)
Together we can change the world.
January 4, 2025 at 5:56 PM
The censorship algorithm on Twitter reduced our audience by roughly 95%, and seriously, who does that to a wildlife biology & advocacy group ?
So we moved 😇 over here to BlueSky
If you could, please help us regain our following
Follow
Retweet and
Repeat ;-)
Together we can change the world.
So we moved 😇 over here to BlueSky
If you could, please help us regain our following
Follow
Retweet and
Repeat ;-)
Together we can change the world.