Alex Grossman
@grossmanmicrobio.bsky.social
Heavy Metal Microbiologist. Interested in host/microbe symbiosis. Postdoctoral researcher at the ADA Forsyth institute in the Lab of Dr. Batbileg Bor
Hello everyone, take a look at my cool bugs from the Microbial Dark Matter phylum Saccharibacteria! These ultrasmall bacteria (in green) track down Actinobacteria hosts (not in green) and grow on the host cell envelope.
For the first time, scientists have performed targeted mutations on an episymbiosis-determining pathway. In a new study on Saccharibacteria, AFI researchers used advanced techniques to observe pili that drive motility and host attachment.
@batbilegbor.bsky.social
forsyth.org/saccharibact...
@batbilegbor.bsky.social
forsyth.org/saccharibact...
October 15, 2025 at 5:01 PM
Hello everyone, take a look at my cool bugs from the Microbial Dark Matter phylum Saccharibacteria! These ultrasmall bacteria (in green) track down Actinobacteria hosts (not in green) and grow on the host cell envelope.
Reposted by Alex Grossman
Exciting progress! In our new preprint, we show that episymbiont Saccharibacteria can directly modulate epithelial immunity—a big step in understanding how these elusive microbes interact with the human host. Kudos to Deepak Chouhan and our amazing collaborators! www.biorxiv.org/content/10.1...
June 3, 2025 at 12:30 PM
Exciting progress! In our new preprint, we show that episymbiont Saccharibacteria can directly modulate epithelial immunity—a big step in understanding how these elusive microbes interact with the human host. Kudos to Deepak Chouhan and our amazing collaborators! www.biorxiv.org/content/10.1...
New paper out! We searched for cargo across thousands of Type 11 Secretion Systems (T11SS) in Proteobacteria and uncovered 2,500+ predicted secreted proteins, including 6 novel cargo types, with experimental verification of a new surface lipoprotein, Pls. doi.org/10.1099/mgen.0.001406
May 21, 2025 at 4:40 PM
New paper out! We searched for cargo across thousands of Type 11 Secretion Systems (T11SS) in Proteobacteria and uncovered 2,500+ predicted secreted proteins, including 6 novel cargo types, with experimental verification of a new surface lipoprotein, Pls. doi.org/10.1099/mgen.0.001406
Reposted by Alex Grossman
Excited to share our new preprint on the detailed investigation of Type 4 pili in epibiont oral Saccharibacteria! Led by Alex Grossman from our lab, and with Jun Liu (Yale), Jeff McLean (UW) and Xuesong He. Check it out: biorxiv.org/content/10.1...
December 4, 2024 at 11:09 AM
Excited to share our new preprint on the detailed investigation of Type 4 pili in epibiont oral Saccharibacteria! Led by Alex Grossman from our lab, and with Jun Liu (Yale), Jeff McLean (UW) and Xuesong He. Check it out: biorxiv.org/content/10.1...