Amit Joshi
@joshilaboratory.bsky.social
Assistant Professor at UTK. Interested in organelle formation and function. https://joshilaboratory.com
Pinned
Amit Joshi
@joshilaboratory.bsky.social
· May 23
Phosphatidic acid drives spatiotemporal distribution of Pex30 at ER-LD contact sites | Journal of Cell Biology | Rockefeller University Press
In this study, we show that Pex30 dysferlin domain binds PA through its two hydrophobic regions adjacent to beta sheets. We propose that, PA, a precursor f
rupress.org
Excited to present first publication from the Joshi lab, now in @jcb.org
Here, we show that phosphatidic acid regulates Pex30 distribution at ER subdomains for lipid droplet biogenesis by binding to dysferlin domain.
rupress.org/jcb/article/...
Here, we show that phosphatidic acid regulates Pex30 distribution at ER subdomains for lipid droplet biogenesis by binding to dysferlin domain.
rupress.org/jcb/article/...
Reposted by Amit Joshi
The p97 ATPase and its adaptor UBXD8 maintain #peroxisome pools by preventing #pexophagy, say Iris Montes, Malavika Raman @maliramanlab.bsky.social @tufts.edu and colleagues: rupress.org/jcb/article/...
@joshilaboratory.bsky.social
#Biochemistry #Organelles
@joshilaboratory.bsky.social
#Biochemistry #Organelles
August 5, 2025 at 2:33 PM
The p97 ATPase and its adaptor UBXD8 maintain #peroxisome pools by preventing #pexophagy, say Iris Montes, Malavika Raman @maliramanlab.bsky.social @tufts.edu and colleagues: rupress.org/jcb/article/...
@joshilaboratory.bsky.social
#Biochemistry #Organelles
@joshilaboratory.bsky.social
#Biochemistry #Organelles
Congratulations @maliramanlab.bsky.social!! Happy to have contributed to this study.
Montes et al. @maliramanlab.bsky.social @tufts.edu find the p97 ATPase and its adaptor UBXD8 maintain #peroxisome abundance by suppressing #pexophagy. p97-UBXD8 degrade ubiquitylated peroxisomal proteins to bypass recognition by #autophagy receptors. rupress.org/jcb/article/...
#Biochemistry
#Biochemistry
July 30, 2025 at 7:02 PM
Congratulations @maliramanlab.bsky.social!! Happy to have contributed to this study.
Reposted by Amit Joshi
Huge thanks to @gthibault.bsky.social and Julie Hollien for organizing a warm, welcoming FASEB ER meeting filled with incredible science! Excited that I will carry the torch as a co-organizer for the 2027 meeting….can’t wait! @faseborg.bsky.social
June 12, 2025 at 6:42 PM
Huge thanks to @gthibault.bsky.social and Julie Hollien for organizing a warm, welcoming FASEB ER meeting filled with incredible science! Excited that I will carry the torch as a co-organizer for the 2027 meeting….can’t wait! @faseborg.bsky.social
Reposted by Amit Joshi
Phosphatidic acid drives spatiotemporal distribution of Pex30 at ER-LD contact sites, say Morgan House, Amit S. Joshi @joshilaboratory.bsky.social and colleagues @utknoxville.bsky.social: rupress.org/jcb/article/...
#Organelles #Biochemistry #ER_literature #LipidDroplets #lipids
#Organelles #Biochemistry #ER_literature #LipidDroplets #lipids
May 30, 2025 at 7:03 PM
Phosphatidic acid drives spatiotemporal distribution of Pex30 at ER-LD contact sites, say Morgan House, Amit S. Joshi @joshilaboratory.bsky.social and colleagues @utknoxville.bsky.social: rupress.org/jcb/article/...
#Organelles #Biochemistry #ER_literature #LipidDroplets #lipids
#Organelles #Biochemistry #ER_literature #LipidDroplets #lipids
Excited to present first publication from the Joshi lab, now in @jcb.org
Here, we show that phosphatidic acid regulates Pex30 distribution at ER subdomains for lipid droplet biogenesis by binding to dysferlin domain.
rupress.org/jcb/article/...
Here, we show that phosphatidic acid regulates Pex30 distribution at ER subdomains for lipid droplet biogenesis by binding to dysferlin domain.
rupress.org/jcb/article/...
Phosphatidic acid drives spatiotemporal distribution of Pex30 at ER-LD contact sites | Journal of Cell Biology | Rockefeller University Press
In this study, we show that Pex30 dysferlin domain binds PA through its two hydrophobic regions adjacent to beta sheets. We propose that, PA, a precursor f
rupress.org
May 23, 2025 at 2:41 PM
Excited to present first publication from the Joshi lab, now in @jcb.org
Here, we show that phosphatidic acid regulates Pex30 distribution at ER subdomains for lipid droplet biogenesis by binding to dysferlin domain.
rupress.org/jcb/article/...
Here, we show that phosphatidic acid regulates Pex30 distribution at ER subdomains for lipid droplet biogenesis by binding to dysferlin domain.
rupress.org/jcb/article/...
Had a great time co-chairing the subgroup session with Laura Lackner @ASCB. The session was well attended, had fantastic talks and great discussion. Thank you to all the speakers!!
December 17, 2024 at 1:52 PM
Had a great time co-chairing the subgroup session with Laura Lackner @ASCB. The session was well attended, had fantastic talks and great discussion. Thank you to all the speakers!!
Reposted by Amit Joshi
Always wonderful to connect with so many friends at the ASCB | EMBO Cell Bio meeting! So much inspiring science! Thank you for organizing this dinner Sarah!! 🤩😊@cohenlaboratory.bsky.social #CellBio2024
December 16, 2024 at 5:54 AM
Always wonderful to connect with so many friends at the ASCB | EMBO Cell Bio meeting! So much inspiring science! Thank you for organizing this dinner Sarah!! 🤩😊@cohenlaboratory.bsky.social #CellBio2024
Reposted by Amit Joshi
If you are at #cellbio2024, please consider coming to the Membrane Contact Sites session tomorrow (12/16) at 5pm in room 29C! Many great talks planned! I will be presenting “Keep Calmin and Carry On: Tethering the ER to F-actin Enables Cell Migration” at 6. Hope to see you there!
December 16, 2024 at 12:24 AM
If you are at #cellbio2024, please consider coming to the Membrane Contact Sites session tomorrow (12/16) at 5pm in room 29C! Many great talks planned! I will be presenting “Keep Calmin and Carry On: Tethering the ER to F-actin Enables Cell Migration” at 6. Hope to see you there!
Reposted by Amit Joshi
🌟 Registration is now OPEN for the #FASEB Endoplasmic Reticulum Conference 2025 #ERSRC! 🎉 Join us June 8-12, 2025, in Melbourne 🏖️, FL, for cutting-edge science and networking.
Check out the program and register here 👇
events.faseb.org/event/endoplasmic-reticulum-function-disease
Check out the program and register here 👇
events.faseb.org/event/endoplasmic-reticulum-function-disease
Endoplasmic Reticulum
events.faseb.org
December 11, 2024 at 12:23 AM
🌟 Registration is now OPEN for the #FASEB Endoplasmic Reticulum Conference 2025 #ERSRC! 🎉 Join us June 8-12, 2025, in Melbourne 🏖️, FL, for cutting-edge science and networking.
Check out the program and register here 👇
events.faseb.org/event/endoplasmic-reticulum-function-disease
Check out the program and register here 👇
events.faseb.org/event/endoplasmic-reticulum-function-disease
Excited to co-chair a session on Cell Biology of Organelles with Laura Lackner @ascbiology.bsky.social #CellBio2024 on Monday, 12/16 at 5pm. We have a great line up of speakers.. check it out! 👇
December 9, 2024 at 11:17 PM
Excited to co-chair a session on Cell Biology of Organelles with Laura Lackner @ascbiology.bsky.social #CellBio2024 on Monday, 12/16 at 5pm. We have a great line up of speakers.. check it out! 👇