Alex Dubov
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dubovalex.bsky.social
Alex Dubov
@dubovalex.bsky.social
University professor 🎓 | Researcher focused on LGBTQ+ health, mental health, and HIV prevention 🏳️‍🌈 | Ukrainian 🇺🇦 in Los Angeles | 👬 @derek77.bsky.social + dads to 🦮 Milo (chocolate Lab) | Where there’s hope, there’s life (Anne Frank)
H5 bird flu detected in wastewater in New Jersey and Las Vegas, per CDC’s wastewater program.

No known cases of H5N1 bird flu have been reported in New Jersey’s poultry or dairy cattle.
January 17, 2025 at 11:12 PM
A study found that monkeys infected with an H5N1 from dairy cattle developed moderate to severe disease when exposed through the nose or windpipe. Those exposed via the mouth or stomach showed no symptoms but still shed low levels of the virus, suggesting transmission. www.nature.com/articles/s41...
Pathogenesis of bovine H5N1 clade 2.3.4.4b infection in Macaques - Nature
Nature - Pathogenesis of bovine H5N1 clade 2.3.4.4b infection in Macaques
www.nature.com
January 17, 2025 at 9:07 AM
The CDC has released a health advisory addressing the current human cases of H5N1 bird flu alongside elevated seasonal flu activity.
“For hospitalized patients testing positive for influenza type A, faster testing to identify the influenza A virus subtype is recommended.” www.cdc.gov/han/2025/han...
Health Alert Network (HAN) - 00520 | Accelerated Subtyping of Influenza A in Hospitalized PatientsMinusSASstats
www.cdc.gov
January 17, 2025 at 8:54 AM
Out of 10,600 people exposed to H5N1-infected animals, only 540 were tested, and 63 tested positive - a positivity rate over 11%, per the CDC. If all exposed were tested, we’d likely see 10-15 times more cases. Such a high positivity rate also suggests inadequate testing.
December 30, 2024 at 7:02 AM
The #H5N1 #birdflu virus identified in a severe case in Louisiana has shown mutations that may enhance its ability to attach to cells in the human respiratory tract. One of these mutations was also observed in a recent severe case in British Columbia, according to a CDC report t.co/Y17r7QFdJw
https://www.statnews.com/2024/12/26/cdc-says-h5n1-bird-flu-sample-shows-mutations-that-may-help-the-virus-bind-to-cells-in-the-upper-airways-of-people/
t.co
December 27, 2024 at 7:08 AM
Congo health ministry on outbreak: "The mystery has finally been solved. It's a case of severe malaria in the form of a respiratory illness... and weakened by malnutrition"

www.reuters.com/world/africa...
Congo's health ministry says unknown disease is severe malaria
Democratic Republic of Congo's health ministry said on Tuesday that a previously unidentified disease circulating in the country's Panzi health zone is a severe form of malaria.
www.reuters.com
December 17, 2024 at 6:31 PM
CDC's wastewater surveillance program shows H5N1 bird flu positive wastewater in 11 states.
December 14, 2024 at 6:10 PM
A retail dairy product survey was conducted that found highly pathogenic avian influenza viral RNA in both milk, cheese, butter, and ice cream, but confirmatory testing found no live virus in any sample supporting that pasteurization was effective. www.sciencedirect.com/science/arti...
Testing of retail cheese, butter, ice cream and other dairy products for highly pathogenic avian influenza in the US
The recent outbreak of highly pathogenic avian influenza (HPAI) in dairy cows has created public health concerns about the potential of consumers bein…
www.sciencedirect.com
December 14, 2024 at 6:02 PM
First hospitalization from bird flu in the US.
December 14, 2024 at 9:25 AM
Eli Lilly will start studying its obesity products as treatments for alcohol, nicotine, and drug abuse. Emerging research suggests that GLP-1 drugs not only reduce food cravings but may also suppress desires for other substances.

qz.com/eli-lilly-ze...
What can't weight-loss meds do? Eli Lilly is going to test Zepbound as a treatment for addiction
Eli Lilly CEO David Ricks said the company will start large studies "in alcohol abuse and nicotine use, even in drug abuse"
qz.com
December 12, 2024 at 8:55 AM
A 2022 Yale study found that a single-payer universal healthcare system could have saved over $105 billion in COVID hospitalization costs in 2020. Even more importantly, nearly 212,000 American lives could have been saved that year. www.pnas.org/doi/10.1073/...
Universal healthcare as pandemic preparedness: The lives and costs that could have been saved during the COVID-19 pandemic | PNAS
The fragmented and inefficient healthcare system in the United States leads to many preventable deaths and unnecessary costs every year. During a p...
www.pnas.org
December 12, 2024 at 6:41 AM
A clinical trial shows that Lenacapavir, an injectable administered twice yearly, reduces HIV infection risk by 96%, offering a promising alternative to daily oral pills like Truvada. Currently the price tag is $47k though it can be produced for $40 as a generic version.
www.nejm.org/doi/full/10....
Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons | NEJM
Twice-yearly subcutaneous lenacapavir has been shown to be efficacious for prevention of HIV infection in cisgender women. The efficacy of lenacapavir for preexposure prophylaxis (PrEP) in cisgende...
www.nejm.org
December 6, 2024 at 8:03 PM
Researchers warn that just one mutation in the bird flu virus sweeping U.S. dairy herds could make it capable of infecting human cells - a much simpler step than once thought. This mutation allows the virus to latch onto a surface protein on human cells. www.science.org/doi/10.1126/...
A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors
In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-h...
www.science.org
December 6, 2024 at 7:54 PM
Since 2010, 1 in 3 retail pharmacies has closed, with closures outpacing openings in 2018-2021. Pharmacies in Black and Latinx communities faced the highest risks. As someone working with pharmacies to introduce same-day PrEP, I’ve witnessed this trend firsthand www.healthaffairs.org/doi/abs/10.1...
More US Pharmacies Closed Than Opened In 2018–21; Independent Pharmacies, Those In Black, Latinx Communities Most At Risk | Health Affairs Journal
In recent years, federal and state policy makers have expressed concern about retail pharmacy closures throughout the US. However, there is a dearth of timely information on the extent of such closures. We linked data from the National Council for Prescription Drug Programs on all US retail pharmacies to county-level data from the National Center for Health Statistics and ZIP Code Tabulation Area data from the American Community Survey to determine the number and percentage of pharmacy closures during the period 2010–21; identify pharmacy, neighborhood, and market characteristics associated with pharmacy closure; and estimate the risk for closure for independent pharmacies relative to chain pharmacies. We found that of the 88,930 retail pharmacies operating during 2010–20, 29.4 percent had closed by 2021. The risk for closure for pharmacies in predominantly Black and Latinx neighborhoods was higher than in White neighborhoods. Independent pharmacies were at greater risk for closure than chain pharmacies across all neighborhood and market characteristics. Policy makers should consider strategies to increase the participation of independent pharmacies in Medicare and Medicaid preferred networks managed by pharmacy benefit managers and to increase public insurance reimbursement rates for pharmacies that are at the highest risk for closure.
www.healthaffairs.org
December 4, 2024 at 5:35 PM
Unknown disease kills 143 in southwest Congo, local authorities say. Infected people had flu-like symptoms, including high fever and severe headaches.

www.reuters.com/business/hea...
Unknown disease kills 143 in southwest Congo, local authorities say
An unknown disease killed 143 people in Democratic Republic of the Congo's southwestern province in November, local authorities told Reuters.
www.reuters.com
December 4, 2024 at 8:54 AM
Reposted by Alex Dubov
Clinical trial at Emory University reveals twice-yearly injection to be 99% effective in HIV prevention. news.emory.edu/stories/2024...
Clinical trial at Emory University reveals twice-yearly injection to be 99% effective in HIV prevention | Emory University | Atlanta GA
Results from a recent clinical trial led by physicians at Emory University and Grady Health System indicate that a twice-yearly injection of Lenacapavir offers a 96% reduced risk of HIV infection over...
news.emory.edu
November 30, 2024 at 5:09 PM
Thankful for road trips and our favorite travel buddy 🐾This Thanksgiving, we traded turkey for tacos and spent the holiday soaking up the beauty of Valle de Guadalupe - the perfect getaway a few hours drive from LA. Cheers to family, love, and, of course, Milo stealing the spotlight! 🦮🇲🇽
December 1, 2024 at 1:09 AM
5 Big Challenges for Misinformation Researchers:

1️⃣ Defining what “misinformation” means
2️⃣ The political nature of the issue
3️⃣ Measuring real-world impact is tricky
4️⃣ Social media platforms control the data
5️⃣ It’s a global problem with no one-size-fits-all fix

www.science.org/content/arti...
The five biggest challenges facing misinformation researchers
The burgeoning field is still grappling with fundamental problems, from getting access to data to defining 'misinformation' in the first place
www.science.org
November 30, 2024 at 8:02 PM
GLP-1 drugs have shown a 40-50% reduction in opioid overdoses and alcohol intoxication among over 1.3 million Americans with a history of opioid or alcohol use disorders. onlinelibrary.wiley.com/doi/full/10....
The association between glucose‐dependent insulinotropic polypeptide and/or glucagon‐like peptide‐1 receptor agonist prescriptions and substance‐related outcomes in patients with opioid and alcohol use disorders: A real‐world data analysis
Aims This study aimed to estimate the strength of association between prescriptions of glucose-dependent insulinotropic polypeptide (GIP) and/or glucagon-like peptide-1 receptor agonists (GLP-1 RA) ...
onlinelibrary.wiley.com
November 30, 2024 at 7:45 PM
A novel approach using LLM-based AI for mental health diagnosis analyzes subtle speech features, such as rhythm, pitch variation, and voice quality, that are often undetectable by the human ear.
November 30, 2024 at 7:43 PM
Reposted by Alex Dubov
New paper out in @ScienceMagazine! In 8 studies (multiple platforms, methods, time periods) we find: misinformation evokes more outrage than trustworthy news, when it does it's shared more + ppl are less likely to read before sharing. w/ @killianmcl1 @Klonick @mollycrockett 🧵👇
November 28, 2024 at 7:07 PM
Reposted by Alex Dubov
People with HIV will be able to receive kidney or liver transplants from donors who also have HIV, federal health officials announced Tuesday.

The landmark move, which takes effect Wednesday, is expected to shorten wait times for organs for all patients.
U.S. okays organ transplants between people with HIV, expanding donor pool
The landmark move is expected to shorten wait times for organs for all patients and reduce hurdles to life-saving care for those with HIV.
www.washingtonpost.com
November 27, 2024 at 2:49 PM