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The SEP article on scientific reductionism notes that the etymology of the word "reduction" is "to bring back" something to something else. So in a methodological sense, reduction is bringing one theory or ontology back to a simpler or more fundamental theory or ontology. The Wikipedia entry on reductionism identifies different kinds: ontological, methodological, and theory reductionism. I think the ontological one is the most interesting here, the proposition that all of reality consists of a small number of building blocks.