Sophie Dvali
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dvalisophie.bsky.social
Sophie Dvali
@dvalisophie.bsky.social
Biophysicists in training, PhD at Princeton University
Reposted by Sophie Dvali
Our paper on PCMD-1 and centrosome stability is finally online! Congratulations 🎉🎉🎉 to Alina and the entire team! Very proud and grateful - it was an incredible teamwork @zaninlab.bsky.social! @lifescimunich.bsky.social. If you want to read more check it out on JCB!

rupress.org/jcb/article-...
PCMD-1 stabilizes the PCM scaffold and facilitates centriole separation
Centrosome stability is essential for spindle bipolarity. Schreiner et al. show that CDK-1 primes PCMD-1 for PLK-1 phosphorylation. Mutations in PLK-1 dock
rupress.org
October 31, 2025 at 7:12 PM
Reposted by Sophie Dvali
September 22, 2025 at 5:59 PM
Congratulations Kelsey!!!
Congratulations Kelsey Hallinen, who is starting a new position as Assistant Physics Professor at University of Oregon!
September 22, 2025 at 6:10 PM
Reposted by Sophie Dvali
New findings help to explain why it has been so challenging to predict brain signaling from the connectome alone.

By Holly Barker

#neuroskyence

www.thetransmitter.org/connectome/w...
Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.
www.thetransmitter.org
August 29, 2025 at 12:05 PM
Reposted by Sophie Dvali
So stoked to see this in press!

Diverging network architecture of the C. elegans connectome and signaling network

journal: journals.aps.org/prxlife/acce...
preprint: arxiv.org/abs/2412.14498

1/3
PRX Life - Accepted Paper: Diverging network architecture of the C. elegans connectome and signaling network
journals.aps.org
August 12, 2025 at 2:11 PM
Reposted by Sophie Dvali
How do worms navigate based on learned experience? @andrewleifer.bsky.social @jpillowtime.bsky.social &co reveal flexible behavioral strategies & distributed neural computations underlying learning-dependent odor #navigation in #Celegans @plosbiology.org 🧪 plos.io/4bYZs7c
March 24, 2025 at 5:31 PM
Reposted by Sophie Dvali
p.s. the raw data from the signal propagation paper is public... so have fun exploring! dandiarchive.org/dandiset/001...
Neural signal propagation atlas of C. elegans
Data from Randi et al. Hosted on the Open Science Framework
osf.io
December 20, 2024 at 3:47 PM
Super excited to have gotten to delve in to network science and work on this with Caio Seguin, @richardfbetzel.bsky.social and @andrewleifer.bsky.social !!
December 20, 2024 at 8:49 PM
Reposted by Sophie Dvali
Congrats to Alina and the team 🎉🎉🎉!!!!! @zaninlab.bsky.social Check out our latest manuscript -> PCMD-1 stabilizes the PCM scaffold and facilitates centriole separation www.biorxiv.org/content/10.1...
PCMD-1 stabilizes the PCM scaffold and facilitates centriole separation
Centrosomes are highly dynamic organelles, and maintaining their stability is crucial for spindle pole integrity and bipolar spindle formation. Centrosomes consist of a pair of centrioles surrounded b...
www.biorxiv.org
November 16, 2024 at 7:31 AM