Guramrit Singh
@guramrit.bsky.social
Associate professor at Ohio State; interested in understanding RNA processing, surveillance, and decay.
https://u.osu.edu/singhlab/
https://u.osu.edu/singhlab/
Interesting read:
www.nytimes.com/2025/04/14/o...
www.nytimes.com/2025/04/14/o...
Opinion | This Is How Universities Can Escape Trump’s Trap, If They Dare
It’s been tried in other countries facing authoritarian crackdowns. It works.
www.nytimes.com
April 14, 2025 at 3:23 PM
Interesting read:
www.nytimes.com/2025/04/14/o...
www.nytimes.com/2025/04/14/o...
Reposted by Guramrit Singh
📣 Across the U.S., cuts to federal funding for health research are projected to cause losses of $16B and 68,500 jobs. How will YOUR area be impacted?
Excited to share SCIMaP, a website that our team has created to communicate the impact of funding cuts. #PsychSciSky #MedicalSky
scienceimpacts.org
Excited to share SCIMaP, a website that our team has created to communicate the impact of funding cuts. #PsychSciSky #MedicalSky
scienceimpacts.org
SCiMaP
scienceimpacts.org
March 27, 2025 at 8:22 PM
📣 Across the U.S., cuts to federal funding for health research are projected to cause losses of $16B and 68,500 jobs. How will YOUR area be impacted?
Excited to share SCIMaP, a website that our team has created to communicate the impact of funding cuts. #PsychSciSky #MedicalSky
scienceimpacts.org
Excited to share SCIMaP, a website that our team has created to communicate the impact of funding cuts. #PsychSciSky #MedicalSky
scienceimpacts.org
Reposted by Guramrit Singh
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
February 12, 2025 at 5:04 PM
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Reposted by Guramrit Singh
Will universities finally speak up now?
Or are they still "working behind the scenes"
Texted with many academic colleagues last night, the consensus is, if these cuts hold, many of us can no longer have a career in academia.
This will spur mass exodus.
www.science.org/content/arti...
Or are they still "working behind the scenes"
Texted with many academic colleagues last night, the consensus is, if these cuts hold, many of us can no longer have a career in academia.
This will spur mass exodus.
www.science.org/content/arti...
NIH slashes overhead payments for research, sparking outrage
Move to cut indirect cost rate to 15% could cost universities billions of dollars
www.science.org
February 8, 2025 at 12:41 PM
Will universities finally speak up now?
Or are they still "working behind the scenes"
Texted with many academic colleagues last night, the consensus is, if these cuts hold, many of us can no longer have a career in academia.
This will spur mass exodus.
www.science.org/content/arti...
Or are they still "working behind the scenes"
Texted with many academic colleagues last night, the consensus is, if these cuts hold, many of us can no longer have a career in academia.
This will spur mass exodus.
www.science.org/content/arti...
Bit late to repost but really happy to share Caleb's dissertation work! Turns out there is more to the relationship between splicing and NMD. Read the preprint for more!
My graduate work from the Singh lab is now out on bioRxiv. In it we look at the impacts on nonsense mediated mRNA decay when the spliceosome is disrupted in different ways.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Direct and indirect effects of spliceosome disruption compromise gene regulation by Nonsense-Mediated mRNA Decay
Pre-mRNA splicing, carried out in the nucleus by a large ribonucleoprotein machine known as the spliceosome, is functionally and physically coupled to the mRNA surveillance pathway in the cytoplasm ca...
www.biorxiv.org
January 15, 2025 at 7:33 PM
Bit late to repost but really happy to share Caleb's dissertation work! Turns out there is more to the relationship between splicing and NMD. Read the preprint for more!
First bsky post! I'm looking for suggestions/tips for a successful+fun flipped classroom. Anita Hopper plans to do this in our RNA biology course using Rob Singer's iBiology lecture on mRNA localization. Lot out there on how flipped classrooms enhance learning but not much on how to do them well.
January 15, 2025 at 7:27 PM
First bsky post! I'm looking for suggestions/tips for a successful+fun flipped classroom. Anita Hopper plans to do this in our RNA biology course using Rob Singer's iBiology lecture on mRNA localization. Lot out there on how flipped classrooms enhance learning but not much on how to do them well.
Reposted by Guramrit Singh
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics
ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...
www.nature.com
November 27, 2024 at 4:13 AM
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Guramrit Singh
