Jess Ewald
@ewaldlab.org
Computational biologist using omics data (imaging, gene expression) to investigate the impacts of environmental contaminants on biological systems
Group Leader @EMBL-EBI (www.ewaldlab.org)
Group Leader @EMBL-EBI (www.ewaldlab.org)
It's been a great first few months at the EBI!
Meet our newest Research Group Leader: Jess Ewald @ewaldlab.org 🇨🇦
Jess’s group takes a multi-disciplinary approach to identify and characterise chemical hazards to humans and ecosystems, using cell profiling data, machine learning, and integrative data analysis.
www.ebi.ac.uk/about/news/p...
🖥️🧬
Jess’s group takes a multi-disciplinary approach to identify and characterise chemical hazards to humans and ecosystems, using cell profiling data, machine learning, and integrative data analysis.
www.ebi.ac.uk/about/news/p...
🖥️🧬
Welcome: Jess Ewald
Jess Ewald, Research Group Leader at EMBL-EBI, uses cell profiling and AI to find and characterise chemical hazards to humans and ecosysystems.
www.ebi.ac.uk
September 3, 2025 at 9:28 AM
It's been a great first few months at the EBI!
Reposted by Jess Ewald
Morph Map is now published in Nature Methods. Excited to see what the community discovers with this resource mapping ~15,000 human genes!
rdcu.be/ezGre
rdcu.be/ezGre
August 7, 2025 at 1:36 PM
Morph Map is now published in Nature Methods. Excited to see what the community discovers with this resource mapping ~15,000 human genes!
rdcu.be/ezGre
rdcu.be/ezGre
Check out this opportunity to join my lab as a postdoc! www.ebi.ac.uk/research/pos...
Every year, faculty from EMBL-EBI and the Wellcome Sanger Institute co-develop projects that allow fellows to be part of ✨both✨ of these amazing research institutes.
Every year, faculty from EMBL-EBI and the Wellcome Sanger Institute co-develop projects that allow fellows to be part of ✨both✨ of these amazing research institutes.
EMBL-EBI-Sanger postdoctoral fellowships (ESPOD)
The ESPOD fellowship builds on the collaborative relationship between EMBL-EBI and the Wellcome Sanger Institute, offering projects that combine experimental (wet-lab) and computational (dry-lab) appr...
www.ebi.ac.uk
August 7, 2025 at 9:14 AM
Check out this opportunity to join my lab as a postdoc! www.ebi.ac.uk/research/pos...
Every year, faculty from EMBL-EBI and the Wellcome Sanger Institute co-develop projects that allow fellows to be part of ✨both✨ of these amazing research institutes.
Every year, faculty from EMBL-EBI and the Wellcome Sanger Institute co-develop projects that allow fellows to be part of ✨both✨ of these amazing research institutes.
Two days left before the application closes!
🚨 We're hiring! 🚨 The Ewald Lab at EMBL-EBI is looking for a postdoctoral researcher in multi-omics, machine learning, and predictive toxicology to analyze a groundbreaking toxicology dataset as part of the OASIS Consortium.
More details & application here: lnkd.in/eHD7DMdX
More details & application here: lnkd.in/eHD7DMdX
March 31, 2025 at 1:49 PM
Two days left before the application closes!
Reposted by Jess Ewald
We're once again hiring a summer (+?) #bioimage #bioimageanalysis #software intern! Due to requirements of the funding program, you must be a current student, as well as work onsite in MA (+ have US work permission). Details at the link below. Spend your summer making great tools with fun people!
Software engineering intern - summer/fall 2025 - Cambridge, MA USA
If you are a current student (undergraduate/masters/PhD) with permission to work in the US and ability to work in-person in Cambridge, MA, US, consider a summer internship in the Broad Institute Imagi...
forum.image.sc
March 7, 2025 at 2:23 PM
We're once again hiring a summer (+?) #bioimage #bioimageanalysis #software intern! Due to requirements of the funding program, you must be a current student, as well as work onsite in MA (+ have US work permission). Details at the link below. Spend your summer making great tools with fun people!
🚨 We're hiring! 🚨 The Ewald Lab at EMBL-EBI is looking for a postdoctoral researcher in multi-omics, machine learning, and predictive toxicology to analyze a groundbreaking toxicology dataset as part of the OASIS Consortium.
More details & application here: lnkd.in/eHD7DMdX
More details & application here: lnkd.in/eHD7DMdX
March 5, 2025 at 5:31 PM
🚨 We're hiring! 🚨 The Ewald Lab at EMBL-EBI is looking for a postdoctoral researcher in multi-omics, machine learning, and predictive toxicology to analyze a groundbreaking toxicology dataset as part of the OASIS Consortium.
More details & application here: lnkd.in/eHD7DMdX
More details & application here: lnkd.in/eHD7DMdX
Reposted by Jess Ewald
We link molecular and functional phenotypes of islet cells from donors with type 1 diabetes to understand impaired insulin and glucagon secretion. Immune signalling, nuclear exclusion, mTOR and lysosomes in alpha cell dysfunction.
https://www.biorxiv.org/content/10.1101/2025.02.20.639325v1
https://www.biorxiv.org/content/10.1101/2025.02.20.639325v1
February 21, 2025 at 12:40 PM
We link molecular and functional phenotypes of islet cells from donors with type 1 diabetes to understand impaired insulin and glucagon secretion. Immune signalling, nuclear exclusion, mTOR and lysosomes in alpha cell dysfunction.
https://www.biorxiv.org/content/10.1101/2025.02.20.639325v1
https://www.biorxiv.org/content/10.1101/2025.02.20.639325v1
First large-scale analysis of chemical toxicity in primary human hepatocytes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes
High-throughput, human-relevant approaches for predicting chemical toxicity are urgently needed for better decision-making in human health. Here, we apply image-based profiling (the Cell Painting assa...
www.biorxiv.org
February 3, 2025 at 12:32 PM
First large-scale analysis of chemical toxicity in primary human hepatocytes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Jess Ewald
We've a postdoc opening for our lab at the Broad: Cambridge MA!
Must have experience in toxicology + data science
Work on the wonderful OASIS dataset we are producing... Cell Painting, transcriptomics, proteomics in various liver cell and tissue models!
broad.io/mlcbpostdoc
Must have experience in toxicology + data science
Work on the wonderful OASIS dataset we are producing... Cell Painting, transcriptomics, proteomics in various liver cell and tissue models!
broad.io/mlcbpostdoc
December 18, 2024 at 3:50 PM
We've a postdoc opening for our lab at the Broad: Cambridge MA!
Must have experience in toxicology + data science
Work on the wonderful OASIS dataset we are producing... Cell Painting, transcriptomics, proteomics in various liver cell and tissue models!
broad.io/mlcbpostdoc
Must have experience in toxicology + data science
Work on the wonderful OASIS dataset we are producing... Cell Painting, transcriptomics, proteomics in various liver cell and tissue models!
broad.io/mlcbpostdoc
Reposted by Jess Ewald
New Year, new job? Delighted to announce two early-career-level (post-BA/BS or MA) positions in my lab, and an open call for computational postdocs at the Broad!
First, an image analysis associate - work on high content screens for all kinds of cells and dimensionalities! See more at link (1/4)
First, an image analysis associate - work on high content screens for all kinds of cells and dimensionalities! See more at link (1/4)
Image analysis associate job description
Image Analysis Associate Broad Institute of MIT and Harvard, Cambridge, MA Impact the discovery of new disease therapies in the Cimini laboratory at the Imaging Platform Join our vibrant, world-clas...
docs.google.com
December 16, 2024 at 3:20 PM
New Year, new job? Delighted to announce two early-career-level (post-BA/BS or MA) positions in my lab, and an open call for computational postdocs at the Broad!
First, an image analysis associate - work on high content screens for all kinds of cells and dimensionalities! See more at link (1/4)
First, an image analysis associate - work on high content screens for all kinds of cells and dimensionalities! See more at link (1/4)
🎉 I'm starting my own lab at EMBL-EBI (Cambridge, UK; June 2025) 🎉
We will focus on identifying and characterizing chemical hazards to humans and ecosystems using computational biology methods.
I am beginning the search for two postdocs now - stay tuned for more details!
ewaldlab.org
We will focus on identifying and characterizing chemical hazards to humans and ecosystems using computational biology methods.
I am beginning the search for two postdocs now - stay tuned for more details!
ewaldlab.org
Ewald Lab
@ EMBL-EBI. We identify and characterize chemical hazards to both humans and ecosystems with cell profiling data, machine learning, and integrative data analysis.
ewaldlab.org
December 13, 2024 at 2:12 PM
🎉 I'm starting my own lab at EMBL-EBI (Cambridge, UK; June 2025) 🎉
We will focus on identifying and characterizing chemical hazards to humans and ecosystems using computational biology methods.
I am beginning the search for two postdocs now - stay tuned for more details!
ewaldlab.org
We will focus on identifying and characterizing chemical hazards to humans and ecosystems using computational biology methods.
I am beginning the search for two postdocs now - stay tuned for more details!
ewaldlab.org
Reposted by Jess Ewald
Excited to present our spotlight paper at #NeurIPS!
MOTIVE is a new dataset + benchmark for predicting drug-target interactions, using Cell Painting data
Location: Fri 13 Dec 4:30 p.m. PST @ East Exhibit Hall A-C #4208
Poster: neurips.cc/virtual/2024...
Paper: arxiv.org/abs/2406.08649
MOTIVE is a new dataset + benchmark for predicting drug-target interactions, using Cell Painting data
Location: Fri 13 Dec 4:30 p.m. PST @ East Exhibit Hall A-C #4208
Poster: neurips.cc/virtual/2024...
Paper: arxiv.org/abs/2406.08649
December 13, 2024 at 12:39 PM
Excited to present our spotlight paper at #NeurIPS!
MOTIVE is a new dataset + benchmark for predicting drug-target interactions, using Cell Painting data
Location: Fri 13 Dec 4:30 p.m. PST @ East Exhibit Hall A-C #4208
Poster: neurips.cc/virtual/2024...
Paper: arxiv.org/abs/2406.08649
MOTIVE is a new dataset + benchmark for predicting drug-target interactions, using Cell Painting data
Location: Fri 13 Dec 4:30 p.m. PST @ East Exhibit Hall A-C #4208
Poster: neurips.cc/virtual/2024...
Paper: arxiv.org/abs/2406.08649
A new paper from the Carpenter-Singh Lab - such a cool project and I'm really excited about the possibilities that these data will unlock for future projects!
Now on biorxiv! The JUMP-Cell Painting Consortium’s paper:
“Morphological map of under- and over-expression of genes in human cells”
This is the genetic perturbation portion of the JUMP’s dataset; our chemical perturbation paper will come in a few months
www.biorxiv.org/content/10.1...
“Morphological map of under- and over-expression of genes in human cells”
This is the genetic perturbation portion of the JUMP’s dataset; our chemical perturbation paper will come in a few months
www.biorxiv.org/content/10.1...
Morphological map of under- and over-expression of genes in human cells
Cell Painting images offer valuable insights into the state of a cell and enable many biological applications, but publicly available arrayed datasets only include hundreds of genes perturbed. The JUM...
www.biorxiv.org
December 4, 2024 at 2:21 PM
A new paper from the Carpenter-Singh Lab - such a cool project and I'm really excited about the possibilities that these data will unlock for future projects!
Really loved the concept of distinguishing between 'fun challenge stress' and 'threat stress' on this Ologies podcast on burnout: open.spotify.com/episode/0ccV...
Reflecting on my own work patterns as I mentally prepare to start my own lab.
Any tips out there?
Reflecting on my own work patterns as I mentally prepare to start my own lab.
Any tips out there?
Ergopathology (BURNOUT) with Kandi Wiens
Ologies with Alie Ward · Episode
open.spotify.com
November 16, 2024 at 3:11 PM
Really loved the concept of distinguishing between 'fun challenge stress' and 'threat stress' on this Ologies podcast on burnout: open.spotify.com/episode/0ccV...
Reflecting on my own work patterns as I mentally prepare to start my own lab.
Any tips out there?
Reflecting on my own work patterns as I mentally prepare to start my own lab.
Any tips out there?
Reposted by Jess Ewald
The 2024 biennial survey by COBA, @bioimagingna.bsky.social, @royalmicrosoc.bsky.social and @globias.bsky.social is here to connect imaging users with image analysis. Check this out @biologists.bsky.social for more details - focalplane.biologists.com/2024/11/13/b...
Bridging Imaging Users to Imaging Analysis - 2024 - FocalPlane
Bridging Imaging Users to Imaging Analysis - 2024 -
focalplane.biologists.com
November 15, 2024 at 6:55 PM
The 2024 biennial survey by COBA, @bioimagingna.bsky.social, @royalmicrosoc.bsky.social and @globias.bsky.social is here to connect imaging users with image analysis. Check this out @biologists.bsky.social for more details - focalplane.biologists.com/2024/11/13/b...