Håvard Lindholm
@havardtl.bsky.social
Bioinformatics, transposable elements, immunology and more!
Department of Pathology, Oslo University Hospital
Department of Pathology, Oslo University Hospital
Reposted by Håvard Lindholm
Excited to have this paper out today!
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape."
It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others!
www.cell.com/cell-genomic...
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape."
It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others!
www.cell.com/cell-genomic...
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape
An emerging hallmark of disease is transcription of pathogen-associated molecular
patterns from within the genome–known as viral mimicry. We propose a statistical physics
framework to measure “selecti...
www.cell.com
September 26, 2025 at 2:36 PM
Excited to have this paper out today!
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape."
It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others!
www.cell.com/cell-genomic...
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape."
It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others!
www.cell.com/cell-genomic...
Nice to see this story out! The idea that viral mimicry is an intrinsic feedback mechanism for sensing cellular dysregulation is fascinating and this paper explores this idea really well.
It was inspiring to be part of this collaborative work. Thanks to @bengrbm.bsky.social and the rest!
It was inspiring to be part of this collaborative work. Thanks to @bengrbm.bsky.social and the rest!
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape
An emerging hallmark of disease is transcription of pathogen-associated molecular
patterns from within the genome–known as viral mimicry. We propose a statistical physics
framework to measure “selecti...
www.cell.com
September 25, 2025 at 8:20 AM
Nice to see this story out! The idea that viral mimicry is an intrinsic feedback mechanism for sensing cellular dysregulation is fascinating and this paper explores this idea really well.
It was inspiring to be part of this collaborative work. Thanks to @bengrbm.bsky.social and the rest!
It was inspiring to be part of this collaborative work. Thanks to @bengrbm.bsky.social and the rest!
Reposted by Håvard Lindholm
Congratulations to Dr. Daniel De Carvalho (@daniel-decarvalho.bsky.social) on winning the 2025 Gairdner Momentum Award! 🎉
His impactful work in cancer epigenetics is revolutionizing early detection and treatment. A well-deserved honour! 👏
🔗 www.uhnresearch.ca/news/gairdne...
His impactful work in cancer epigenetics is revolutionizing early detection and treatment. A well-deserved honour! 👏
🔗 www.uhnresearch.ca/news/gairdne...
April 11, 2025 at 2:13 PM
Congratulations to Dr. Daniel De Carvalho (@daniel-decarvalho.bsky.social) on winning the 2025 Gairdner Momentum Award! 🎉
His impactful work in cancer epigenetics is revolutionizing early detection and treatment. A well-deserved honour! 👏
🔗 www.uhnresearch.ca/news/gairdne...
His impactful work in cancer epigenetics is revolutionizing early detection and treatment. A well-deserved honour! 👏
🔗 www.uhnresearch.ca/news/gairdne...
Reposted by Håvard Lindholm
Our recent work on Viral mimicry escape in Ovarian Cancer is out at Cancer Discovery: aacrjournals.org/cancerdiscov...
Chronic viral mimicry induction following p53 loss promotes immune evasion
Abstract. Epigenetic therapies facilitate transcription of immunogenic repetitive elements that cull cancer cells through ‘viral mimicry’ responses. Paradoxically, cancer-initiating events also facili...
aacrjournals.org
January 17, 2025 at 2:27 PM
Our recent work on Viral mimicry escape in Ovarian Cancer is out at Cancer Discovery: aacrjournals.org/cancerdiscov...