estella newcombe
@estellaan.bsky.social
existing somewhere between neuroscience and biochemistry
australian in copenhagen
australian in copenhagen
Huge congratulations to Ed and co on this! Once you are a part of the HD research community you never really leave and this news is just so amazing 🥲
September 25, 2025 at 7:11 AM
Huge congratulations to Ed and co on this! Once you are a part of the HD research community you never really leave and this news is just so amazing 🥲
I’ll always be an acdc hater #aushottest100
July 26, 2025 at 8:38 AM
I’ll always be an acdc hater #aushottest100
Blasting the Triple J Hottest 100 Australian songs for my Danish neighbours at 10am so they can learn more about their queens culture 😌 #aushottest100
July 26, 2025 at 8:29 AM
Blasting the Triple J Hottest 100 Australian songs for my Danish neighbours at 10am so they can learn more about their queens culture 😌 #aushottest100
Reposted by estella newcombe
Major U.S. health agencies, including the NIH and the CDC, are firing thousands of probationary employees this afternoon.
Follow Science’s coverage of President Donald Trump’s impact on U.S. research and science globally. ⬇️ scim.ag/40XtSSi
Follow Science’s coverage of President Donald Trump’s impact on U.S. research and science globally. ⬇️ scim.ag/40XtSSi
Welcome to Trump Tracker: Probationary workers at health agencies being fired today
Follow President Donald Trump’s impact on U.S. research and science globally
scim.ag
February 14, 2025 at 6:34 PM
Major U.S. health agencies, including the NIH and the CDC, are firing thousands of probationary employees this afternoon.
Follow Science’s coverage of President Donald Trump’s impact on U.S. research and science globally. ⬇️ scim.ag/40XtSSi
Follow Science’s coverage of President Donald Trump’s impact on U.S. research and science globally. ⬇️ scim.ag/40XtSSi
Truly a Berlin snowman
February 14, 2025 at 9:57 AM
Truly a Berlin snowman
I think my main marketable skill is being able to tell whether Trent Reznor made the soundtrack without having to look it up
January 30, 2025 at 12:27 PM
I think my main marketable skill is being able to tell whether Trent Reznor made the soundtrack without having to look it up
Smarter Copenhagen commuters chose to wfh today
January 3, 2025 at 7:18 AM
Smarter Copenhagen commuters chose to wfh today
A nice write up on the paper and our findings in Chemistry World, thank you @gomobel.bsky.social!
Debunked dogma: disordered proteins disregard ligands’ chirality 🧬 my latest story for @chemistryworld.bsky.social on a fantastic and surprising Nature paper by Johan Olsen and Birthe Kragelund teams 🇩🇰 Read more below! #realtimechem #chemsky 🧪 www.chemistryworld.com/news/debunke...
Debunked dogma: disordered proteins disregard ligands’ chirality
Understanding unfolded proteins could boost drug discovery and decipher origins of life mysteries
www.chemistryworld.com
December 18, 2024 at 6:49 PM
A nice write up on the paper and our findings in Chemistry World, thank you @gomobel.bsky.social!
So excited that the work on protein chirality and the origins of life on this planet will continue with this grant awarded to @bbkrage.bsky.social - huge news! Stort tillykke!!! www.carlsbergfondet.dk/det-har-vi-s...
Protein Chirality and the Origin of Life | Carlsbergfondet.dk
www.carlsbergfondet.dk
December 17, 2024 at 12:13 PM
So excited that the work on protein chirality and the origins of life on this planet will continue with this grant awarded to @bbkrage.bsky.social - huge news! Stort tillykke!!! www.carlsbergfondet.dk/det-har-vi-s...
Thanks for the write up Derek!
A look at just how disordered a disordered protein-protein pair can get. Do they even care about stereochemistry any more?
Now That's What I Call Disordered
www.science.org
December 5, 2024 at 2:13 PM
Thanks for the write up Derek!
We did this crazy project where we tried to see if proteins could interact with their mirror image ligand. Seems impossible when proteins need to form 3D structures to interact. But what about if the interaction remains disordered???
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Stereochemistry in the disorder–order continuum of protein interactions - Nature
Studies on protein–protein interactions using proteins containing d- or l-amino acids show that stereoselectivity of binding varies with the degree of disorder within the complex.
www.nature.com
November 27, 2024 at 8:31 PM
We did this crazy project where we tried to see if proteins could interact with their mirror image ligand. Seems impossible when proteins need to form 3D structures to interact. But what about if the interaction remains disordered???
www.nature.com/articles/s41...
www.nature.com/articles/s41...
More followers on here in the last week than the last 6 months, I wonder what could have changed 😅😬
November 17, 2024 at 4:40 PM
More followers on here in the last week than the last 6 months, I wonder what could have changed 😅😬
Reposted by estella newcombe
A labor of love - our review on why IDRs matter for cellular function is live in Nat. Rev. Mol. Cell. Biol:
www.nature.com/articles/s41...
Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!
www.nature.com/articles/s41...
Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!
November 13, 2023 at 2:56 PM
A labor of love - our review on why IDRs matter for cellular function is live in Nat. Rev. Mol. Cell. Biol:
www.nature.com/articles/s41...
Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!
www.nature.com/articles/s41...
Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!
Feeling vulnerable (writing a research proposal)
November 5, 2023 at 9:36 PM
Feeling vulnerable (writing a research proposal)
i research neurodegenerative proteins (& other idps!) & how their interactions lead to pathology. have bounced between huntington's, alzheimer's & parkinson's, & from structural biology to mouse models & human tissues, so v much a jack-of-all-trades when it comes to neurodegenerative diseases
September 19, 2023 at 2:16 PM
i research neurodegenerative proteins (& other idps!) & how their interactions lead to pathology. have bounced between huntington's, alzheimer's & parkinson's, & from structural biology to mouse models & human tissues, so v much a jack-of-all-trades when it comes to neurodegenerative diseases
migrating to a new platform feels harder than moving internationally in my 30s honestly
September 19, 2023 at 2:12 PM
migrating to a new platform feels harder than moving internationally in my 30s honestly