Gingras lab
@gingraslab.bsky.social
Signal transduction, systems biology and proteomics lab focusing on cancer @Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health, Toronto, https://gingraslab.org. (Anne-Claude is also VP of Research @ Sinai Health) #TeamMassSpec
Reposted by Gingras lab
Great collaboration with @gingraslab.bsky.social
& congrats to lead author Vesal.
Paper: www.nature.com/articles/s41...
Thanks to @sinaihealth.bsky.social
& congrats to lead author Vesal.
Paper: www.nature.com/articles/s41...
Thanks to @sinaihealth.bsky.social
October 23, 2025 at 1:40 PM
Great collaboration with @gingraslab.bsky.social
& congrats to lead author Vesal.
Paper: www.nature.com/articles/s41...
Thanks to @sinaihealth.bsky.social
& congrats to lead author Vesal.
Paper: www.nature.com/articles/s41...
Thanks to @sinaihealth.bsky.social
Reposted by Gingras lab
ICYM
A new paper from @kieranrcampbell.bsky.social & @gingraslab.bsky.social labs describes a new tool for efficient bait selection for BioID-based sub-cellular proteome mapping.
👏👏👇👇
A new paper from @kieranrcampbell.bsky.social & @gingraslab.bsky.social labs describes a new tool for efficient bait selection for BioID-based sub-cellular proteome mapping.
👏👏👇👇
Great collaboration with @gingraslab.bsky.social
& congrats to lead author Vesal.
Paper: www.nature.com/articles/s41...
Thanks to @sinaihealth.bsky.social
& congrats to lead author Vesal.
Paper: www.nature.com/articles/s41...
Thanks to @sinaihealth.bsky.social
November 7, 2025 at 10:44 PM
ICYM
A new paper from @kieranrcampbell.bsky.social & @gingraslab.bsky.social labs describes a new tool for efficient bait selection for BioID-based sub-cellular proteome mapping.
👏👏👇👇
A new paper from @kieranrcampbell.bsky.social & @gingraslab.bsky.social labs describes a new tool for efficient bait selection for BioID-based sub-cellular proteome mapping.
👏👏👇👇
⏳Less than 2 weeks left to apply for 4️⃣ faculty positions in our collaborative research institute in Toronto. Don't miss this opportunity! ⤵️
⏰Reminder: There's still time to apply!
LTRI is hiring two outstanding Principal Investigators in Population Health Data Science.
Find out more and apply by October 20th, 2025 ➡️ apply.interfolio.com/172529
LTRI is hiring two outstanding Principal Investigators in Population Health Data Science.
Find out more and apply by October 20th, 2025 ➡️ apply.interfolio.com/172529
October 7, 2025 at 4:09 AM
⏳Less than 2 weeks left to apply for 4️⃣ faculty positions in our collaborative research institute in Toronto. Don't miss this opportunity! ⤵️
Reposted by Gingras lab
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
January 17, 2025 at 6:43 PM
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
Reposted by Gingras lab
We leveraged a #BioID screen conceived by @pmresearch-uhn.bsky.social Noboru Ishiyama/Mitsu Ikura and @gingraslab.bsky.social —finding candidates that bind OPEN vs closed alpha-cat. A reasonable candidate was LZTS2—previously implicated in #abscission, but poorly understood. 6/12
January 10, 2025 at 9:19 PM
We leveraged a #BioID screen conceived by @pmresearch-uhn.bsky.social Noboru Ishiyama/Mitsu Ikura and @gingraslab.bsky.social —finding candidates that bind OPEN vs closed alpha-cat. A reasonable candidate was LZTS2—previously implicated in #abscission, but poorly understood. 6/12
Reposted by Gingras lab
Looking forward to the monthly on-line seminars organized by the Protein Modules Community @pmc-modularity.bsky.social and talks on SLiMs, systems biology, signaling, computational biology and much more. First talks by Dr Gogl @teamgogl.bsky.social and Dr Dionne @gingraslab.bsky.social.
Join us for our new online seminar series, featuring two talks on protein modules every month! The first session kicks off at 6pm CET Feb 10 with Dr. Gergő Gógl and Dr. Ugo Dionne.
Register to attend: tinyurl.com/register-pmc-seminar
Register to attend: tinyurl.com/register-pmc-seminar
January 15, 2025 at 5:59 PM
Looking forward to the monthly on-line seminars organized by the Protein Modules Community @pmc-modularity.bsky.social and talks on SLiMs, systems biology, signaling, computational biology and much more. First talks by Dr Gogl @teamgogl.bsky.social and Dr Dionne @gingraslab.bsky.social.
It's a great start to the new year for @kieranrcampbell.bsky.social , @hartjackson.bsky.social and their amazing teams! See their important paper "Segmentation aware probabilistic phenotyping of single-cell spatial protein expression data" 👏
How can we quantify single cell expression from multiplexed imaging datasets given segmentation errors?
To help tackle this, we introduce evaluation metrics, a gold-standard dataset, and STARLING—a new probabilistic machine learning method (1/4)
www.nature.com/articles/s41...
To help tackle this, we introduce evaluation metrics, a gold-standard dataset, and STARLING—a new probabilistic machine learning method (1/4)
www.nature.com/articles/s41...
Segmentation aware probabilistic phenotyping of single-cell spatial protein expression data - Nature Communications
Spatial expression assays are affected by segmentation errors leading to difficulty interpreting cell types. Here, the authors introduce a machine learning model to infer cell types accounting for suc...
www.nature.com
January 8, 2025 at 2:13 AM
It's a great start to the new year for @kieranrcampbell.bsky.social , @hartjackson.bsky.social and their amazing teams! See their important paper "Segmentation aware probabilistic phenotyping of single-cell spatial protein expression data" 👏
New year, new job? A position of 🧪 🦠 Clinical Diagnostics Project Manager 🦠 🧪 is available with our pandemic preparedness project PRECISE at Sinai Health in Toronto (closes Jan 12) - have a look at the position and apply here:
apply.interfolio.com/160789.
apply.interfolio.com/160789.
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
January 5, 2025 at 5:36 PM
New year, new job? A position of 🧪 🦠 Clinical Diagnostics Project Manager 🦠 🧪 is available with our pandemic preparedness project PRECISE at Sinai Health in Toronto (closes Jan 12) - have a look at the position and apply here:
apply.interfolio.com/160789.
apply.interfolio.com/160789.
Reposted by Gingras lab
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
December 16, 2024 at 11:50 AM
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
Reposted by Gingras lab
Download our database of 313 different postdoctoral fellowships.
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
November 16, 2024 at 7:05 PM
Download our database of 313 different postdoctoral fellowships.
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download our database here: research.jhu.edu/rdt/funding-...
Great opportunity 🧪 to set up your lab at a fantastic institution in downtown Toronto 🇨🇦 and be my neighbour ⬇️
We are recruiting! Princess Margaret Cancer Centre in Toronto is recruiting an early career cancer research scientist at Assistant Professor level. Apply! Spread the word!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Scientist I - Cancer Biology - Toronto (City), Ontario (CA) job with Princess Margaret Cancer Centre | 12831982
Princess Margaret seeks early-career faculty scientists to establish research programs in Cancer Biology - broadly defined.
www.nature.com
November 16, 2024 at 4:14 PM
Great opportunity 🧪 to set up your lab at a fantastic institution in downtown Toronto 🇨🇦 and be my neighbour ⬇️
Reposted by Gingras lab
Scientists in Proteomics Starter Pack! 🧪
go.bsky.app/3XETWrh
Got suggestions? Drop them in the comments!
go.bsky.app/3XETWrh
Got suggestions? Drop them in the comments!
October 28, 2024 at 6:36 PM
Scientists in Proteomics Starter Pack! 🧪
go.bsky.app/3XETWrh
Got suggestions? Drop them in the comments!
go.bsky.app/3XETWrh
Got suggestions? Drop them in the comments!
Reposted by Gingras lab
(1/8) 🚀 Excited to share our findings on a large-scale ChIP-seq assay for 166 previously uncharacterized human transcription factors (TFs) and their roles in both regulatory regions, and more strikingly, the “dark matter” genome. 🌌 doi.org/10.1101/2024....
Extensive binding of uncharacterized human transcription factors to genomic dark matter
Most of the human genome is thought to be non-functional, and includes large segments often referred to as “dark matter” DNA. The genome also encodes hundreds of putative and poorly characterized tran...
doi.org
November 15, 2024 at 7:02 PM
(1/8) 🚀 Excited to share our findings on a large-scale ChIP-seq assay for 166 previously uncharacterized human transcription factors (TFs) and their roles in both regulatory regions, and more strikingly, the “dark matter” genome. 🌌 doi.org/10.1101/2024....
Come join us in Toronto! ⬇️ Great collaborative research community and awesome colleagues (@farmgirlphd.bsky.social is a superb example!). The winters are not so bad either, and the summers are great (disclaimer: I am from Quebec City...).🧪🎓
Please share broadly! We (Molecular Genetics, University of Toronto) are looking for a new faculty member! Deadline Dec 19. Those working on model organisms and using genomics, computational and systems approaches are strongly encouraged to apply! Reach out w/ Qs!
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...
Assistant Professor - Molecular Biology and Genetics
Assistant Professor - Molecular Biology and Genetics
jobs.utoronto.ca
November 15, 2024 at 2:28 AM
Come join us in Toronto! ⬇️ Great collaborative research community and awesome colleagues (@farmgirlphd.bsky.social is a superb example!). The winters are not so bad either, and the summers are great (disclaimer: I am from Quebec City...).🧪🎓
The first post here is a happy one! Linking to recent PhD 🎓Dr. Jon Roth's thesis work is online today at Molecular Cell. authors.elsevier.com/c/1iDJf3vVUP... . Also see the feature on Sinai Health's page www.sinaihealth.ca/news/milesto... 🎆 To Jon, Ulrich and colleagues.
Study shows brain-specific protein variants often switch preference for interacting partners - Sinai...
www.sinaihealth.ca
December 7, 2023 at 5:45 PM
The first post here is a happy one! Linking to recent PhD 🎓Dr. Jon Roth's thesis work is online today at Molecular Cell. authors.elsevier.com/c/1iDJf3vVUP... . Also see the feature on Sinai Health's page www.sinaihealth.ca/news/milesto... 🎆 To Jon, Ulrich and colleagues.