Alexis Caulier
hemagene.bsky.social
Alexis Caulier
@hemagene.bsky.social
Reposted by Alexis Caulier
Systemic inflammation impairs myelopoiesis and interferon type I responses in humans
www.nature.com/articles/s41...
@natimmunol.bsky.social
April 18, 2025 at 4:34 PM
Reposted by Alexis Caulier
There’s an arms race going on between a disease-causing fungus and its host, and it’s not the one portrayed in HBO’s postapocalyptic series The Last of Us. #ScienceMagArchives scim.ag/42QS3Un
Arms race between ants and fungi has echoes of The Last of Us
Insects are fighting off fungal invaders, but the fungi have some tricks up their sleeve
scim.ag
April 18, 2025 at 5:44 PM
Reposted by Alexis Caulier
The Science Visuals team has been honored with three
@commarts.com Awards of Excellence.

These prestigious awards recognize creative excellence and outstanding execution in visual storytelling. (THREAD 🧵) scim.ag/4jDJ6TY
Science Visuals honored with three Communication Arts Awards
The prestigious awards recognize creative excellence and outstanding execution in visual storytelling.
scim.ag
April 18, 2025 at 7:25 PM
A great ressource from the Khoriaty lab at University of Michigan to understand deeper the molecular regulation of erythropoiesis, this week in @natcomms.nature.com

www.nature.com/articles/s41...
A genome-wide screen identifies genes required for erythroid differentiation - Nature Communications
Using a genome-wide CRISPR knock-out screen, the authors defined the repertoire of genes that are required for proerythroblast survival and for terminal erythroid differentiation.
www.nature.com
April 16, 2025 at 7:42 PM
Reposted by Alexis Caulier
Scalable spatial transcriptomics through computational array reconstruction - @broadinstitute.org go.nature.com/3QYfSDd
Scalable spatial transcriptomics through computational array reconstruction - Nature Biotechnology
An imaging-free spatial transcriptomics method facilitates high-throughput barcode array generation up to centimeter scale.
go.nature.com
April 3, 2025 at 3:05 PM
Our work nicely complements recently released papers from @thenormanlab www.cell.com/cell-systems... and @satijalab www.nature.com/articles/s41... that describe the value of multimodal perturb-seq using CRISPRi in cell lines to decipher gene regulatory networks ! 🧬 🧫
April 3, 2025 at 9:25 PM
Out today in @science.org!
What if you could chart cells' regulatory programs at unprecedented resolution?
In my work with Jorge Martin-Rufino from the @bloodgenes.bsky.social lab, we dissect the genome’s control circuits and find where key genetic variation hides
bit.ly/3YhBMoO
Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes
Most phenotype-associated genetic variants map to noncoding regulatory regions of the human genome, but their mechanisms remain elusive in most cases. We developed a highly efficient strategy, Perturb...
bit.ly
April 3, 2025 at 9:20 PM
Reposted by Alexis Caulier
Congratulations to @danafarber.bsky.social’s Lara Wahlster, MD, PhD, and Nina Weichert-Leahey, MD, for receiving the American Society for Clinical Investigation Emerging-Generation Awards. Read about Dr. Wahlster at bit.ly/4haxdTW and Dr. Weichert-Leahey at bit.ly/4h6BYxL.
March 6, 2025 at 7:27 PM