Joyce Valadares
joycevaladares.bsky.social
Joyce Valadares
@joycevaladares.bsky.social
PhD researcher at the MRC MBU, University of Cambridge, studying cardiac metabolism during IR injury.
Excited to share that at the annual MRC MBU symposium I was awarded best poster prize for my PhD project on Succinate Metabolism in Cardiac Ischemia/ Reperfusion Injury! Thanks to my lab, collaborators, and my PI Mike Murphy. @mitoredox.bsky.social
October 20, 2025 at 1:58 PM
Reposted by Joyce Valadares
Great to see paper from Alva Casey out today in Nature Metabolism - from her PhD.
Well done Alva!

doi.org/10.1038/s422...
Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation - Nature Metabolism
Casey et al. explore the basic mechanisms of mitochondrial superoxide production and its impact on interleukin-1β production in LPS-treated macrophages.
doi.org
February 19, 2025 at 12:06 PM