Emma Houlder
emmahoulder.bsky.social
Emma Houlder
@emmahoulder.bsky.social
Researcher at LUMC.
Immunology, schistosomiasis, vaccines.
In schistosome 🪱-endemic areas, people are repeatedly reinfected — but we still don’t fully understand how T cell responses develop in these cycles.

In my first ever last-author paper (😱) we investigate this, comparing endemic and repeat controlled human schistosome infection: rdcu.be/exH58
T cell responses in repeated controlled human schistosome infection compared to natural exposure
Nature Communications - In schistosomiasis-endemic regions, the cyclical nature of infection and treatment complicates understanding of host immune responses. Repeated controlled human Schistosoma...
rdcu.be
July 31, 2025 at 3:15 PM
[1/7]
How close are we to a schistosomiasis vaccine?
With help from an #MSCA fellowship and support from Batavia Biosciences, I spent 6 months reviewing 100+ pre-clinical studies on S. mansoni vaccines.
Here's what we found:
📄 doi.org/10.1371/jour...
Pre-clinical studies of Schistosoma mansoni vaccines: A scoping review
Author summary Schistosomiasis, a major neglected tropical disease, is caused by infection with parasitic worms of the Schistosoma species, including Schistosoma mansoni. Individuals can be repeatedly...
doi.org
June 12, 2025 at 2:42 PM
FIRST POST!
Fungi drive asthma, but does this require germination?

We show A. fumigatus spores activate DCs after 3hrs of swelling, promoting airway allergy. Antifungal itraconazole limits swelling & reduces allergic inflammation.
Check it out: doi.org/10.1016/j.ja...
@drpetercook.bsky.social 👩‍🔬
December 20, 2024 at 10:39 AM
Reposted by Emma Houlder
First 🦋 post (great to join everyone here) about our paper that's been published in JACI: www.jacionline.org/article/S009...

Check it out if you have ever wondered how fungal spore growth controls how dendritic cells (clearly THE best immune cell) trigger inflammation that causes asthma...
DEFINE_ME
www.jacionline.org
November 25, 2024 at 1:35 PM