Garrett Fogo
@garrettfogo.bsky.social
Postdoc, Brigham and Women’s Hospital
Young-Pearse Lab • NIA K00 Fellow • Umich PhD
Young-Pearse Lab • NIA K00 Fellow • Umich PhD
Reposted by Garrett Fogo
Our study “Genetic and proteomic analysis identifies BAG3 as an amyloid‑responsive regulator of neuronal proteostasis" was published in Acta Neuropathologica this week! Congratulations to lead author Zach Augur, who will be defending his thesis later this week!!
link.springer.com/epdf/10.1007...
link.springer.com/epdf/10.1007...
Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis
link.springer.com
October 15, 2025 at 2:08 PM
Our study “Genetic and proteomic analysis identifies BAG3 as an amyloid‑responsive regulator of neuronal proteostasis" was published in Acta Neuropathologica this week! Congratulations to lead author Zach Augur, who will be defending his thesis later this week!!
link.springer.com/epdf/10.1007...
link.springer.com/epdf/10.1007...
Reposted by Garrett Fogo
New TYP lab publication from co-authors
Zach Augur and @garrettfogo.bsky.social
on deciphering the function of Optineurin in iPSC-derived Neurons and Astrocytes! This will be the first of 3 first-author publications from Zach's PhD thesis! link.springer.com/article/10.1...
Zach Augur and @garrettfogo.bsky.social
on deciphering the function of Optineurin in iPSC-derived Neurons and Astrocytes! This will be the first of 3 first-author publications from Zach's PhD thesis! link.springer.com/article/10.1...
Optineurin deficiency disrupts phosphorylated tau proteostasis and clusterin expression in human neurons - Acta Neuropathologica Communications
Optineurin (OPTN) is an autophagy adaptor protein involved in selective autophagy, including aggrephagy and mitophagy. Pathogenic mutations in OPTN have also been linked to amyotrophic lateral scleros...
link.springer.com
September 8, 2025 at 2:13 PM
New TYP lab publication from co-authors
Zach Augur and @garrettfogo.bsky.social
on deciphering the function of Optineurin in iPSC-derived Neurons and Astrocytes! This will be the first of 3 first-author publications from Zach's PhD thesis! link.springer.com/article/10.1...
Zach Augur and @garrettfogo.bsky.social
on deciphering the function of Optineurin in iPSC-derived Neurons and Astrocytes! This will be the first of 3 first-author publications from Zach's PhD thesis! link.springer.com/article/10.1...
Thankful to have contributed to this great review by Katlynn Emaus from @sandersonlab.bsky.social on cardiolipin in mitochondrial dynamics and mitohagy
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The role of cardiolipin in mitochondrial dynamics and quality control in neuronal ischemia/reperfusion injury - Cell Death & Disease
Cell Death & Disease - The role of cardiolipin in mitochondrial dynamics and quality control in neuronal ischemia/reperfusion injury
www.nature.com
July 6, 2025 at 5:53 PM
Thankful to have contributed to this great review by Katlynn Emaus from @sandersonlab.bsky.social on cardiolipin in mitochondrial dynamics and mitohagy
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Garrett Fogo
Thrilled to share my first first-author paper is out
@cp-neuron.bsky.social! We show that Alzheimer's disease protective CLU alleles upregulate CLU in response to neuropathology, dampening inflammatory signaling between microglia and astrocytes.
Read here www.sciencedirect.com/science/arti...
@cp-neuron.bsky.social! We show that Alzheimer's disease protective CLU alleles upregulate CLU in response to neuropathology, dampening inflammatory signaling between microglia and astrocytes.
Read here www.sciencedirect.com/science/arti...
CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density
Genetic studies implicate clusterin (CLU) in the pathogenesis of Alzheimer’s disease (AD), yet its precise molecular impact remains unclear. Through u…
www.sciencedirect.com
April 30, 2025 at 3:51 PM
Thrilled to share my first first-author paper is out
@cp-neuron.bsky.social! We show that Alzheimer's disease protective CLU alleles upregulate CLU in response to neuropathology, dampening inflammatory signaling between microglia and astrocytes.
Read here www.sciencedirect.com/science/arti...
@cp-neuron.bsky.social! We show that Alzheimer's disease protective CLU alleles upregulate CLU in response to neuropathology, dampening inflammatory signaling between microglia and astrocytes.
Read here www.sciencedirect.com/science/arti...
The final bit of my PhD work from the Sanderson Lab is now out in iScience!
Agent-based modeling of neuronal mitochondrial dynamics using intrinsic variables of individual mitochondria: iScience www.cell.com/iscience/ful...
Agent-based modeling of neuronal mitochondrial dynamics using intrinsic variables of individual mitochondria: iScience www.cell.com/iscience/ful...
Agent-based modeling of neuronal mitochondrial dynamics using intrinsic variables of individual mitochondria
Mitochondrial networks undergo remodeling to regulate form and function. The dynamic
nature of mitochondria is maintained by the dueling processes of mitochondrial fission
and fusion. Dysfunctional mi...
www.cell.com
April 9, 2025 at 12:36 PM
The final bit of my PhD work from the Sanderson Lab is now out in iScience!
Agent-based modeling of neuronal mitochondrial dynamics using intrinsic variables of individual mitochondria: iScience www.cell.com/iscience/ful...
Agent-based modeling of neuronal mitochondrial dynamics using intrinsic variables of individual mitochondria: iScience www.cell.com/iscience/ful...
Happy to share a large part of my PhD work that is now published in Autophagy!
www.tandfonline.com/doi/full/10....
www.tandfonline.com/doi/full/10....
Mitochondrial dynamics and quality control regulate proteostasis in neuronal ischemia-reperfusion
Mitochondrial damage and dysfunction are hallmarks of neuronal injury during cerebral ischemia-reperfusion (I/R). Critical mitochondrial functions including energy production and cell signaling are...
www.tandfonline.com
March 17, 2025 at 1:27 PM
Happy to share a large part of my PhD work that is now published in Autophagy!
www.tandfonline.com/doi/full/10....
www.tandfonline.com/doi/full/10....