Steve Jacobsen
jacobsenucla.bsky.social
Steve Jacobsen
@jacobsenucla.bsky.social
UCLA Professor and HHMI Investigator interested in plant epigenetics and plant genome editing.
Our paper is just out www.nature.com/articles/s41... from the Jacobsen, Doudna, and Banfield labs on viral delivery of a tiny CRISPR system for transgene free germline editing in plants, tinyurl.com/3k223r3x. Looking for postdocs to join the team for the next phase of this work!
Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis - Nature Plants
Weiss et al. engineered the tobacco rattle virus to express the RNA-guided TnpB enzyme ISYmu1 and guide RNA for transgene-free germline editing in Arabidopsis thaliana.
www.nature.com
May 1, 2025 at 2:24 PM
Reposted by Steve Jacobsen
In a new paper, IGI's Jennifer Doudna @doudna-lab.bsky.social and Jill Banfield @banfieldlab.bsky.social collaborate with UCLA's @jacobsenucla.bsky.social to create a new, tiny #CRISPR tool for quicker, easier plant genome editing! Read more: ow.ly/6Szs50VGElf
April 24, 2025 at 3:59 PM
Reposted by Steve Jacobsen
Hi plant epigenetics fans!
I have updated the Plant Epigenetics Starter Pack to include additional researchers in the field:
@jacobsenucla.bsky.social @pecinka-grp.bsky.social @manavellalab.bsky.social
Please let me know if you wish to be added to the Starter Pack!
go.bsky.app/HyTwdc2
March 14, 2025 at 12:34 PM
Reposted by Steve Jacobsen
Back-to-back manuscripts from the Jacobsen and Law labs revealing TFs that direct RdDM! Genetics controlling epigenetics. Reminiscent of KRAB ZFs... shorturl.at/TE4PH shorturl.at/QEHDU
Transcription factors instruct DNA methylation patterns in plant reproductive tissues
DNA methylation is maintained by forming self-reinforcing connections with other repressive chromatin modifications, resulting in stably silenced genes and transposons. However, these mechanisms fail ...
shorturl.at
February 24, 2025 at 8:59 PM