Jackie Zorz
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jackiezorz.bsky.social
Jackie Zorz
@jackiezorz.bsky.social
Bioinformatician | Microbial ecologist | Type 2 fun

https://jkzorz.github.io/blog/
Reposted by Jackie Zorz
New paper out: An archaeal genetic code with all TAG codons as pyrrolysine: www.science.org/doi/10.1126/...
An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...
www.science.org
November 23, 2025 at 7:22 PM
Reposted by Jackie Zorz
Most plasmids described in E. coli are small compared to the megaplasmids we identified here! Check out the preprint if you want to learn about these mysterious large elements and their potential functions 🧬. I’m very grateful to have had the opportunity to work on this in @banfieldlab.bsky.social
Megaplasmids associate with Escherichia coli and other Enterobacteriaceae https://www.biorxiv.org/content/10.1101/2025.09.30.679422v1
October 1, 2025 at 5:10 AM
Reposted by Jackie Zorz
Today in @nature.com , we highlight how a cousin of CRISPR-Cas10, mCpol, establishes an evolutionary trap in anti-phage immune systems.

Check out @erinedoherty.bsky.social and my work from @doudna-lab.bsky.social lab here:
www.nature.com/articles/s41...
A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling - Nature
Panoptes, an anti-phage defence system against virus-mediated immune suppression, is revealed.
www.nature.com
October 1, 2025 at 5:57 PM
Reposted by Jackie Zorz
I'm very excited to share our manuscript for Cenote-Taker 3. We show that (1) CT3 quickly and accurately annotates previously uncatalogued virus genomes and (2) finds divergent virus genomes in contiguous assemblies. Virome benchmarks are SO hard, but I think we came up with clever and useful ones.
August 25, 2025 at 2:36 PM
Excited to see this out! Congrats @andrejakust.bsky.social and team! 🦠🧬🎉
🚨 Fresh from the press! We created and analyzed over 100 in vitro cyanobacterial consortia using well-characterized model cyanobacterial hosts to better understand how cyanobacteria recruit and interact with their microbiomes.

Check it out: doi.org/10.1093/isme...
July 11, 2025 at 3:13 PM
Reposted by Jackie Zorz
🥳🥳 Our work exploring the core microbiomes of stable cyanobacterial communities is now out in the @isme-microbes.bsky.social Journal!!! Excellent work by @andrejakust.bsky.social and company!

#microbiology #cyanobacteria #metagenomics
Out now from @diamondlab.bsky.social — stable microbiome communities using tractable cyanobacteria. An important development for folks working on cyanobacteria, microbial community formation and establishment in lab settings, and microbial community ecology! Read here: tinyurl.com/3cs2x6r7
July 10, 2025 at 9:16 PM
Reposted by Jackie Zorz
Many of you gave me so much encouragement when I posted here earlier about my 10 year long passion project to make a microbial map of the ocean. Pinch me because I can't believe I get to update you that today that research was published in the journal SCIENCE! @science.org
July 10, 2025 at 7:29 PM
Reposted by Jackie Zorz
We’re happy to share our preprint where applied phages to Microbiomes to test microbial interaction hypotheses - without losing the relevance of the community.

Bonus: using SNPs we studied how our targeted organism recovers from infection, and find how the community likely influences this process.
Phage-based microbiome manipulation elucidates interactions within community context https://www.biorxiv.org/content/10.1101/2025.06.20.660599v1
June 22, 2025 at 8:49 PM
Reposted by Jackie Zorz
We're looking for a postdoc in marine microbial environmental genomics to join us at the Baltic Sea Centre and SciLifeLab at Stockholm University. Share and get in touch with any questions, welcome to apply!
Come work with us! We are currently hiring a Postdoctoral Fellow in marine microbial environmental genomics, to focus on microorganisms that produce and consume greenhouse gases and volatile organic compounds (VOCs) in the coastal Baltic Sea. Apply before 22 June! su.varbi.com/en/what:job/...
Postdoctoral Fellow in Marine microbial environmental genomics
Stockholm University’s Baltic Sea Centre (BSC) conducts research on the Baltic Sea environment and supports research and education related to the Baltic Sea carried out at various departments within
su.varbi.com
May 22, 2025 at 8:37 AM
Reposted by Jackie Zorz
CoverM is published!

CoverM: Read alignment statistics for metagenomics academic.oup.com/bioinformati... #jcampubs
CoverM: Read alignment statistics for metagenomics
AbstractSummary. Genome-centric analysis of metagenomic samples is a powerful method for understanding the function of microbial communities. Calculating r
academic.oup.com
April 9, 2025 at 1:24 PM
Reposted by Jackie Zorz
Nice perspective in Science summing up recent advances on the importance of phosphate to the origin of life and featuring my lab's favorite field sites: Lakes Goodenough and Last Chance... (photo is Mono Lake though) www.science.org/content/arti...
Unusual ‘soda lakes’ may have kick-started life on Earth by concentrating key compounds
Phosphorus leached from volcanic rocks in warm waters could have triggered reactions needed to launch biochemistry
www.science.org
February 28, 2025 at 5:15 PM
Reposted by Jackie Zorz
Microbial reaction rate estimation using proteins and proteomes academic.oup.com/ismej/advanc... #jcampubs
February 3, 2025 at 2:45 PM