Emily Park
@emilypark.bsky.social
MD/PhD student at Baylor College of Medicine. Currently a PhD candidate in the Di Stefano lab studying gene reg in human stem cells. Fan of puzzles, music, novels, naps.
Check out the latest work from the lab published today!
1/ Excited to share our new study with @brumbaugh-lab.bsky.social, out in @natbiotech.nature.com! P-bodies selectively sequester RNAs encoding cell fate regulators, often from the preceding developmental stage. Releasing these RNAs can drive changes in cell identity. 🧵 www.nature.com/articles/s41...
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology
Stem cell differentiation is controlled by manipulating RNA condensates.
www.nature.com
October 28, 2025 at 5:03 PM
Check out the latest work from the lab published today!
Reposted by Emily Park
New preprint from the lab! With @brumbaugh-lab.bsky.social , we show that P-bodies sequester developmentally relevant RNAs to influence cell fate. miRNAs direct this conserved regulatory process, and manipulating it enhances totipotency and germ cell programming. www.biorxiv.org/content/10.1...
Selective RNA sequestration in biomolecular condensates directs cell fate transitions
Recent studies have emphasized the significance of biomolecular condensates in modulating gene expression through RNA processing and translational control. However, the functional roles of RNA condens...
www.biorxiv.org
May 12, 2025 at 1:44 PM
New preprint from the lab! With @brumbaugh-lab.bsky.social , we show that P-bodies sequester developmentally relevant RNAs to influence cell fate. miRNAs direct this conserved regulatory process, and manipulating it enhances totipotency and germ cell programming. www.biorxiv.org/content/10.1...
Reposted by Emily Park
Happy to say our paper with the Whipple lab on snoRNA target profiling with chimeric eCLIP is now out! Great work by co-first authors Joey & Min with the help of a bunch of other folks!
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
Mapping snoRNA-target RNA interactions in an RNA-binding protein-dependent manner with chimeric eCLIP - Genome Biology
Background Small nucleolar RNAs (snoRNAs) are non-coding RNAs that function in ribosome and spliceosome biogenesis, primarily by guiding modifying enzymes to specific sites on ribosomal RNA (rRNA) and...
genomebiology.biomedcentral.com
February 25, 2025 at 6:17 PM
Happy to say our paper with the Whipple lab on snoRNA target profiling with chimeric eCLIP is now out! Great work by co-first authors Joey & Min with the help of a bunch of other folks!
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
Check out the latest review from the Di Stefano lab! For anyone interested in condensates in gene reg and their implications for immunology/cancer.
1/ Pleased to share our review, published today
@natrevimmunol.bsky.social, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. www.nature.com/articles/s41...
@natrevimmunol.bsky.social, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. www.nature.com/articles/s41...
Biomolecular condensates in immune cell fate - Nature Reviews Immunology
Recent studies suggest that biomolecular condensates — membrane-less assemblies of proteins and nucleic acids — are involved in regulating gene expression to ensure proper immune cell development. Thi...
www.nature.com
January 28, 2025 at 4:49 PM
Check out the latest review from the Di Stefano lab! For anyone interested in condensates in gene reg and their implications for immunology/cancer.
Reposted by Emily Park
Excited to share my first manuscript in the @distefanolab.bsky.social , now out in @emboreports.bsky.social! 🎉 We demonstrate how two transposable elements, MER51B and LTR5_Hs, serve as selective indicators of human pluripotency states embopress.org/doi/full/10..... 🧵 below:
Transposable element activity captures human pluripotent cell states | EMBO reports
imageimageA novel dual reporter system based on transposable elements LTR5_Hs and MER51B enables
precise tracking of human pluripotent stem cell states. This system reveals also a
rare, metastable pri...
www.embopress.org
December 13, 2024 at 8:20 PM
Excited to share my first manuscript in the @distefanolab.bsky.social , now out in @emboreports.bsky.social! 🎉 We demonstrate how two transposable elements, MER51B and LTR5_Hs, serve as selective indicators of human pluripotency states embopress.org/doi/full/10..... 🧵 below:
The latest paper from the Di Stefano lab showing the power of using transposable elements as reporters of different human pluripotent states! www.embopress.org/doi/full/10....
Transposable element activity captures human pluripotent cell states | EMBO reports
imageimageA novel dual reporter system based on transposable elements LTR5_Hs and MER51B enables
precise tracking of human pluripotent stem cell states. This system reveals also a
rare, metastable pri...
www.embopress.org
December 12, 2024 at 11:44 PM
The latest paper from the Di Stefano lab showing the power of using transposable elements as reporters of different human pluripotent states! www.embopress.org/doi/full/10....
Reposted by Emily Park
Happy to have the Srinivas lab on Bluesky!
Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...
Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...
November 18, 2024 at 4:44 PM
Happy to have the Srinivas lab on Bluesky!
Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...
Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...