Josefa Macuada
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jmacuada.bsky.social
Josefa Macuada
@jmacuada.bsky.social
PhD student at the Mitochondriac VEisner Lab 🇨🇱. ♥️ live-cell imaging 🔬, reading, and merken (she/ella)
Reposted by Josefa Macuada
I'm so happy to share our work discussing nucleoid trafficking inside the mitochondrion and mitochondrial network, led by the amazing @jmacuada.bsky.social
Available in @cp-trendscellbio.bsky.social

www.cell.com/trends/cell-...

#mito #mitochondria
How are mitochondrial nucleoids trafficked?
Mitochondria harbor their own DNA (mtDNA), which codifies essential proteins of the oxidative phosphorylation (OXPHOS) system and locally feeds them to their surrounding inner mitochondrial membrane (...
www.cell.com
February 21, 2025 at 1:31 PM
Are you curious about how motile our mitochondrial genomes are 🧬? Live-cell nucleoid data inspired us to discuss exciting ideas from the field with amazing @isimolinar.bsky.social and Verónica Eisner in our new opinion at TCB 🤩! Here is a free-access link authors.elsevier.com/c/1keJq3QxxS....
February 21, 2025 at 3:54 PM
Reposted by Josefa Macuada
I’m ultra excited about our preprints on mitochondrial pearling. In two concurrent collaborative studies with @wallaceucsf.bsky.social, we investigated its consequences on mtDNA nucleoids (led by @jclandoni.bsky.social) & its biophysical causes (led by @gavsturm.bsky.social). Funders HFSP, ERC, SNSF
December 23, 2024 at 4:11 PM
Reposted by Josefa Macuada
Stoked to share TWO preprints on mitochondrial pearling! 🎉
We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and
@gavsturm.bsky.social
et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪
December 23, 2024 at 4:37 PM