Elise Dalmas
edal84.bsky.social
Elise Dalmas
@edal84.bsky.social
Immunoregulation of pancreatic islets, physiology and diabetes, macrophage enthousiast ! @INEM INSERM, Paris
Reposted by Elise Dalmas
Macrophage-toxic bacteria from patients with ulcerative colitis worsen gut inflammation in mice @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
November 21, 2025 at 2:11 AM
Reposted by Elise Dalmas
A new #ScienceImmunology study finds that mice and humans have pancreatic islet-resident macrophages with elevated antioxidant profiles, which could shield β cells from oxidative stress. https://scim.ag/49cqs3M
An islet-resident macrophage antioxidant program preserves β cell physiology
SLC7A11 licenses metabolic and antioxidant activities in islet macrophages, supporting β cell insulin secretion and redox homeostasis.
scim.ag
November 18, 2025 at 4:00 PM
Very excited to share that our paper on pancreatic islet-resident macrophages is out ! Grateful to contribute to our understanding of these fascinating cells - special thanks to all of our collaborators ! #worlddiabetesday www.science.org/doi/10.1126/...
An islet-resident macrophage antioxidant program preserves β cell physiology
SLC7A11 licenses metabolic and antioxidant activities in islet macrophages, supporting β cell insulin secretion and redox homeostasis.
www.science.org
November 14, 2025 at 10:03 PM
Reposted by Elise Dalmas
Excited to share my latest postdoc work on systemic metabolic homeostasis! We show that nutrient consumption fluxes compete, and this competitive catabolism helps explain why obesity drives diabetes. Explore the model with our interactive web app: compcat.princeton.edu

doi.org/10.1101/2025...
October 31, 2025 at 1:19 PM
Reposted by Elise Dalmas
Nature research paper: Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death

go.nature.com/476WZqg
Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death - Nature
Enrichment for efferocytic macrophages in the islets of Langerhans promotes the accumulation of anergic-like CD4+ T cells and dampens autoimmune diabetes.
go.nature.com
October 2, 2025 at 2:26 PM