Jenn Hammel
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jennhammel.bsky.social
Jenn Hammel
@jennhammel.bsky.social
Postdoc in the Gerecht Lab @ Duke
PhD in BME @ Virginia Tech
Lymphatics & tissue engineering
I'm delighted to share the latest pub from my PhD work! In this work, co-first authored by Monet Roberts and myself, we found that systemic taxane chemotherapy damaged the meningeal lymphatics using in vitro, ex vivo, and in vivo models ⬇️🧪

#scisky #academicsky

www.nature.com/articles/s42...
Demonstration of chemotherapeutic-mediated changes in meningeal lymphatics in vitro, ex vivo, and in vivo - Communications Biology
In vitro, ex vivo, and in vivo models reveal that taxane chemotherapy disrupts meningeal lymphatic barrier function and vessel structure, alongside changes in fluid flow and impaired cognition.
www.nature.com
October 22, 2025 at 8:47 PM
Happy to share a new pre-print from my graduate work at VT! We tested how the engineered lymphatic stroma models I developed could be used to study central nervous system leukemia ⬇️🧪 #scisky

www.biorxiv.org/content/10.1...
Engineered lymphatic stroma model applications in central nervous system leukemia
Central nervous system (CNS) involvement frequently occurs in acute lymphoblastic leukemia (ALL), but many questions remain about how leukemia cells access, persist in, and exploit the CNS. The CNS is...
www.biorxiv.org
September 10, 2025 at 2:50 PM
I'm very excited to share that I've been selected as a Duke University KURe Scholar! With this funding, I will study the long-term impacts of radiotherapy on the bladder using tissue engineering with the goal of understanding and treating radiation cystitis in cancer survivors #scisky
August 21, 2025 at 6:09 PM
Reposted by Jenn Hammel
Postdoc @jennhammel.bsky.social representing the lab today at the 2025 North Carolina Postdoc Symposium at the NC Biotechnology Center. We have an incredible community of scientists here in NC! #scisky #academicsky 🧪🔬
June 20, 2025 at 2:57 PM
Very excited to share a new publication from my PhD work on our engineered lymph node stroma model! We saw flow-mediated changes to T cell egress and stroma morphology and inflammation 🧪🔬 @pompanolab.bsky.social
pubs.aip.org/aip/apb/arti... #scisky #immunoengineering
Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change
The lymph node (LN) performs essential roles in immunosurveillance throughout the body. Developing in vitro models of this key tissue is of great importance to
pubs.aip.org
April 4, 2025 at 3:17 PM
Very excited to be starting my post doc at Duke with the Gerecht Lab! I'll be studying the dynamics of extracellular matrix and immune function #immunoengineering
#scisky We're welcoming new postdoc
@jennhammel.bsky.social to the lab 👩‍🔬 🧪

She received her PhD from Virginia Tech and is interested in exploring the impact of the ECM in innate and adaptive immunity, sex differences, and metabolism. She also loves fantasy/sci-fi books, museums, and hockey!
February 3, 2025 at 6:59 PM
Reposted by Jenn Hammel
My whole team is excited to share our preprint with you, on an #OrganOnChip model of T cell-B cell interactions in the human lymph node! This is a model of antibody production starting from naive T cells and B cells, in a 3D microenvironment. #immunoengineering

www.biorxiv.org/content/10.1...
January 15, 2025 at 11:00 PM
New pre-print! Check out our engineered lymph node stroma model. We showcase its applications in interstitial fluid flow and immune cell egress www.biorxiv.org/content/10.1...
Engineered human lymph node stroma model for examining interstitial fluid flow and T cell egress
The lymph node (LN) performs essential roles in immunosurveillance throughout the body. Developing in vitro models of this key tissue is of great importance to enhancing physiological relevance in imm...
www.biorxiv.org
December 10, 2024 at 8:37 PM