Hypothesis Fund
@hypothesisfund.bsky.social
Nimble funding for nimble minds.
www.hypothesisfund.org
www.hypothesisfund.org
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📣Exciting day at the @HypothesisFund! We’re thrilled to recognize two new brilliant scientist Scouts: Roseanna Zia and Dipti Nayak! 1/
Reposted by Hypothesis Fund
It was lovely speaking to @harmitmalik.bsky.social for @dmmjournal.bsky.social Infectious Disease Special Issue. We chatted about his work on host-viral evolution, the importance of blue-skies research and his approach to creating a supportive lab environment
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
For our #InfectiousDisease Special Issue we interviewed the marvelous @harmitmalik.bsky.social ! We discussed the #viral arms race, how to support mentees and the beauty of basic science 🔬
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
The viral arms race: an interview with Harmit Malik
Harmit Malik. Photo credit: Fred Hutchinson Cancer Research Center.Harmit Malik is Professor and Associate Director of the Basic Sciences Division at the Fred Hutchinson Cancer Center in Seattle, WA,…
journals.biologists.com
November 10, 2025 at 4:13 PM
It was lovely speaking to @harmitmalik.bsky.social for @dmmjournal.bsky.social Infectious Disease Special Issue. We chatted about his work on host-viral evolution, the importance of blue-skies research and his approach to creating a supportive lab environment
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
Reposted by Hypothesis Fund
The ocean’s got rhythm — and so do its viruses.
With the Bermuda Atlantic Time-Series (BATS), we dove deep — every 4 to 12 hours — to see how viral populations swing through day and night.
With the Bermuda Atlantic Time-Series (BATS), we dove deep — every 4 to 12 hours — to see how viral populations swing through day and night.
November 5, 2025 at 3:01 PM
The ocean’s got rhythm — and so do its viruses.
With the Bermuda Atlantic Time-Series (BATS), we dove deep — every 4 to 12 hours — to see how viral populations swing through day and night.
With the Bermuda Atlantic Time-Series (BATS), we dove deep — every 4 to 12 hours — to see how viral populations swing through day and night.
🤩Say hi to #HFScout Dipti Nayak, whose pioneering work on methanogenic archaea (a special group of ancient microbes) is transforming how we understand early life on Earth 🌎 and informing new strategies to address climate change. 1/
October 22, 2025 at 4:42 PM
🤩Say hi to #HFScout Dipti Nayak, whose pioneering work on methanogenic archaea (a special group of ancient microbes) is transforming how we understand early life on Earth 🌎 and informing new strategies to address climate change. 1/
👋Meet #HFScout Roseanna Zia, whose research on colloids (small particles suspended in fluid) has reshaped our understanding of complex fluids, soft matter physics, and the physics of life itself. 1/
October 22, 2025 at 4:39 PM
👋Meet #HFScout Roseanna Zia, whose research on colloids (small particles suspended in fluid) has reshaped our understanding of complex fluids, soft matter physics, and the physics of life itself. 1/
📣Exciting day at the @HypothesisFund! We’re thrilled to recognize two new brilliant scientist Scouts: Roseanna Zia and Dipti Nayak! 1/
October 22, 2025 at 4:30 PM
📣Exciting day at the @HypothesisFund! We’re thrilled to recognize two new brilliant scientist Scouts: Roseanna Zia and Dipti Nayak! 1/
Reposted by Hypothesis Fund
Congrats to @zjahed.bsky.social on receiving a seed grant from the @hypothesisfund.bsky.social to explore mechanisms of aging in cells that don't divide, like those in the brain and heart. Her work could shed new light on the progression of many age-related diseases. today.ucsd.edu/story/uc-san...
UC San Diego Engineer Awarded Hypothesis Fund Grant to Explore Aging in Brain and Heart Cells
Why do some of the body’s most important cells — like those in the brain and heart — age, even though they never divide? Chemical and nano engineering professor Zeinab Jahed has received a seed grant ...
today.ucsd.edu
October 16, 2025 at 4:52 PM
Congrats to @zjahed.bsky.social on receiving a seed grant from the @hypothesisfund.bsky.social to explore mechanisms of aging in cells that don't divide, like those in the brain and heart. Her work could shed new light on the progression of many age-related diseases. today.ucsd.edu/story/uc-san...
🌟New awards alert!✨ We're thrilled to announce new awards in the diverse disciplines of materials science, aging, and RNA biology. Meet these talented scientists and hear from the Scouts who recommended them below!
Learn more: bit.ly/HFAwardees 1/
October 16, 2025 at 4:15 PM
🌟New awards alert!✨ We're thrilled to announce new awards in the diverse disciplines of materials science, aging, and RNA biology. Meet these talented scientists and hear from the Scouts who recommended them below!
Learn more: bit.ly/HFAwardees 1/
Big congrats to HF Awardee @sciencekyle.bsky.social for being awarded the prestigious NIH DP2 award to continue his work on engineering immune cells to tackle cancer. So incredibly proud to have supported the early stages of this groundbreaking science -- go Kyle! 🥳
news.stanford.edu/stories/2025...
news.stanford.edu/stories/2025...
Stanford researchers receive NIH High-Risk, High-Reward grants
This year’s awardees are researching cancer treatments, age-related disease, and much more.
news.stanford.edu
October 9, 2025 at 9:32 PM
Big congrats to HF Awardee @sciencekyle.bsky.social for being awarded the prestigious NIH DP2 award to continue his work on engineering immune cells to tackle cancer. So incredibly proud to have supported the early stages of this groundbreaking science -- go Kyle! 🥳
news.stanford.edu/stories/2025...
news.stanford.edu/stories/2025...
Big congrats to #HFScout @sullivan-lab.bsky.social for receiving an ASM award for his contributions to environmental research! 🎉
ASM is pleased to announce the 2026 ASM Awards & Prize Program recipients—leaders whose research, teaching and innovation are advancing the microbial sciences. Join us in congratulating the recipients! Learn more about the honorees and awards: asm.social/2zX
September 23, 2025 at 11:07 PM
Big congrats to #HFScout @sullivan-lab.bsky.social for receiving an ASM award for his contributions to environmental research! 🎉
Reposted by Hypothesis Fund
🚨 New tool for viral genomics!
Meet CLAE: a high-fidelity Nanopore sequencing strategy that pushes accuracy to Q30, boosts throughput >800 Mb/100 pores, and recovers full-length viral genomes from complex samples 🌊🦠
👉 [https://doi.org/10.1002/advs.202505978]
#viromics #nanopore #genomics
Meet CLAE: a high-fidelity Nanopore sequencing strategy that pushes accuracy to Q30, boosts throughput >800 Mb/100 pores, and recovers full-length viral genomes from complex samples 🌊🦠
👉 [https://doi.org/10.1002/advs.202505978]
#viromics #nanopore #genomics
September 12, 2025 at 3:34 PM
While on an expedition in the Arctic❄️, #HFScout @prakashlab.bsky.social made a fascinating discovery about ice diatoms. Check out his new manuscript!
(To learn more about Manu's quest to see every organism on earth, revisit his episode of The Leap: www.sciencefriday.com/segments/man...)
(To learn more about Manu's quest to see every organism on earth, revisit his episode of The Leap: www.sciencefriday.com/segments/man...)
Did you know tiny algae can "skate" within Arctic sea ice? ⛸️ Our new study in @pnas.org reveals the secret life of ice diatoms: they are actively gliding to navigate the ice! This adds a new dimension to the sea ice ecosystem, revealing an active, dynamic ecological niche. @prakashlab.bsky.social
September 12, 2025 at 1:18 AM
While on an expedition in the Arctic❄️, #HFScout @prakashlab.bsky.social made a fascinating discovery about ice diatoms. Check out his new manuscript!
(To learn more about Manu's quest to see every organism on earth, revisit his episode of The Leap: www.sciencefriday.com/segments/man...)
(To learn more about Manu's quest to see every organism on earth, revisit his episode of The Leap: www.sciencefriday.com/segments/man...)
We turned 3⃣ this year! Our founder & CEO David Sanford reflects on the incredible science we've enabled, and the people who made it possible. Read about our journey:
www.linkedin.com/pulse/three-...
www.linkedin.com/pulse/three-...
Three Years on the Frontiers of Science
The past year has been one of significant growth and validation for the Hypothesis Fund. As we reached our third anniversary earlier this summer, we're celebrating the incredible science we’ve support...
www.linkedin.com
August 27, 2025 at 9:15 PM
We turned 3⃣ this year! Our founder & CEO David Sanford reflects on the incredible science we've enabled, and the people who made it possible. Read about our journey:
www.linkedin.com/pulse/three-...
www.linkedin.com/pulse/three-...
Reposted by Hypothesis Fund
I am excited to share that I received an award from the National Science Foundation!
I'm considering candidates for up to two postdoc positions - reach out by Aug 28th for full consideration.
sites.google.com/uncc.edu/mic...
I'm considering candidates for up to two postdoc positions - reach out by Aug 28th for full consideration.
sites.google.com/uncc.edu/mic...
Luo Lab - Microbial Ecology - join
The Luo Lab is accepting applications for funded Postdoc and PhD opportunities. Details below.
Lab members will have access to state-of-the art wet lab, and computing, and sequencing resources, inclu...
sites.google.com
August 19, 2025 at 1:32 AM
I am excited to share that I received an award from the National Science Foundation!
I'm considering candidates for up to two postdoc positions - reach out by Aug 28th for full consideration.
sites.google.com/uncc.edu/mic...
I'm considering candidates for up to two postdoc positions - reach out by Aug 28th for full consideration.
sites.google.com/uncc.edu/mic...
Reposted by Hypothesis Fund
Congratulations to @bendeskylab.com on being awarded a @hypothesisfund.bsky.social seed grant! He’s asking why some of an animal’s genes are switched on and others off, depending on which parent the genes came from. And how evolution shapes this phenomenon, called genetic imprinting.
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August 19, 2025 at 4:48 PM
Congratulations to @bendeskylab.com on being awarded a @hypothesisfund.bsky.social seed grant! He’s asking why some of an animal’s genes are switched on and others off, depending on which parent the genes came from. And how evolution shapes this phenomenon, called genetic imprinting.
🧠🧬
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Reposted by Hypothesis Fund
Incredibly honored to receive support from the Hypothesis Fund!
🤩 New awards announcement! ✨ We're excited to announce our latest awardees who are tackling bold research that spans immunology, plant biology, and genetics. Learn more about these talented scientists below!
Discover our full portfolio: bit.ly/HFAwardees 1/
Discover our full portfolio: bit.ly/HFAwardees 1/
August 19, 2025 at 4:36 PM
Incredibly honored to receive support from the Hypothesis Fund!
🤩 New awards announcement! ✨ We're excited to announce our latest awardees who are tackling bold research that spans immunology, plant biology, and genetics. Learn more about these talented scientists below!
Discover our full portfolio: bit.ly/HFAwardees 1/
Discover our full portfolio: bit.ly/HFAwardees 1/
August 19, 2025 at 4:24 PM
🤩 New awards announcement! ✨ We're excited to announce our latest awardees who are tackling bold research that spans immunology, plant biology, and genetics. Learn more about these talented scientists below!
Discover our full portfolio: bit.ly/HFAwardees 1/
Discover our full portfolio: bit.ly/HFAwardees 1/
Reposted by Hypothesis Fund
🚨New Marlin Lab publication✨ app.jove.com/v/67112/prof...
In this #JoVE, we share a method for extracting meaningful, uninstructed behavioral readouts from constrained video recording environments (🧵1/2)
Led @brimcr.bsky.social & @AmirLawen, a @zuckermanbrain.bsky.social collab w/ @ItamarKahn.
In this #JoVE, we share a method for extracting meaningful, uninstructed behavioral readouts from constrained video recording environments (🧵1/2)
Led @brimcr.bsky.social & @AmirLawen, a @zuckermanbrain.bsky.social collab w/ @ItamarKahn.
Profiling Maternal Behavior Responses During Whole-Brain Imaging
Recent advancements in whole-brain imaging tools have enabled neuroscientists to investigate how coordinated brain activity processes external cues, ...
app.jove.com
August 18, 2025 at 9:44 PM
🚨New Marlin Lab publication✨ app.jove.com/v/67112/prof...
In this #JoVE, we share a method for extracting meaningful, uninstructed behavioral readouts from constrained video recording environments (🧵1/2)
Led @brimcr.bsky.social & @AmirLawen, a @zuckermanbrain.bsky.social collab w/ @ItamarKahn.
In this #JoVE, we share a method for extracting meaningful, uninstructed behavioral readouts from constrained video recording environments (🧵1/2)
Led @brimcr.bsky.social & @AmirLawen, a @zuckermanbrain.bsky.social collab w/ @ItamarKahn.
Reposted by Hypothesis Fund
Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @natsmb.nature.com🥳 rdcu.be/eBbrH
A massive team effort led by @leonieanton.bsky.social Meseret Haile & Wenjing Cheng in collaboration with Jerzy Dziekan & the Alan Cowman! #TeamTomo
A massive team effort led by @leonieanton.bsky.social Meseret Haile & Wenjing Cheng in collaboration with Jerzy Dziekan & the Alan Cowman! #TeamTomo
Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug
Nature Structural & Molecular Biology - Integrated structural biology approach leveraging in situ cryo-electron tomography reveals molecular details of the native malarial translation...
rdcu.be
August 18, 2025 at 12:13 PM
Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @natsmb.nature.com🥳 rdcu.be/eBbrH
A massive team effort led by @leonieanton.bsky.social Meseret Haile & Wenjing Cheng in collaboration with Jerzy Dziekan & the Alan Cowman! #TeamTomo
A massive team effort led by @leonieanton.bsky.social Meseret Haile & Wenjing Cheng in collaboration with Jerzy Dziekan & the Alan Cowman! #TeamTomo
Big congrats to Hypothesis Fund Awardee @bjmarlin.bsky.social! We're proud early supporters of her research on transgenerational epigenetic inheritance, and can't wait to see what she'll discover next! Go Bianca! 🌟
Congratulations to @bjmarlin.bsky.social on being named a 2025 Pew Biomedical Scholar! Her research dives deep into what is innate, what is learned and what is chosen by biology to be passed down from generation to generation. 🧠 🌟
www.pew.org/en/projects/...
www.pew.org/en/projects/...
August 12, 2025 at 11:15 PM
Big congrats to Hypothesis Fund Awardee @bjmarlin.bsky.social! We're proud early supporters of her research on transgenerational epigenetic inheritance, and can't wait to see what she'll discover next! Go Bianca! 🌟
Reposted by Hypothesis Fund
Evolution’s eye game is wild, but mollusks take it to another level
CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess
It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates
rdcu.be/ezw0t
CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess
It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates
rdcu.be/ezw0t
A genetically tractable non-vertebrate system to study complete camera-type eye regeneration
Nature Communications - Accorsi et al. show that the apple snail Pomacea canaliculata has eyes similar to humans and can fully regenerate them. They then developed genetic tools to establish these...
url.us.m.mimecastprotect.com
August 6, 2025 at 11:21 AM
Evolution’s eye game is wild, but mollusks take it to another level
CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess
It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates
rdcu.be/ezw0t
CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess
It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates
rdcu.be/ezw0t
Reposted by Hypothesis Fund
So excited to participate in this panel discussing the history and future of #PalaeoPERCS and the amazing, inclusive, and absolutely brilliant international community of early career pal(a)eo scientists! Please join us at 15:00 UTC today for this really important discussion!
Next week at #PalaeoPERCS we will be hosting a special seminar celebrating our 5th anniversary. We'll be joined by our past & current committee members. We'd be glad if you could also be a part of this celebration & collective reflection.
Sign up here: paleopercs.com/participate/
(1/4)
Sign up here: paleopercs.com/participate/
(1/4)
July 22, 2025 at 1:38 PM
So excited to participate in this panel discussing the history and future of #PalaeoPERCS and the amazing, inclusive, and absolutely brilliant international community of early career pal(a)eo scientists! Please join us at 15:00 UTC today for this really important discussion!
📣 Bold science alert! We're thrilled to announce our newest awardees whose projects span neuroscience, bacteriology, & synthetic biology. Join us in celebrating them as we showcase their research projects below!
Meet all of our awardees: bit.ly/HFAwardees. 1/
Meet all of our awardees: bit.ly/HFAwardees. 1/
July 17, 2025 at 6:01 PM
📣 Bold science alert! We're thrilled to announce our newest awardees whose projects span neuroscience, bacteriology, & synthetic biology. Join us in celebrating them as we showcase their research projects below!
Meet all of our awardees: bit.ly/HFAwardees. 1/
Meet all of our awardees: bit.ly/HFAwardees. 1/
Reposted by Hypothesis Fund
In the final episode of The Leap, Oceanographer Victoria Orphan (center) and her colleagues embark on one of the deepest science dives ever. Then, things start going awry.
Explore *the entire* 10-part series now, from @hypothesisfund.bsky.social and SciFri: buff.ly/5lNhOmV
Explore *the entire* 10-part series now, from @hypothesisfund.bsky.social and SciFri: buff.ly/5lNhOmV
July 16, 2025 at 11:28 PM
In the final episode of The Leap, Oceanographer Victoria Orphan (center) and her colleagues embark on one of the deepest science dives ever. Then, things start going awry.
Explore *the entire* 10-part series now, from @hypothesisfund.bsky.social and SciFri: buff.ly/5lNhOmV
Explore *the entire* 10-part series now, from @hypothesisfund.bsky.social and SciFri: buff.ly/5lNhOmV
🌊New Episode 🌊 @caltech.edu oceanographer & @hypothesisfund.bsky.social scientific advisor Victoria Orphan was in the #Alvin submersible on her deepest dive yet... when the sub started misbehaving. A deep sea dive you’ll never forget on The Leap👇
Oceanographer Victoria Orphan was living her dream on the Alvin submersible—until the dive took a turn.
In the final episode of "The Leap," what happens when a dive to the bottom of the sea doesn’t go as planned? By @hypothesisfund.bsky.social + SciFri: buff.ly/ltALRPB
In the final episode of "The Leap," what happens when a dive to the bottom of the sea doesn’t go as planned? By @hypothesisfund.bsky.social + SciFri: buff.ly/ltALRPB
July 14, 2025 at 5:35 PM
🌊New Episode 🌊 @caltech.edu oceanographer & @hypothesisfund.bsky.social scientific advisor Victoria Orphan was in the #Alvin submersible on her deepest dive yet... when the sub started misbehaving. A deep sea dive you’ll never forget on The Leap👇
@drkhaynes.bsky.social isn’t trying to fit in. Like when she was invited to a scientific conference & decided to bring a 3’x4’ stretched canvas & live-paint her poster🎨. Listen to her story on The Leap (HF + @scifri.bsky.social): www.sciencefriday.com/segments/eve...
📷: @phylogenomics.bsky.social
📷: @phylogenomics.bsky.social
July 9, 2025 at 4:59 PM
@drkhaynes.bsky.social isn’t trying to fit in. Like when she was invited to a scientific conference & decided to bring a 3’x4’ stretched canvas & live-paint her poster🎨. Listen to her story on The Leap (HF + @scifri.bsky.social): www.sciencefriday.com/segments/eve...
📷: @phylogenomics.bsky.social
📷: @phylogenomics.bsky.social