Philipp Altrock
@evolsci.bsky.social
dynamics of cancer by means of ecology & evolution, and modeling & simulation. views my own. https://paltrock.github.io/
Reposted by Philipp Altrock
🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
September 17, 2025 at 1:10 PM
🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
Reposted by Philipp Altrock
"increasing reports of AI hallucinations making their way into academic papers, court decisions, and White House reports [that] have been caught by humans; One wonders how many haven’t been identified and are being spread across the information ecosystem" www.science.org/doi/10.1126/...
Why AI chatbots lie to us
A few weeks ago, a colleague of mine needed to collect and format some data from a website, and he asked the latest version of Anthropic’s generative AI system, Claude, for help. Claude cheerfully agr...
www.science.org
July 25, 2025 at 6:38 PM
"increasing reports of AI hallucinations making their way into academic papers, court decisions, and White House reports [that] have been caught by humans; One wonders how many haven’t been identified and are being spread across the information ecosystem" www.science.org/doi/10.1126/...
Reposted by Philipp Altrock
I wrote a new piece on how much progress has been made in treating childhood leukemia.
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
June 9, 2025 at 7:43 AM
I wrote a new piece on how much progress has been made in treating childhood leukemia.
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
Reposted by Philipp Altrock
The astounding contribution of US academic science to new medicines
www.statnews.com/2025/06/06/u...
www.statnews.com/2025/06/06/u...
We set out to quantify U.S. academic contributions to medicines. The results stunned even us
From 2020 to 2024, universities contributed patents underpinning 50% of FDA-approved drugs. 87% of those academic breakthroughs came from American institutions.
www.statnews.com
June 7, 2025 at 6:04 PM
The astounding contribution of US academic science to new medicines
www.statnews.com/2025/06/06/u...
www.statnews.com/2025/06/06/u...
Reposted by Philipp Altrock
A great blog post (3rd in the series!) from the BIRS meeting in Canada. This time by @evolsci.bsky.social @glorenzogz.bsky.social @rrockne.bsky.social amongst others
Biophysically-Constrained GBM Predictions via Deep-Learning Integrating Structural SINDY with Mechanistic Filters
Biophysically-Constrained GBM Predictions via Deep-Learning Integrating Structural SINDY with Mechanistic Filters
BIRS Recap: Biophysically-Constrained GBM Predictions via Deep-Learning Integrating Structural SINDY with Mechanistic Filters
mathematical-oncology.org
mathematical-oncology.org
May 19, 2025 at 6:51 PM
A great blog post (3rd in the series!) from the BIRS meeting in Canada. This time by @evolsci.bsky.social @glorenzogz.bsky.social @rrockne.bsky.social amongst others
Biophysically-Constrained GBM Predictions via Deep-Learning Integrating Structural SINDY with Mechanistic Filters
Biophysically-Constrained GBM Predictions via Deep-Learning Integrating Structural SINDY with Mechanistic Filters
Reposted by Philipp Altrock
New post on shallowness of Deep Research AI tools, and solutions that don’t really solve the problems we often face as scientists: kucharski.substack.com/p/the-shallo...
March 3, 2025 at 11:45 AM
New post on shallowness of Deep Research AI tools, and solutions that don’t really solve the problems we often face as scientists: kucharski.substack.com/p/the-shallo...
Reposted by Philipp Altrock
Silence will not shield scientists from the consequences of an increasingly hostile political landscape.
UK and other non-US scientists must act to support our US colleagues.
Here's what I think we should be doing...
🧵
1/35
UK and other non-US scientists must act to support our US colleagues.
Here's what I think we should be doing...
🧵
1/35
February 21, 2025 at 11:57 AM
Silence will not shield scientists from the consequences of an increasingly hostile political landscape.
UK and other non-US scientists must act to support our US colleagues.
Here's what I think we should be doing...
🧵
1/35
UK and other non-US scientists must act to support our US colleagues.
Here's what I think we should be doing...
🧵
1/35
Reposted by Philipp Altrock
Please don’t stop sharing and posting your science because of the current attack on it, it is still valuable and reminds us what the fight is for
February 17, 2025 at 11:50 PM
Please don’t stop sharing and posting your science because of the current attack on it, it is still valuable and reminds us what the fight is for
Reposted by Philipp Altrock
#medsky#pedsky#idsky#immunosky 🧪
In the midst of all of the scary headlines recently, I thought I could take a moment to share a bit of good news: for the first time in history, a malaria vaccine with >90% efficacy seems to be within reach!
Here’s why that’s a really big deal for EVERYONE 🧵
In the midst of all of the scary headlines recently, I thought I could take a moment to share a bit of good news: for the first time in history, a malaria vaccine with >90% efficacy seems to be within reach!
Here’s why that’s a really big deal for EVERYONE 🧵
A Single-Dose Breakthrough: PfSPZ-LARC Vaccines Offer Transformative Protection Against Malaria – Sanaria
sanaria.com
February 13, 2025 at 1:23 PM
#medsky#pedsky#idsky#immunosky 🧪
In the midst of all of the scary headlines recently, I thought I could take a moment to share a bit of good news: for the first time in history, a malaria vaccine with >90% efficacy seems to be within reach!
Here’s why that’s a really big deal for EVERYONE 🧵
In the midst of all of the scary headlines recently, I thought I could take a moment to share a bit of good news: for the first time in history, a malaria vaccine with >90% efficacy seems to be within reach!
Here’s why that’s a really big deal for EVERYONE 🧵
Reposted by Philipp Altrock
Stephen J Gould (1985) talked about the "tiers of time" with macroevolutionary dynamics distinct from short-time microevolution.
But did you know that macroevolution itself shows qualitatively different dynamics at different time scales?
www.nature.com/articles/s41...
🧪 #EvoBio #Paleobio ⚒️ #Geology
But did you know that macroevolution itself shows qualitatively different dynamics at different time scales?
www.nature.com/articles/s41...
🧪 #EvoBio #Paleobio ⚒️ #Geology
January 13, 2025 at 11:00 PM
Stephen J Gould (1985) talked about the "tiers of time" with macroevolutionary dynamics distinct from short-time microevolution.
But did you know that macroevolution itself shows qualitatively different dynamics at different time scales?
www.nature.com/articles/s41...
🧪 #EvoBio #Paleobio ⚒️ #Geology
But did you know that macroevolution itself shows qualitatively different dynamics at different time scales?
www.nature.com/articles/s41...
🧪 #EvoBio #Paleobio ⚒️ #Geology
Reposted by Philipp Altrock
🚨 Annual IMPRS Call for Doctoral Positions at MPI-EvolBio 🚨
🎓 Fully-funded 3.5-year doctoral projects available in diverse research areas!
#PhD #ResearchOpportunities #IMPRS #Science evolbio.mpg.de/3801127/annu...
🎓 Fully-funded 3.5-year doctoral projects available in diverse research areas!
#PhD #ResearchOpportunities #IMPRS #Science evolbio.mpg.de/3801127/annu...
January 10, 2025 at 2:17 PM
🚨 Annual IMPRS Call for Doctoral Positions at MPI-EvolBio 🚨
🎓 Fully-funded 3.5-year doctoral projects available in diverse research areas!
#PhD #ResearchOpportunities #IMPRS #Science evolbio.mpg.de/3801127/annu...
🎓 Fully-funded 3.5-year doctoral projects available in diverse research areas!
#PhD #ResearchOpportunities #IMPRS #Science evolbio.mpg.de/3801127/annu...
Reposted by Philipp Altrock
We invite you to the “Cell Plasticity in Cancer Evolution” workshop at the MPI Evolutionary Biology, May 19–22, 2025! Join international experts who will share insights on cell plasticity in cancer and the latest research and therapies.
Registration: workshops.evolbio.mpg.de/event/123/ov...
Registration: workshops.evolbio.mpg.de/event/123/ov...
Cell Plasticity in Cancer Evolution
workshops.evolbio.mpg.de
November 14, 2024 at 1:39 PM
We invite you to the “Cell Plasticity in Cancer Evolution” workshop at the MPI Evolutionary Biology, May 19–22, 2025! Join international experts who will share insights on cell plasticity in cancer and the latest research and therapies.
Registration: workshops.evolbio.mpg.de/event/123/ov...
Registration: workshops.evolbio.mpg.de/event/123/ov...
Reposted by Philipp Altrock
ABC, NBC & CBS dedicated about 16 minutes of airtime last night to the California wildfires without once mentioning climate change.
Since the news failed do it's job, here's a short summary of the role of climate change and wildfire risk:
www.noaa.gov/noaa-wildfir...
Since the news failed do it's job, here's a short summary of the role of climate change and wildfire risk:
www.noaa.gov/noaa-wildfir...
Wildfire climate connection
Climate change, including increased heat, extended drought, and a thirsty atmosphere, has been a key driver in increasing the risk and extent of wildfires in the western United States during the last ...
www.noaa.gov
January 8, 2025 at 8:03 PM
ABC, NBC & CBS dedicated about 16 minutes of airtime last night to the California wildfires without once mentioning climate change.
Since the news failed do it's job, here's a short summary of the role of climate change and wildfire risk:
www.noaa.gov/noaa-wildfir...
Since the news failed do it's job, here's a short summary of the role of climate change and wildfire risk:
www.noaa.gov/noaa-wildfir...
Reposted by Philipp Altrock
New #BulletinMathBio paper by Qianci Yang, Arne Traulsen, and @evolsci.bsky.social on Integration of Immune Cell-Target Cell Conjugate Dynamics Changes the Time Scale of Immune Control of Cancer.
link.springer.com/article/10.1...
🧪
link.springer.com/article/10.1...
🧪
Integration of Immune Cell-Target Cell Conjugate Dynamics Changes the Time Scale of Immune Control of Cancer - Bulletin of Mathematical Biology
The human immune system can recognize, attack, and eliminate cancer cells, but cancers can escape this immune surveillance. Variants of ecological predator–prey models can capture the dynamics of such...
link.springer.com
January 4, 2025 at 2:10 AM
New #BulletinMathBio paper by Qianci Yang, Arne Traulsen, and @evolsci.bsky.social on Integration of Immune Cell-Target Cell Conjugate Dynamics Changes the Time Scale of Immune Control of Cancer.
link.springer.com/article/10.1...
🧪
link.springer.com/article/10.1...
🧪
Reposted by Philipp Altrock
Staggering statistics at #ASH24 #TreatingFairly
Patients with cancer who go bankrupt are nearly 80% more likely to die regardless of disease status.
Our system quite literally kills people.
Patients with cancer who go bankrupt are nearly 80% more likely to die regardless of disease status.
Our system quite literally kills people.
December 8, 2024 at 12:17 AM
Staggering statistics at #ASH24 #TreatingFairly
Patients with cancer who go bankrupt are nearly 80% more likely to die regardless of disease status.
Our system quite literally kills people.
Patients with cancer who go bankrupt are nearly 80% more likely to die regardless of disease status.
Our system quite literally kills people.
Reposted by Philipp Altrock
The deep goal of bluesky is to decentralize the social internet so that every individual controls their experience of it rather than having it be controlled by 5 random billionaires. Everyone thinks they signed up for a demuskified twitter...we actually signed an exciting and bizarre experiment.
December 3, 2024 at 4:05 PM
The deep goal of bluesky is to decentralize the social internet so that every individual controls their experience of it rather than having it be controlled by 5 random billionaires. Everyone thinks they signed up for a demuskified twitter...we actually signed an exciting and bizarre experiment.
Reposted by Philipp Altrock
It uses C++ under the hood for the heavy lifting, making it quite fast.
This version includes new features, bug fixes, and improved documentation: graph-tool.skewed.de/static/doc/
Did you know that you can infer network from dynamics using graph-tool? graph-tool.skewed.de/static/doc/d... 2/N
This version includes new features, bug fixes, and improved documentation: graph-tool.skewed.de/static/doc/
Did you know that you can infer network from dynamics using graph-tool? graph-tool.skewed.de/static/doc/d... 2/N
December 2, 2024 at 12:55 PM
It uses C++ under the hood for the heavy lifting, making it quite fast.
This version includes new features, bug fixes, and improved documentation: graph-tool.skewed.de/static/doc/
Did you know that you can infer network from dynamics using graph-tool? graph-tool.skewed.de/static/doc/d... 2/N
This version includes new features, bug fixes, and improved documentation: graph-tool.skewed.de/static/doc/
Did you know that you can infer network from dynamics using graph-tool? graph-tool.skewed.de/static/doc/d... 2/N
Reposted by Philipp Altrock
If you are attending @evomg-bcn.bsky.social or are at the @crg.eu or in Barcelona I’ll be giving the closing keynote at 11:30am on some of our on going @evoltherapy.bsky.social clinical trials as well as showing how we use @mathonco.bsky.social to drive translation.
November 22, 2024 at 10:05 AM
If you are attending @evomg-bcn.bsky.social or are at the @crg.eu or in Barcelona I’ll be giving the closing keynote at 11:30am on some of our on going @evoltherapy.bsky.social clinical trials as well as showing how we use @mathonco.bsky.social to drive translation.
Reposted by Philipp Altrock
Pls share 🌟Join the IMP as a Group Leader
We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social
👉https://tinyurl.com/impgl2025
November 20, 2024 at 10:46 AM
Pls share 🌟Join the IMP as a Group Leader
We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social
👉https://tinyurl.com/impgl2025
Reposted by Philipp Altrock
For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):
thisweekmathonco.substack.com
thisweekmathonco.substack.com
This week in Mathematical Oncology | Jeffrey West | Substack
"This week in Mathematical Oncology" -- the weekly email newsletter. Click to read This week in Mathematical Oncology, by Jeffrey West, a Substack publication with thousands of subscribers.
thisweekmathonco.substack.com
November 17, 2024 at 4:50 PM
For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):
thisweekmathonco.substack.com
thisweekmathonco.substack.com
Reposted by Philipp Altrock
As a computational social scientist I could not miss to follow this beautiful creature: the BlueSky social network during its growth in the last hours!
In this video I show just a snapshot for about 210k users and their 500k-ish connections #academicsky
Zoom in the next post
youtu.be/JcmYZtWGnjQ
In this video I show just a snapshot for about 210k users and their 500k-ish connections #academicsky
Zoom in the next post
youtu.be/JcmYZtWGnjQ
The “great Xodus” and the growth of BlueSky
YouTube video by Manlio De Domenico
youtu.be
November 15, 2024 at 9:24 AM
As a computational social scientist I could not miss to follow this beautiful creature: the BlueSky social network during its growth in the last hours!
In this video I show just a snapshot for about 210k users and their 500k-ish connections #academicsky
Zoom in the next post
youtu.be/JcmYZtWGnjQ
In this video I show just a snapshot for about 210k users and their 500k-ish connections #academicsky
Zoom in the next post
youtu.be/JcmYZtWGnjQ
Reposted by Philipp Altrock
1/3 🌍 We're hiring! The Medical Systems Biology Lab at Kiel University is looking for a passionate #PostDoc in #Metabolic #Microbiome #Modeling. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science! @kieluni @UKSH_KI_HL
🔗 jobs.uksh.de/job/Kiel-Pos...
🔗 jobs.uksh.de/job/Kiel-Pos...
November 15, 2024 at 9:24 AM
1/3 🌍 We're hiring! The Medical Systems Biology Lab at Kiel University is looking for a passionate #PostDoc in #Metabolic #Microbiome #Modeling. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science! @kieluni @UKSH_KI_HL
🔗 jobs.uksh.de/job/Kiel-Pos...
🔗 jobs.uksh.de/job/Kiel-Pos...