Jochem Smit
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jhsmit.bsky.social
Jochem Smit
@jhsmit.bsky.social
Biophysics; protein dynamics/folding using smFRET and HDX-MS.

https://jhsmit.org/
Just updated my hikemap with our Ardennes hikes!🗺️🥾
One of the perks of living in Belgium: epic trails basically in your backyard 🇧🇪🌳

There are a couple of cool two-day hikes here as well which were (rather painful😅) training sessions for our Norway adventure 🇳🇴🏔️

jhsmit.org/hikes/hikema...

#hiking
July 16, 2025 at 8:51 AM
Such a pleasure to define HDX-MS states directly in VS code!

#solara #hdxms-datasets
May 20, 2025 at 1:42 PM
Having some fun with 3DPGA & kingdon (GA library for python) in ipymolstar!

Geometric Algebra feels like magic 🪄; I don't understand it but surely its very powerful 💪

Live example on pycafe: py.cafe/jhsmit/ipymo...
April 29, 2025 at 1:08 PM
New release for #ipymolstar: I've added a widget for the amazing and very powerful MolViewSpec. This allows you to control the camera📷from python🐍, as well as all other molviewspec features 🎉

ipymolstar repo: github.com/jhsmit/ipymo...
Molviewspec: molstar.org/mol-view-spec/
April 10, 2025 at 10:24 AM
Reposted by Jochem Smit
I was invited, for July, to a scienctific meeting in Telluride (Colorado). I was told it is a wonderful place for a conference, and I was very much looking forward to an exciting meeting in a fantastic environment. I have just canceled my participation, despite having booked already everything.
French scientist denied US entry after phone messages critical of Trump found
France’s research minister said the scientist was traveling to Houston for a conference when his phone was searched
www.theguardian.com
March 23, 2025 at 10:44 AM
Reposted by Jochem Smit
Hi folks, I would like to know which EU universities are willing or planning to organise #standupforscience activities in solidarity with US scientists Please contact me if you are. Thanks for reposting!
What if we would organise a solidarity action at our universities all across the world? Who would be in? I am tossing this idea on the next council meeting for international affairs at KU Leuven, Belgium. Please spread #standupforscience
Welcome to the Bluesky account for Stand Up for Science 2025!

Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!

#scienceforall #sciencenotsilence
February 19, 2025 at 7:34 AM
Reposted by Jochem Smit
In today’s Vatnik Soup, I’ll introduce how the Elon Musk’s Election Interference Machine™ (EIM) works. Since Musk and his broligarch allies won the presidency for Trump, they’ve now harnessed the machine to interfere in European elections, including the ones in Germany and Romania.

1/23
February 18, 2025 at 1:01 PM
I have some exciting news to share!!

A cute little boy arrived in our lives early december
Mom & dad are very tired but happy 😃

birth card illustration by Tintenbaum
tintenbaum.com
January 6, 2025 at 2:56 PM
Here's a neat way to share you protein-annotated data 🚀🧪

Upload your .csv with residue/value data, select data column, colormap and norm to interactively color your protein model.

Then, add title/description and click the button to open a shareable view with url-encoded data and settings.
December 6, 2024 at 3:17 PM
#ipymolstar v0.0.9: Added click interactions

try it on pycafé: py.cafe/jhsmit/ipymo...
November 29, 2024 at 4:58 PM
Two-way tertiary/primary structure hover and highlight with #ipymolstar and #altair

Try it on pycafe: py.cafe/jhsmit/ipymo...
November 7, 2024 at 3:21 PM
Reposted by Jochem Smit
"In the Netherlands — where the Party for Freedom (PVV), led by the anti-Islam firebrand Geert Wilders, entered a coalition government in July — researchers are bracing for €1 billion (US$1.1 billion) in cuts to the budget, the worst in decades."
Far-right governments seek to cut billions of euros from research in Europe
Anti-immigration parties are pushing policies that are hostile or indifferent towards science.
www.nature.com
October 29, 2024 at 10:09 AM
By popular demand: How much monomer/dimer/tetramer are formed at steady-state given the two kds and the total concentration of protomer? 🧐

py.cafe/jhsmit/tetra...
PyCafe - Solara - Tetramerization Kinetics Analysis
PyCafe: get your daily fix of Python!
py.cafe
June 13, 2024 at 3:18 PM
I've created this #solara app where you can drag & drop your #alphafold3 .zip file and switch between chain color or plddt colors. Includes 'spin' and theme toggle for maximal viewing pleasure. The screenshot below shows the elusive SecA2/SecB4 complex.
huggingface.co/spaces/Jhsmi...
May 13, 2024 at 10:53 AM
New in #ipymolstar version 0.0.4: directly load your local data files

`pip install "ipymolstar==0.0.4"`
github.com/Jhsmit/ipymo...
April 25, 2024 at 9:19 AM
Reposted by Jochem Smit
Dit is en blijft racisme. Iemand uit Afrika mag geen mening hebben over het Fries en komt gewoon geld graaien.

Ik vind het ontluisterend dat dit op tv is en blijft.
April 11, 2024 at 6:10 AM
I've created my first widget with #anywidget! Its called `ipymolstar` and allows visualization of proteins or molecules interactively from python.

check out the video below or try it live on ploomber:
youtu.be/Syra-DCtQkA
ipymolstar
demo of ipymolstar in a solara app ipymolstar source: https://github.com/Jhsmit/ipymolstar example app source and live demo: https://github.com/Jhsmit/ploomber-solara-ipymolstar
youtu.be
March 18, 2024 at 6:51 PM
Reposted by Jochem Smit
Interested in the mechanisms driving subcellular organization in bacteria? The Vecchiarelli lab has a postdoc position available!

docs.google.com/document/d/1...

Plz RT!
February 14, 2024 at 4:12 PM