山元淳平/Junpei Yamamoto
@junpeiyamamoto.bsky.social
Associate Professor in Graduate School of Engineering Science, Osaka University, Japan.
Expertise: Nucleic Acids Chemistry, Photobiology, Structural biology.
Am always trying to conduct research that only I can do.
Expertise: Nucleic Acids Chemistry, Photobiology, Structural biology.
Am always trying to conduct research that only I can do.
Our collaborative work has been published in Communications Chemistry. Congrats to the co-authors!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Infrared and ultraviolet spectroscopic characterization of a key intermediate during DNA repair by (6-4) photolyase - Communications Chemistry
(6-4) photolyases repair carcinogenic pyrimidine(6-4)pyrimidone photoproducts, a process that requires two successive photons but whose mechanistic details remain elusive. Here, the authors use time-r...
www.nature.com
September 3, 2025 at 5:46 AM
Our collaborative work has been published in Communications Chemistry. Congrats to the co-authors!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by 山元淳平/Junpei Yamamoto
Tomoki Imura et al.: Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target? ##DNARepair##PhotocagedSubstrateAnaloga##HOgg1@osaka_univ_e...##IUCrhttps://journals.iucr.org/paper?S2052252525006062
Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target?
Engineered in crystallo photosensitivity in a DNA-repair enzyme is carefully assessed for its suitability as a target for time-resolved crystallographic studies.
journals.iucr.org
July 15, 2025 at 12:01 AM
Tomoki Imura et al.: Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target? ##DNARepair##PhotocagedSubstrateAnaloga##HOgg1@osaka_univ_e...##IUCrhttps://journals.iucr.org/paper?S2052252525006062
Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target? doi.org/10.1107/S205...
Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target?
Engineered in crystallo photosensitivity in a DNA-repair enzyme is carefully assessed for its suitability as a target for time-resolved crystallographic studies.
doi.org
July 15, 2025 at 1:39 AM
Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target? doi.org/10.1107/S205...
On the Thames
June 19, 2025 at 4:49 AM
On the Thames
Congrats for publication!🥳🎉Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography | Science Advances www.science.org/doi/10.1126/...
Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography
Time-resolved crystallography unveils how light-driven chromophore reduction sparks dramatic structural change in a photoreceptor.
www.science.org
May 16, 2025 at 8:52 PM
Congrats for publication!🥳🎉Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography | Science Advances www.science.org/doi/10.1126/...
Found that the smell of sterilized LB medium filled the hallway, so I checked the autoclave, but nothing wrong with it. When I took off my mask😷, the smell in the hallway disappeared. That means…🧐
December 24, 2024 at 8:07 AM
Found that the smell of sterilized LB medium filled the hallway, so I checked the autoclave, but nothing wrong with it. When I took off my mask😷, the smell in the hallway disappeared. That means…🧐
Fingerprint-targeting enrichment enabled us to capture new candidate proteins that bind non- canonical i-motif DNA structure. Published in Nucleic Acids Research!
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
Profiling of i-motif-binding proteins reveals functional roles of nucleolin in regulation of high-order DNA structures
Abstract. Non-canonical DNA structures, such as the G-quadruplex (G4) and i-motif (iM), are formed at guanine- and cytosine-rich sequences, respectively, i
doi.org
November 19, 2024 at 11:42 AM
Fingerprint-targeting enrichment enabled us to capture new candidate proteins that bind non- canonical i-motif DNA structure. Published in Nucleic Acids Research!
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
台湾大学化学科のManuel Maestre-Reyna博士のラボに一週間ほどお世話になるため、台湾に来ました。何とか次の論文を完成させたい！
October 23, 2024 at 8:11 AM
台湾大学化学科のManuel Maestre-Reyna博士のラボに一週間ほどお世話になるため、台湾に来ました。何とか次の論文を完成させたい！
東北大学際研•佐藤伸一准教授との共同研究がNucleic Acids Research誌に採択されました！JST創発をきっかけに同年代が知り合い意気投合し、お互いの得意分野を活かしたいい仕事が出来て大変満足です😊
October 21, 2024 at 2:12 PM
東北大学際研•佐藤伸一准教授との共同研究がNucleic Acids Research誌に採択されました！JST創発をきっかけに同年代が知り合い意気投合し、お互いの得意分野を活かしたいい仕事が出来て大変満足です😊