Helen Chen
@hc327.bsky.social
#iPSC scientist & #organoids engineer for #RareDisease working on disease modeling & precision medicine. @StJudeResearch, @ubc alumnus🇨🇦
Reposted by Helen Chen
As spooky season is upon us 🎃, we have cells that look like spider webs for #FluorescenceFriday 🧪🔬
October 24, 2025 at 7:03 PM
As spooky season is upon us 🎃, we have cells that look like spider webs for #FluorescenceFriday 🧪🔬
Reposted by Helen Chen
🚀 Exciting MSc opp @ UManitoba! Join 2 interdisciplinary labs (bioinformatics + cancer bio) on a CIHR-funded ovarian cancer project. Gain hands-on training in single-cell genomics & molecular biology. See advertisement to apply #GradResearch #Cancer
September 26, 2025 at 3:31 PM
🚀 Exciting MSc opp @ UManitoba! Join 2 interdisciplinary labs (bioinformatics + cancer bio) on a CIHR-funded ovarian cancer project. Gain hands-on training in single-cell genomics & molecular biology. See advertisement to apply #GradResearch #Cancer
Reposted by Helen Chen
Great talk from @hc327.bsky.social at the 7th annual CCP Phenogenomics Conference! Dr Chen shows how rare disease foundations can really facilitate fantastic scientific progress directly helping patient families!
September 12, 2025 at 2:23 PM
Great talk from @hc327.bsky.social at the 7th annual CCP Phenogenomics Conference! Dr Chen shows how rare disease foundations can really facilitate fantastic scientific progress directly helping patient families!
Reposted by Helen Chen
I still can't get over how cool cells can be reaching out and interacting with one another! This depth shaded membrane marker gives us an idea of how dynamic these extensions can be! #FluorescenceFriday 🔬🧪
August 15, 2025 at 2:22 PM
I still can't get over how cool cells can be reaching out and interacting with one another! This depth shaded membrane marker gives us an idea of how dynamic these extensions can be! #FluorescenceFriday 🔬🧪
Excited to share my latest paper from @stjuderesearch.bsky.social , where we leverage patient derived cortical organoids to study UBA5 associated neurodevelopmental disorders.
Scientists developed a patient-derived organoid model for UBA5-associated encephalopathy, revealing stunted GABAergic interneuron growth as a cause of seizures. Boosting activity of the hypomorphic UBA5 gene shows promise as a potential therapy.
May 7, 2025 at 7:26 PM
Excited to share my latest paper from @stjuderesearch.bsky.social , where we leverage patient derived cortical organoids to study UBA5 associated neurodevelopmental disorders.
Reposted by Helen Chen
Its FINALLY here! The first #FluorescenceFriday 🧪🔬out of the Hall lab! We're still in the process of optimizing different fixatives to look for cytonemes and cellular extensions, but a fantastic first time imaging them from Morgan Hiebert!
April 4, 2025 at 9:49 PM
Its FINALLY here! The first #FluorescenceFriday 🧪🔬out of the Hall lab! We're still in the process of optimizing different fixatives to look for cytonemes and cellular extensions, but a fantastic first time imaging them from Morgan Hiebert!
Reposted by Helen Chen
Despite all that is going on, I will not miss a #FluorescenceFriday! ✊ This is a confocal micrograph of a long cytoneme making contact with a recipient NIH3T3 cell (right) to deliver SHH ligand. The 🟣 dots are packages of SHH. Very cool! 🔬 by former postdoc @erichall.bsky.social. 🧪 #SciArt #DevBio
February 21, 2025 at 4:12 PM
Despite all that is going on, I will not miss a #FluorescenceFriday! ✊ This is a confocal micrograph of a long cytoneme making contact with a recipient NIH3T3 cell (right) to deliver SHH ligand. The 🟣 dots are packages of SHH. Very cool! 🔬 by former postdoc @erichall.bsky.social. 🧪 #SciArt #DevBio
Reposted by Helen Chen
Here is an early #FluorescenceFriday post - a 3D render of a developing mouse neural tube showing a signaling filopodium (cytoneme) reaching toward a primary cilium (green) to deliver a cellular signal (SHH, magenta). See alt text for details. Research supported by #NIH #NIGMS 🔬 by Eric Hall. 🧪
January 23, 2025 at 8:12 PM
Here is an early #FluorescenceFriday post - a 3D render of a developing mouse neural tube showing a signaling filopodium (cytoneme) reaching toward a primary cilium (green) to deliver a cellular signal (SHH, magenta). See alt text for details. Research supported by #NIH #NIGMS 🔬 by Eric Hall. 🧪
Reposted by Helen Chen
🧪🧑🔬 We are actively recruiting graduate students in the lab right now at UM!
If you are, or know a student looking to do cool research involving cell signaling, development, and 🔬, please share with your networks. For more information, checkout the link below.
rfhs.myjboard.io/jobs/1054626...
If you are, or know a student looking to do cool research involving cell signaling, development, and 🔬, please share with your networks. For more information, checkout the link below.
rfhs.myjboard.io/jobs/1054626...
MSc or PhD Student Positions: Cytoneme mediated cell-cell communication in development and disease at Hall Lab
rfhs.myjboard.io
January 21, 2025 at 6:34 PM
🧪🧑🔬 We are actively recruiting graduate students in the lab right now at UM!
If you are, or know a student looking to do cool research involving cell signaling, development, and 🔬, please share with your networks. For more information, checkout the link below.
rfhs.myjboard.io/jobs/1054626...
If you are, or know a student looking to do cool research involving cell signaling, development, and 🔬, please share with your networks. For more information, checkout the link below.
rfhs.myjboard.io/jobs/1054626...
Great lab! Great opportunity! Highly recommend!
🧪🧑🔬 We are actively recruiting graduate students in the lab right now at UM!
If you are, or know a student looking to do cool research involving cell signaling, development, and 🔬, please share with your networks. For more information, checkout the link below.
rfhs.myjboard.io/jobs/1054626...
If you are, or know a student looking to do cool research involving cell signaling, development, and 🔬, please share with your networks. For more information, checkout the link below.
rfhs.myjboard.io/jobs/1054626...
MSc or PhD Student Positions: Cytoneme mediated cell-cell communication in development and disease at Hall Lab
rfhs.myjboard.io
January 22, 2025 at 12:19 AM
Great lab! Great opportunity! Highly recommend!
Reposted by Helen Chen
The Mefford Lab is #hiring, come join us! @hcmefford.bsky.social
We have TWO positions open:
(1) *Lead Researcher/Scientist* who will have the opportunity to lead 2D and 3D #epilepsy #genetics modeling to inform better targeted treatments for kids. 🧠🧬💜
talent.stjude.org/careers/jobs...
We have TWO positions open:
(1) *Lead Researcher/Scientist* who will have the opportunity to lead 2D and 3D #epilepsy #genetics modeling to inform better targeted treatments for kids. 🧠🧬💜
talent.stjude.org/careers/jobs...
Lead Researcher / Scientist - Mefford Lab in Memphis, Tennessee | St. Jude Careers
St. Jude Careers is hiring a Lead Researcher / Scientist - Mefford Lab in Memphis, Tennessee. Review all of the job details and apply today!
talent.stjude.org
December 4, 2024 at 4:18 PM
The Mefford Lab is #hiring, come join us! @hcmefford.bsky.social
We have TWO positions open:
(1) *Lead Researcher/Scientist* who will have the opportunity to lead 2D and 3D #epilepsy #genetics modeling to inform better targeted treatments for kids. 🧠🧬💜
talent.stjude.org/careers/jobs...
We have TWO positions open:
(1) *Lead Researcher/Scientist* who will have the opportunity to lead 2D and 3D #epilepsy #genetics modeling to inform better targeted treatments for kids. 🧠🧬💜
talent.stjude.org/careers/jobs...