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JAMA Ophthalmology
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JAMA Ophthalmology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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This case report describes a large choroidal excavation and outer retinal atrophy in an otherwise healthy man aged 29 years who presented with bilateral gradually worsening vision since childhood. ja.ma/49Y0DET
November 17, 2025 at 2:00 PM
This case report documents vision outcomes in a 15-year-old boy following orbital cellulitis and subperiosteal abscess. ja.ma/3K5QY4B
November 16, 2025 at 2:00 PM
Between 2014 and 2024, the number of ophthalmology practice locations increased, leading to improved access and reduced average driving distances from isolated optometry offices to ophthalmologists. ja.ma/47Zdxjk
November 15, 2025 at 2:00 PM
Interview with Darren Shu Jeng Ting, PhD author of Performance of Foundation Models Vs Doctors in Textual and Multimodal Ophthalmological Questions.

Hosted by Neil Bressler, MD. ja.ma/47y9lbv
Foundation Models vs Physicians in Ophthalmological Questions
Interview with Darren Shu Jeng Ting, MBChB, PhD, author of Performance of Foundation Models vs Physicians in Textual and Multimodal Ophthalmological Questions. Hosted by Neil Bressler, MD.
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November 14, 2025 at 4:23 PM
Manual marking-assisted capsulorhexis achieves similar accuracy and stability as digital guidance in cataract surgery.

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November 14, 2025 at 4:23 PM
Claude 3.5 Sonnet and GPT-4o outperform previous models and trainees in answering textual ophthalmology questions, but multimodal capabilities remain insufficient for clinical application. ja.ma/3LXwueQ
November 13, 2025 at 4:30 PM
Nearly 7% of US residents live over two hours from neuro-ophthalmology care, with the greatest gaps in rural and socioeconomically disadvantaged areas. ja.ma/3JMLr2O
November 11, 2025 at 2:00 PM
A previously healthy 31-year-old woman presents with acute unilateral anterior uveitis with hypopyon and an iris lesion and systemic symptoms, including headache, fatigue, and fever. What would you do next? ja.ma/3LuhvZW
November 10, 2025 at 2:00 PM
Apraclonidine eye drops may cause severe CNS and respiratory depression in infants and young children. ja.ma/3XeZn8O
November 9, 2025 at 2:00 PM
Five-year outcomes after pediatric traumatic cataract surgery showed low rates of glaucoma but frequent need for additional surgery and continued risk of vision loss.

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November 8, 2025 at 2:00 PM
Rigid gas-permeable contact lenses yielded superior visual outcomes compared to glasses in children following primary congenital #glaucoma surgery. ja.ma/43RkpOn
November 7, 2025 at 2:00 PM
Distinctive HR-OCT features in pseudoxanthoma elasticum highlight Bruch membrane calcification and provide a potential early marker for progression and treatment response.

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November 6, 2025 at 5:00 PM
Multifocal geographic atrophy is associated with faster progression and visual decline; risk factors for new lesion formation overlap only partially with those for initial GA occurrence.

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November 6, 2025 at 4:30 PM
This case report describes the grading and effects of myopic traction maculopathy in eyes with high myopia. ja.ma/4nrYzs1
November 4, 2025 at 12:00 PM
This case report discusses a diagnosis of posterior lenticonus with intralenticular cracks found during a school vision screening in a girl aged 8 years referred for decreased visual acuity in the left eye. ja.ma/4owwGzG
November 2, 2025 at 12:00 PM
This case report discusses a diagnosis of medication-associated maculopathy in a 44-year-old woman receiving exemestane treatment after breast cancer resection. ja.ma/4hv2oeA
November 1, 2025 at 12:00 PM
Case report: Oral tofacitinib achieved rapid and sustained remission in cases of refractory thyroid eye disease, targeting proinflammatory cytokine pathways implicated in orbital fibroblast activation. ja.ma/4oxIAJI
October 31, 2025 at 1:00 PM
Interview with Noemi Lois, MD, PhD, author of Retinal Sensitivity and Retinal Perfusion in Diabetic Retinopathy. Hosted by Neil Bressler, MD. ja.ma/4ogBc5W
https://ja.ma/48UnLUj
Retinal Sensitivity and Retinal Perfusion in Diabetic Retinopathy
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October 30, 2025 at 4:00 PM
Retinal capillary nonperfusion produces greater sensitivity deficits in people with #diabetic retinopathy, but one-third of perfused areas also show reduced function. ja.ma/4qthvJz
October 30, 2025 at 3:30 PM
RCT: Low-level red-light therapy for #myopia control slows axial elongation and refractive change, with some participants showing temporary retinal changes on OCT which resolved without affecting vision. ja.ma/3Wm4Dam
October 29, 2025 at 11:00 AM
Smooth pursuit eye movement velocity in Division I American football players was not affected by repetitive head impacts during a single season. ja.ma/3JewPsN
October 28, 2025 at 12:00 PM
While the incidence of ocular complications was higher in myopic children compared to nonmyopic ones, atropine use for #myopia control was not associated with these risks. ja.ma/4nnK2NH
October 27, 2025 at 11:00 AM
Advanced multimodal imaging indicates that vision loss in AZOOR initiates at the level of phototransduction within photoreceptor outer segments. ja.ma/4quIYdW
October 26, 2025 at 1:00 PM
Metformin use is not significantly associated with the development or progression of age-related macular degeneration (AMD), suggesting similar risks of AMD and its progression between those prescribed metformin and those not. ja.ma/3LcoqXj
October 26, 2025 at 12:00 PM
#GLP-1RA use was associated with reduced risk of developing nonexudative AMD but was not associated with progression to exudative AMD among individuals with nonexudative AMD.

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October 25, 2025 at 1:00 PM