Iván Núñez Martín
@ivannm97.bsky.social
PhD student at @AguileraLab, @CABIMER. Interested in DNA replication and genome instability
Reposted by Iván Núñez Martín
🔬Revelan factores potencialmente claves en la resistencia al daño de las células cancerosas
👩🔬Un equipo del @cbm-csic-uam.bsky.social ha identificado factores que amenazan la supervivencia celular cuando falla la vigilancia, como ocurre en los tumores
➡️ http://tiny.cc/tves001
👩🔬Un equipo del @cbm-csic-uam.bsky.social ha identificado factores que amenazan la supervivencia celular cuando falla la vigilancia, como ocurre en los tumores
➡️ http://tiny.cc/tves001
September 11, 2025 at 8:03 AM
🔬Revelan factores potencialmente claves en la resistencia al daño de las células cancerosas
👩🔬Un equipo del @cbm-csic-uam.bsky.social ha identificado factores que amenazan la supervivencia celular cuando falla la vigilancia, como ocurre en los tumores
➡️ http://tiny.cc/tves001
👩🔬Un equipo del @cbm-csic-uam.bsky.social ha identificado factores que amenazan la supervivencia celular cuando falla la vigilancia, como ocurre en los tumores
➡️ http://tiny.cc/tves001
Excited to share my first PhD paper published in @narjournal.bsky.social! This project was led by amazing supervisor Belén Gómez González in @aguilerloop.bsky.social lab. Thanks to all colaborators of Blanco and Diffley teams. I hope you like it!
Now online here 👇🏼 academic.oup.com/nar/article/...
Now online here 👇🏼 academic.oup.com/nar/article/...
S-phase checkpoint protects from aberrant replication fork processing and degradation
Abstract. Replication stress, a hallmark of cancer cells, is detected by checkpoint mechanisms that trigger a range of cellular responses. Among these, the
academic.oup.com
July 31, 2025 at 4:25 PM
Excited to share my first PhD paper published in @narjournal.bsky.social! This project was led by amazing supervisor Belén Gómez González in @aguilerloop.bsky.social lab. Thanks to all colaborators of Blanco and Diffley teams. I hope you like it!
Now online here 👇🏼 academic.oup.com/nar/article/...
Now online here 👇🏼 academic.oup.com/nar/article/...
Reposted by Iván Núñez Martín
Our latest study from my postdoctoral work has just been published in Science Advances!
Grateful to my mentor and collaborators who made it possible! @buissonlab.bsky.social @ucirvine.bsky.social
🔗 www.science.org/doi/10.1126/...
Grateful to my mentor and collaborators who made it possible! @buissonlab.bsky.social @ucirvine.bsky.social
🔗 www.science.org/doi/10.1126/...
Mechanism of DNA replication fork breakage and PARP1 hyperactivation during replication catastrophe
Upon ATR inhibition, APOBEC3B targets unprotected single-stranded DNA at replication forks, leading to fork breakage.
www.science.org
April 16, 2025 at 7:13 PM
Our latest study from my postdoctoral work has just been published in Science Advances!
Grateful to my mentor and collaborators who made it possible! @buissonlab.bsky.social @ucirvine.bsky.social
🔗 www.science.org/doi/10.1126/...
Grateful to my mentor and collaborators who made it possible! @buissonlab.bsky.social @ucirvine.bsky.social
🔗 www.science.org/doi/10.1126/...
Reposted by Iván Núñez Martín
Glad to see our PACT preprint published in @naturecomms.bsky.social!
"Cooperative role of PACT and ADAR1 in preventing aberrant PKR activation by self-derived double-stranded RNA"
Another step forward in understanding innate immunity. @buissonlab.bsky.social
🔗 www.nature.com/articles/s41...
"Cooperative role of PACT and ADAR1 in preventing aberrant PKR activation by self-derived double-stranded RNA"
Another step forward in understanding innate immunity. @buissonlab.bsky.social
🔗 www.nature.com/articles/s41...
April 7, 2025 at 5:21 PM
Glad to see our PACT preprint published in @naturecomms.bsky.social!
"Cooperative role of PACT and ADAR1 in preventing aberrant PKR activation by self-derived double-stranded RNA"
Another step forward in understanding innate immunity. @buissonlab.bsky.social
🔗 www.nature.com/articles/s41...
"Cooperative role of PACT and ADAR1 in preventing aberrant PKR activation by self-derived double-stranded RNA"
Another step forward in understanding innate immunity. @buissonlab.bsky.social
🔗 www.nature.com/articles/s41...