Dong-Jiunn Jeffery Truong
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earthnut89.bsky.social
Dong-Jiunn Jeffery Truong
@earthnut89.bsky.social
Passionate molecular lego player :). Developing molecular tools for live monitoring of fundamental biological processes that were not trackable before. Optimizing and developing genome engineering, gene therapy, and delivery tools.
www.cell.com/cell/fulltex...
ENVLPE, our system for VLP-based delivery of gene editors, is now published in @cellcellpress.bsky.social. We showed efficient delivery of base- and prime-editors in primary T cells & in vivo retinal models. All core constructs are available from @addgene.bsky.social.
Engineered nucleocytosolic vehicles for loading of programmable editors
Engineered nucleocytosolic vehicles for loading of programmable editors (ENVLPE) with enhanced CRISPR ribonucleoprotein (RNP) loading and stabilization enable the efficient delivery of gene-editing ef...
www.cell.com
April 9, 2025 at 11:52 PM
Reposted by Dong-Jiunn Jeffery Truong
Engineering Smart Delivery for Gene Editors 🧬
👉 t1p.de/vmdc9

Researchers from #HelmholtzMunich & @tum.de created ENVLPE – a modular, virus-like system that delivers CRISPR/Cas9 tools into cells with unprecedented efficiency.

#GeneEditing #CRISPR #CancerTherapy
April 9, 2025 at 3:22 PM