José Luis Sardina
@jlsardinalab.bsky.social
Group Leader at Josep Carreras Leukaemia Institute | Epigenetics, Leukemia, Stem Cell Biology, Gene regulation |
Website: https://www.carrerasresearch.org/en/research/epigenetic-control-of-haematopoiesis
Website: https://www.carrerasresearch.org/en/research/epigenetic-control-of-haematopoiesis
Reposted by José Luis Sardina
#CABDseminars
"Rewriting Cell Identity Through TET2 Chromatin Profiling and DNA Methylation Editing" by José Luis Sardina @jlsardinalab.bsky.social, @carrerasijc.bsky.social
🗓️ November 7th
⏰ 12 pm
📍sala Grado, edificio 25 (biblioteca UPO) ‼️
Hosted by @obog.bsky.social
"Rewriting Cell Identity Through TET2 Chromatin Profiling and DNA Methylation Editing" by José Luis Sardina @jlsardinalab.bsky.social, @carrerasijc.bsky.social
🗓️ November 7th
⏰ 12 pm
📍sala Grado, edificio 25 (biblioteca UPO) ‼️
Hosted by @obog.bsky.social
November 3, 2025 at 2:01 PM
#CABDseminars
"Rewriting Cell Identity Through TET2 Chromatin Profiling and DNA Methylation Editing" by José Luis Sardina @jlsardinalab.bsky.social, @carrerasijc.bsky.social
🗓️ November 7th
⏰ 12 pm
📍sala Grado, edificio 25 (biblioteca UPO) ‼️
Hosted by @obog.bsky.social
"Rewriting Cell Identity Through TET2 Chromatin Profiling and DNA Methylation Editing" by José Luis Sardina @jlsardinalab.bsky.social, @carrerasijc.bsky.social
🗓️ November 7th
⏰ 12 pm
📍sala Grado, edificio 25 (biblioteca UPO) ‼️
Hosted by @obog.bsky.social
Reposted by José Luis Sardina
New paper alert – now in @ScienceAdvances
Congrats to IMMERGE PI José Luís Sardina and team!🎉
This study shows how targeted DNA methylation editing at a key immune gene can reshape cell fate and immune responses.
📷 Read more: pubmed.ncbi.nlm.nih.gov/40668918/
#IMMERGE #MSCA #CRISPR #epigenetics
Congrats to IMMERGE PI José Luís Sardina and team!🎉
This study shows how targeted DNA methylation editing at a key immune gene can reshape cell fate and immune responses.
📷 Read more: pubmed.ncbi.nlm.nih.gov/40668918/
#IMMERGE #MSCA #CRISPR #epigenetics
July 22, 2025 at 7:50 AM
New paper alert – now in @ScienceAdvances
Congrats to IMMERGE PI José Luís Sardina and team!🎉
This study shows how targeted DNA methylation editing at a key immune gene can reshape cell fate and immune responses.
📷 Read more: pubmed.ncbi.nlm.nih.gov/40668918/
#IMMERGE #MSCA #CRISPR #epigenetics
Congrats to IMMERGE PI José Luís Sardina and team!🎉
This study shows how targeted DNA methylation editing at a key immune gene can reshape cell fate and immune responses.
📷 Read more: pubmed.ncbi.nlm.nih.gov/40668918/
#IMMERGE #MSCA #CRISPR #epigenetics
Reposted by José Luis Sardina
Congratulations, Dr Obiols! 👩🔬
Mireia Obiols, researcher at the @jlsardinalab.bsky.social, has successfully defended her #PhD thesis today at the IJC Auditorium.
Proud of your dedication and hard work 💪
Mireia Obiols, researcher at the @jlsardinalab.bsky.social, has successfully defended her #PhD thesis today at the IJC Auditorium.
Proud of your dedication and hard work 💪
July 18, 2025 at 12:29 PM
Congratulations, Dr Obiols! 👩🔬
Mireia Obiols, researcher at the @jlsardinalab.bsky.social, has successfully defended her #PhD thesis today at the IJC Auditorium.
Proud of your dedication and hard work 💪
Mireia Obiols, researcher at the @jlsardinalab.bsky.social, has successfully defended her #PhD thesis today at the IJC Auditorium.
Proud of your dedication and hard work 💪
Reposted by José Luis Sardina
🚀The IMMERGE consortium met in Heidelberg for our 2nd training event & Midterm Review!
DCs joined sessions on:
🔬Epigenetic & Transcriptional Regulation
🧠Leadership & Management
Huge thanks to all involved—and to @embl.org for hosting us!
🌍Next stop: Milan!
👉 immergeproject.eu
#IMMERGE #MSCA
DCs joined sessions on:
🔬Epigenetic & Transcriptional Regulation
🧠Leadership & Management
Huge thanks to all involved—and to @embl.org for hosting us!
🌍Next stop: Milan!
👉 immergeproject.eu
#IMMERGE #MSCA
June 5, 2025 at 9:32 AM
🚀The IMMERGE consortium met in Heidelberg for our 2nd training event & Midterm Review!
DCs joined sessions on:
🔬Epigenetic & Transcriptional Regulation
🧠Leadership & Management
Huge thanks to all involved—and to @embl.org for hosting us!
🌍Next stop: Milan!
👉 immergeproject.eu
#IMMERGE #MSCA
DCs joined sessions on:
🔬Epigenetic & Transcriptional Regulation
🧠Leadership & Management
Huge thanks to all involved—and to @embl.org for hosting us!
🌍Next stop: Milan!
👉 immergeproject.eu
#IMMERGE #MSCA
🔬 Passionate about experimental hematology?
Apply now for the final @carrerasleaders.bsky.social Call and join our team to work at the intersection of epigenetics, chromatin biology, and blood cancer.
#Hematology #Epigenetics #postdoc
Learn more (shorturl.at/5x5sw) & Apply 👇
Apply now for the final @carrerasleaders.bsky.social Call and join our team to work at the intersection of epigenetics, chromatin biology, and blood cancer.
#Hematology #Epigenetics #postdoc
Learn more (shorturl.at/5x5sw) & Apply 👇
May 22, 2025 at 7:02 AM
🔬 Passionate about experimental hematology?
Apply now for the final @carrerasleaders.bsky.social Call and join our team to work at the intersection of epigenetics, chromatin biology, and blood cancer.
#Hematology #Epigenetics #postdoc
Learn more (shorturl.at/5x5sw) & Apply 👇
Apply now for the final @carrerasleaders.bsky.social Call and join our team to work at the intersection of epigenetics, chromatin biology, and blood cancer.
#Hematology #Epigenetics #postdoc
Learn more (shorturl.at/5x5sw) & Apply 👇
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Renata Chalupska & Dr. Saka from @embl.org 🧬
Renata investigates how immune monogenic syndromes impact blood cell development.
That’s a wrap on our IMMERGE series—13 brilliant researchers shaping immunology’s future! 🌍👏
#IMMERGE #MSCA #IEI
This week: Renata Chalupska & Dr. Saka from @embl.org 🧬
Renata investigates how immune monogenic syndromes impact blood cell development.
That’s a wrap on our IMMERGE series—13 brilliant researchers shaping immunology’s future! 🌍👏
#IMMERGE #MSCA #IEI
May 14, 2025 at 1:57 PM
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE!🔬
This week: Martí Leira & Dr. Vento-Tormo from @sangerinstitute.bsky.social!🧬
Martí explores novel regulators of Tregopathies to better understand immune dysregulation and its roots.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI
This week: Martí Leira & Dr. Vento-Tormo from @sangerinstitute.bsky.social!🧬
Martí explores novel regulators of Tregopathies to better understand immune dysregulation and its roots.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI
May 7, 2025 at 7:16 AM
🔬 Meet the Researchers Behind IMMERGE!🔬
This week: Martí Leira & Dr. Vento-Tormo from @sangerinstitute.bsky.social!🧬
Martí explores novel regulators of Tregopathies to better understand immune dysregulation and its roots.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI
This week: Martí Leira & Dr. Vento-Tormo from @sangerinstitute.bsky.social!🧬
Martí explores novel regulators of Tregopathies to better understand immune dysregulation and its roots.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Eric O'Shee & Dr. Geiger from IRB! 🧪✨
Eric studies how mutations linked to Treg dysfunction impair immune suppression, disrupt immune tolerance, and contributing to autoimmunity.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #Tregs
This week: Eric O'Shee & Dr. Geiger from IRB! 🧪✨
Eric studies how mutations linked to Treg dysfunction impair immune suppression, disrupt immune tolerance, and contributing to autoimmunity.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #Tregs
April 29, 2025 at 9:05 AM
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Franka Witthauer & Dr. Casini from Alia Therapeutics! ✨
Franka works on correcting mutations linked to primary immunodeficiencies using innovative, engineered CRISPR tools.👩🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #CRISPR
This week: Franka Witthauer & Dr. Casini from Alia Therapeutics! ✨
Franka works on correcting mutations linked to primary immunodeficiencies using innovative, engineered CRISPR tools.👩🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #CRISPR
April 23, 2025 at 1:14 PM
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Tharaa Mohammad & Dr. Rodriguez from qGenomics! 🧬
Tharaa studies how JAK/STAT and NF-κB signaling contribute to immune-related preeclampsia, uncovering maternal-fetal immune dynamics.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI
This week: Tharaa Mohammad & Dr. Rodriguez from qGenomics! 🧬
Tharaa studies how JAK/STAT and NF-κB signaling contribute to immune-related preeclampsia, uncovering maternal-fetal immune dynamics.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI
April 15, 2025 at 7:59 AM
Reposted by José Luis Sardina
Check out Epigenetic Control of Hematopoiesis lab led by Dr.
@jlsardinalab.bsky.social.
Eager to contribute to impactful research at the intersection of epigenetics, chromatin biology, and hematology? They’d love to hear from you!
Get in touch by June 1!
More: carrerasleaders.eu
#MSCA #postdoc
@jlsardinalab.bsky.social.
Eager to contribute to impactful research at the intersection of epigenetics, chromatin biology, and hematology? They’d love to hear from you!
Get in touch by June 1!
More: carrerasleaders.eu
#MSCA #postdoc
May 14, 2025 at 8:40 AM
Check out Epigenetic Control of Hematopoiesis lab led by Dr.
@jlsardinalab.bsky.social.
Eager to contribute to impactful research at the intersection of epigenetics, chromatin biology, and hematology? They’d love to hear from you!
Get in touch by June 1!
More: carrerasleaders.eu
#MSCA #postdoc
@jlsardinalab.bsky.social.
Eager to contribute to impactful research at the intersection of epigenetics, chromatin biology, and hematology? They’d love to hear from you!
Get in touch by June 1!
More: carrerasleaders.eu
#MSCA #postdoc
Reposted by José Luis Sardina
📢Looking for a #postdoc in blood cancers?
The CarrerasLeaders Call 4 is OPEN for exceptional applicants at @carrerasijc.bsky.social.
📅 Apply by June 1, 2025
✨World-class researchers supervision
✨International secondments
✨Top-tier research infrastructures
More details at carrerasleaders.eu
The CarrerasLeaders Call 4 is OPEN for exceptional applicants at @carrerasijc.bsky.social.
📅 Apply by June 1, 2025
✨World-class researchers supervision
✨International secondments
✨Top-tier research infrastructures
More details at carrerasleaders.eu
April 15, 2025 at 9:35 AM
📢Looking for a #postdoc in blood cancers?
The CarrerasLeaders Call 4 is OPEN for exceptional applicants at @carrerasijc.bsky.social.
📅 Apply by June 1, 2025
✨World-class researchers supervision
✨International secondments
✨Top-tier research infrastructures
More details at carrerasleaders.eu
The CarrerasLeaders Call 4 is OPEN for exceptional applicants at @carrerasijc.bsky.social.
📅 Apply by June 1, 2025
✨World-class researchers supervision
✨International secondments
✨Top-tier research infrastructures
More details at carrerasleaders.eu
Reposted by José Luis Sardina
Extremely happy to share that the first paper from our lab is now published! Driven by the very talented PhD student Maria Cadefau, we studied how CEBPA mutations shape transcriptional programs in AML. A thread 🧵👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mutant CEBPA promotes tolerance to inflammatory stress through deficient AP-1 activation - Nature Communications
CEBPA is frequently mutated in acute myeloid leukemia (AML), but the transcriptional impact of the AML-associated isoform remains unclear. Here, the authors show that CEBPA-mutant cells have reduced i...
www.nature.com
April 14, 2025 at 1:33 PM
Extremely happy to share that the first paper from our lab is now published! Driven by the very talented PhD student Maria Cadefau, we studied how CEBPA mutations shape transcriptional programs in AML. A thread 🧵👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Florence Melbert, @eballestar.bsky.social & @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Florence is studying how IKAROS mutations contribute to IEI.👩🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #IKAROS
This week: Florence Melbert, @eballestar.bsky.social & @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Florence is studying how IKAROS mutations contribute to IEI.👩🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #IKAROS
April 8, 2025 at 7:06 AM
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Florence Melbert, @eballestar.bsky.social & @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Florence is studying how IKAROS mutations contribute to IEI.👩🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #IKAROS
This week: Florence Melbert, @eballestar.bsky.social & @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Florence is studying how IKAROS mutations contribute to IEI.👩🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #IKAROS
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Andrea Carpinteiro & Dr. Di Micco from OSR! 🧬
Andrea explores how dysfunctional telomeres impact stem cells & immunity, revealing links between aging and immune regulation.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Telomeres
This week: Andrea Carpinteiro & Dr. Di Micco from OSR! 🧬
Andrea explores how dysfunctional telomeres impact stem cells & immunity, revealing links between aging and immune regulation.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Telomeres
March 25, 2025 at 8:11 AM
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Andrea Carpinteiro & Dr. Di Micco from OSR! 🧬
Andrea explores how dysfunctional telomeres impact stem cells & immunity, revealing links between aging and immune regulation.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Telomeres
This week: Andrea Carpinteiro & Dr. Di Micco from OSR! 🧬
Andrea explores how dysfunctional telomeres impact stem cells & immunity, revealing links between aging and immune regulation.
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Telomeres
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE!🔬
This week: Laura Artal & Dr. Klaus Warnatz from @uni-freiburg.de! Laura will focus on IKBKB deficiency, aiming to uncover its impact on patients with immunodeficiencies 🧬✨
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Immunology #IKBKB
This week: Laura Artal & Dr. Klaus Warnatz from @uni-freiburg.de! Laura will focus on IKBKB deficiency, aiming to uncover its impact on patients with immunodeficiencies 🧬✨
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Immunology #IKBKB
March 18, 2025 at 10:25 AM
🔬 Meet the Researchers Behind IMMERGE!🔬
This week: Laura Artal & Dr. Klaus Warnatz from @uni-freiburg.de! Laura will focus on IKBKB deficiency, aiming to uncover its impact on patients with immunodeficiencies 🧬✨
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Immunology #IKBKB
This week: Laura Artal & Dr. Klaus Warnatz from @uni-freiburg.de! Laura will focus on IKBKB deficiency, aiming to uncover its impact on patients with immunodeficiencies 🧬✨
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Immunology #IKBKB
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: @angelopilotti.bsky.social & Dr. Pierre from @cnrs.fr!
Angelo will study the functional impact of EIF2AK mutants in dendritic cells & interferonopathies🧬👨🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #DCs #Interferonopathies
This week: @angelopilotti.bsky.social & Dr. Pierre from @cnrs.fr!
Angelo will study the functional impact of EIF2AK mutants in dendritic cells & interferonopathies🧬👨🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #DCs #Interferonopathies
March 4, 2025 at 7:58 AM
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: @angelopilotti.bsky.social & Dr. Pierre from @cnrs.fr!
Angelo will study the functional impact of EIF2AK mutants in dendritic cells & interferonopathies🧬👨🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #DCs #Interferonopathies
This week: @angelopilotti.bsky.social & Dr. Pierre from @cnrs.fr!
Angelo will study the functional impact of EIF2AK mutants in dendritic cells & interferonopathies🧬👨🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #DCs #Interferonopathies
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Giulia Bressan & Dr. Bodo Grimbacher from @uni-freiburg.de!
Giulia will dive into STAT3 regulation & signaling to better understand immune function👩🔬🌟
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Immunology #STAT3
This week: Giulia Bressan & Dr. Bodo Grimbacher from @uni-freiburg.de!
Giulia will dive into STAT3 regulation & signaling to better understand immune function👩🔬🌟
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Immunology #STAT3
March 11, 2025 at 2:06 PM
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Giulia Bressan & Dr. Bodo Grimbacher from @uni-freiburg.de!
Giulia will dive into STAT3 regulation & signaling to better understand immune function👩🔬🌟
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Immunology #STAT3
This week: Giulia Bressan & Dr. Bodo Grimbacher from @uni-freiburg.de!
Giulia will dive into STAT3 regulation & signaling to better understand immune function👩🔬🌟
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #Immunology #STAT3
Reposted by José Luis Sardina
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Emily Flaschner & Dr. @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Emily's research explores TET-mediated epigenetic control in NF-κB mutated patients👩🔬🌟
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #Epigenetics #NFkB #IEI
This week: Emily Flaschner & Dr. @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Emily's research explores TET-mediated epigenetic control in NF-κB mutated patients👩🔬🌟
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #Epigenetics #NFkB #IEI
February 25, 2025 at 8:04 AM
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: Emily Flaschner & Dr. @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Emily's research explores TET-mediated epigenetic control in NF-κB mutated patients👩🔬🌟
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #Epigenetics #NFkB #IEI
This week: Emily Flaschner & Dr. @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Emily's research explores TET-mediated epigenetic control in NF-κB mutated patients👩🔬🌟
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #Epigenetics #NFkB #IEI
Reposted by José Luis Sardina
Celebration Tuesday! 🥳
🎉 Congratulations to Gemma Varcárcel 👩🎓 (Dr. JL Sardina's lab) who has successfully defended her #thesis in how to use gene editing tools to influence immune cell differentiation and function, a promising approach against cancer 👏
🎉 Congratulations to Gemma Varcárcel 👩🎓 (Dr. JL Sardina's lab) who has successfully defended her #thesis in how to use gene editing tools to influence immune cell differentiation and function, a promising approach against cancer 👏
January 21, 2025 at 4:29 PM
Celebration Tuesday! 🥳
🎉 Congratulations to Gemma Varcárcel 👩🎓 (Dr. JL Sardina's lab) who has successfully defended her #thesis in how to use gene editing tools to influence immune cell differentiation and function, a promising approach against cancer 👏
🎉 Congratulations to Gemma Varcárcel 👩🎓 (Dr. JL Sardina's lab) who has successfully defended her #thesis in how to use gene editing tools to influence immune cell differentiation and function, a promising approach against cancer 👏