Jason Climer
@jrclimer.bsky.social
Assistant prof at UIUC interested in memory and how neural representations evolve over time.
https://climerlab.org
https://climerlab.org
Pinned
Jason Climer
@jrclimer.bsky.social
· Jul 23
Climer Lab postdoc search.docx | School of Molecular & Cellular Biology | Illinois
mcb.illinois.edu
If you’re interested in these questions, I’m recruiting a post-doc to join our team at the University of Illinois Urbana-Champaign! You may find the job posting here: mcb.illinois.edu/climerpostdoc
I’m excited to share my final co-first author paper from my postdoc in Dan Dombeck's lab!
We explored how behavior, senses, and neurons influence how much information in the brain changes over time.
www.nature.com/articles/s41...
#science #research #neuroscience #hippocampus #placecells
We explored how behavior, senses, and neurons influence how much information in the brain changes over time.
www.nature.com/articles/s41...
#science #research #neuroscience #hippocampus #placecells
Hippocampal representations drift in stable multisensory environments - Nature
Tracking of individual place cells in mouse CA1 shows that representational drift is not influenced by changes in environment or behaviour, and is lower for more excitable place cells.
www.nature.com
July 23, 2025 at 4:12 PM
I’m excited to share my final co-first author paper from my postdoc in Dan Dombeck's lab!
We explored how behavior, senses, and neurons influence how much information in the brain changes over time.
www.nature.com/articles/s41...
#science #research #neuroscience #hippocampus #placecells
We explored how behavior, senses, and neurons influence how much information in the brain changes over time.
www.nature.com/articles/s41...
#science #research #neuroscience #hippocampus #placecells
Reposted by Jason Climer
Very happy to see a Transmitter (@thetransmitter.bsky.social) piece on our recent work on estrous cycle modulation of hippocampal structure and function. Thanks to Sydney Wyatt (@sydneywyatt.bsky.social) for covering the work and its context:
www.thetransmitter.org/neuroendocri...
www.thetransmitter.org/neuroendocri...
Spatial learning circuitry fluctuates in step with estrous cycle in mice
Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.
www.thetransmitter.org
June 25, 2025 at 2:13 PM
Very happy to see a Transmitter (@thetransmitter.bsky.social) piece on our recent work on estrous cycle modulation of hippocampal structure and function. Thanks to Sydney Wyatt (@sydneywyatt.bsky.social) for covering the work and its context:
www.thetransmitter.org/neuroendocri...
www.thetransmitter.org/neuroendocri...
Reposted by Jason Climer
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415...
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
June 20, 2025 at 7:57 PM
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415...
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
What is the best measure of functional connectivity (FC)?
led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
Reposted by Jason Climer
🚨New paper alert! 🚨 Inactivation of the nucleus reuniens causes relapse of extinguished fear. Here we show this “circuit-induced relapse” depends on hippocampal fear memories and is mediated by hippocampal engrams. Congrats to the team!
Hippocampal ensembles regulate circuit-induced relapse of extinguished fear
Molecular Psychiatry - Hippocampal ensembles regulate circuit-induced relapse of extinguished fear
urldefense.com
May 24, 2025 at 6:35 PM
🚨New paper alert! 🚨 Inactivation of the nucleus reuniens causes relapse of extinguished fear. Here we show this “circuit-induced relapse” depends on hippocampal fear memories and is mediated by hippocampal engrams. Congrats to the team!
Reposted by Jason Climer
✨ Announcing a new glutamate indicator - iGluSnFR4! ✨
Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.
More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...
🧠📈
Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.
More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...
🧠📈
March 25, 2025 at 10:24 PM
✨ Announcing a new glutamate indicator - iGluSnFR4! ✨
Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.
More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...
🧠📈
Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.
More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...
🧠📈
Reposted by Jason Climer
This is great from @neuralreckoning.bsky.social
Great to see this Tim! Glad that eLife is standing up here. I was worried after HHMI cut their DEI programme.
Did you see my article btw?
www.thetransmitter.org/policy/scien...
Did you see my article btw?
www.thetransmitter.org/policy/scien...
March 25, 2025 at 5:13 PM
This is great from @neuralreckoning.bsky.social
Reposted by Jason Climer
All-optical electrophysiology reveals behavior-dependent dynamics of excitation and inhibition in the hippocampus https://www.biorxiv.org/content/10.1101/2025.03.20.644347v1
March 21, 2025 at 7:15 AM
All-optical electrophysiology reveals behavior-dependent dynamics of excitation and inhibition in the hippocampus https://www.biorxiv.org/content/10.1101/2025.03.20.644347v1
Reposted by Jason Climer
This list has doubled. Who haven’t I found?
go.bsky.app/LdtUYZS
I created a starter pack for the growing community of hippocampus physiologists that have joined the great migration. Also included the physiology-adjacent.
Tell me who I haven’t found yet
I created a starter pack for the growing community of hippocampus physiologists that have joined the great migration. Also included the physiology-adjacent.
Tell me who I haven’t found yet
November 18, 2024 at 5:44 PM
This list has doubled. Who haven’t I found?