Douglas Gibson
@gibsonlab.bsky.social
Principal Investigator & Sir Henry Dale Fellow
Investigating how hormones and inflammation affect women's reproductive health
Investigating how hormones and inflammation affect women's reproductive health
Pinned
Douglas Gibson
@gibsonlab.bsky.social
· May 27
Steroid Metabolome Profiling Identifies a Unique Androgen Hormone Signature Associated with Endometriosis
Endometriosis is a chronic, hormone-dependent condition that affects 190 million women worldwide. There are no validated biomarkers for endometriosis and this delays diagnosis and treatment.
We perfo...
www.medrxiv.org
We're very excited about this work! Using steroid metabolome profiling we found a unique hormone signature that could be used as a potential non-invasive diagnostic test for endometriosis. Please check out and share the preprint #endometriosis www.medrxiv.org/content/10.1...
Reposted by Douglas Gibson
Steroid Metabolome Profiling Identifies a Unique Androgen Hormone Signature Associated with Endometriosis https://www.medrxiv.org/content/10.1101/2025.05.24.25328281v1
May 26, 2025 at 12:13 AM
Steroid Metabolome Profiling Identifies a Unique Androgen Hormone Signature Associated with Endometriosis https://www.medrxiv.org/content/10.1101/2025.05.24.25328281v1
We're very excited about this work! Using steroid metabolome profiling we found a unique hormone signature that could be used as a potential non-invasive diagnostic test for endometriosis. Please check out and share the preprint #endometriosis www.medrxiv.org/content/10.1...
Steroid Metabolome Profiling Identifies a Unique Androgen Hormone Signature Associated with Endometriosis
Endometriosis is a chronic, hormone-dependent condition that affects 190 million women worldwide. There are no validated biomarkers for endometriosis and this delays diagnosis and treatment.
We perfo...
www.medrxiv.org
May 27, 2025 at 2:30 PM
We're very excited about this work! Using steroid metabolome profiling we found a unique hormone signature that could be used as a potential non-invasive diagnostic test for endometriosis. Please check out and share the preprint #endometriosis www.medrxiv.org/content/10.1...
Reposted by Douglas Gibson
What a day! Incredible energy & inspiring conversations at the #wce2025 joint WES/WERF #Endometriosis Interdisciplinary Research Directions Workshop. So much momentum - and so much important work ahead
May 25, 2025 at 11:26 PM
What a day! Incredible energy & inspiring conversations at the #wce2025 joint WES/WERF #Endometriosis Interdisciplinary Research Directions Workshop. So much momentum - and so much important work ahead
Reposted by Douglas Gibson
To wrap up #EndometriosisActionMonth, we wanted to share our visit to ScotParl last week. Ann & Priscilla represented ENDO1000 as honored guests of Endometriosis UK.
Speakers were optimistic that Scotland could siginficantly reduce diagnosis time by 2030 - down to under a year 🤞
Speakers were optimistic that Scotland could siginficantly reduce diagnosis time by 2030 - down to under a year 🤞
March 31, 2025 at 9:37 AM
To wrap up #EndometriosisActionMonth, we wanted to share our visit to ScotParl last week. Ann & Priscilla represented ENDO1000 as honored guests of Endometriosis UK.
Speakers were optimistic that Scotland could siginficantly reduce diagnosis time by 2030 - down to under a year 🤞
Speakers were optimistic that Scotland could siginficantly reduce diagnosis time by 2030 - down to under a year 🤞
A great week in Charlotte at #SRI2025 full of amazing science and great discussions. Hopefully everyone enjoyed the programme we put together for the endometrial satellite meeting. Special thanks to our speakers and moderators!
March 28, 2025 at 6:33 PM
A great week in Charlotte at #SRI2025 full of amazing science and great discussions. Hopefully everyone enjoyed the programme we put together for the endometrial satellite meeting. Special thanks to our speakers and moderators!
Reposted by Douglas Gibson
👩🏾🔬 Lab alumna Antonia Cuff wondered about the role of #ILC3 in the uterine mucosa.
🧪 ILC3 are most numerous & active at times of repair & regeneration
🧪 They with epithelial and endothelial cells
🧪 But do this less in ppl with #endometriosis
👀 Early access, out today!
#ImmunoSky #ReproSky
🧪 ILC3 are most numerous & active at times of repair & regeneration
🧪 They with epithelial and endothelial cells
🧪 But do this less in ppl with #endometriosis
👀 Early access, out today!
#ImmunoSky #ReproSky
Dynamic roles of ILC3 in endometrial repair and regeneration
AbstractBackground. Innate lymphoid cells (ILC) are prominent in the human uterine mucosa and play physiological roles in pregnancy. ILC3 are the second-mo
academic.oup.com
March 28, 2025 at 7:54 AM
👩🏾🔬 Lab alumna Antonia Cuff wondered about the role of #ILC3 in the uterine mucosa.
🧪 ILC3 are most numerous & active at times of repair & regeneration
🧪 They with epithelial and endothelial cells
🧪 But do this less in ppl with #endometriosis
👀 Early access, out today!
#ImmunoSky #ReproSky
🧪 ILC3 are most numerous & active at times of repair & regeneration
🧪 They with epithelial and endothelial cells
🧪 But do this less in ppl with #endometriosis
👀 Early access, out today!
#ImmunoSky #ReproSky
On the train to Newcastle this morning before changing to get to Oxford for a viva. The views down the east coast did not disappoint. Let's hope the cross-country service doesn't either!
February 24, 2025 at 8:07 AM
On the train to Newcastle this morning before changing to get to Oxford for a viva. The views down the east coast did not disappoint. Let's hope the cross-country service doesn't either!
Reposted by Douglas Gibson
Gave some advice yesterday on how to respond to #reviewers to #proposals and was encouraging people to contact mentors with experience of the specific call to sense check responses. But aware not everyone has this pool to hand, so a few of the headlines from conversation. Please chip in.
January 24, 2025 at 2:47 PM
Gave some advice yesterday on how to respond to #reviewers to #proposals and was encouraging people to contact mentors with experience of the specific call to sense check responses. But aware not everyone has this pool to hand, so a few of the headlines from conversation. Please chip in.
Reposted by Douglas Gibson
"there’s been a complete reframing of this disorder as a neuroinflammatory whole-body condition" - CRH's Philippa Saunders spoke to Scientific American about changing understanding of #endometriosis away from it being purely gynaecological www.scientificamerican.com/article/pain...
Painful Endometriosis Can Affect the Whole Body, Not Only the Pelvis
This disease is now genetically linked to widespread inflammation, asthma, migraines, and more
www.scientificamerican.com
January 24, 2025 at 10:20 AM
"there’s been a complete reframing of this disorder as a neuroinflammatory whole-body condition" - CRH's Philippa Saunders spoke to Scientific American about changing understanding of #endometriosis away from it being purely gynaecological www.scientificamerican.com/article/pain...