Dr Michelle L Halls
@drmlhalls.bsky.social
Spatial Organisation of Signalling lab head, Associate Professor, Deputy Theme Leader @MIPS_DDB, pharmacology/cell signalling
Reposted by Dr Michelle L Halls
🏅 Lab Olympics 2025:
From a fun idea to a real tradition, this year we’ve hit a record 6 teams in the winter marquee at MIPS! Science is serious, but these moments of connection, laughter, and (slightly) fierce competition keep us going. Here’s to teamwork and the coveted winner’s button!
From a fun idea to a real tradition, this year we’ve hit a record 6 teams in the winter marquee at MIPS! Science is serious, but these moments of connection, laughter, and (slightly) fierce competition keep us going. Here’s to teamwork and the coveted winner’s button!
August 23, 2025 at 10:43 PM
🏅 Lab Olympics 2025:
From a fun idea to a real tradition, this year we’ve hit a record 6 teams in the winter marquee at MIPS! Science is serious, but these moments of connection, laughter, and (slightly) fierce competition keep us going. Here’s to teamwork and the coveted winner’s button!
From a fun idea to a real tradition, this year we’ve hit a record 6 teams in the winter marquee at MIPS! Science is serious, but these moments of connection, laughter, and (slightly) fierce competition keep us going. Here’s to teamwork and the coveted winner’s button!
Reposted by Dr Michelle L Halls
🔉 Only a few days left to vote! 🔉
Our 2nd CCeMMP Annual Bench to Art Competition gallery is LIVE! 🤩
ccemmp.org/events/arc-c...
Vote, like and repost :)
#membraneproteins
#scicomm
#nationalscienceweek
#cryoEM
#cryoET
Our 2nd CCeMMP Annual Bench to Art Competition gallery is LIVE! 🤩
ccemmp.org/events/arc-c...
Vote, like and repost :)
#membraneproteins
#scicomm
#nationalscienceweek
#cryoEM
#cryoET
August 21, 2025 at 9:52 AM
🔉 Only a few days left to vote! 🔉
Our 2nd CCeMMP Annual Bench to Art Competition gallery is LIVE! 🤩
ccemmp.org/events/arc-c...
Vote, like and repost :)
#membraneproteins
#scicomm
#nationalscienceweek
#cryoEM
#cryoET
Our 2nd CCeMMP Annual Bench to Art Competition gallery is LIVE! 🤩
ccemmp.org/events/arc-c...
Vote, like and repost :)
#membraneproteins
#scicomm
#nationalscienceweek
#cryoEM
#cryoET
Reposted by Dr Michelle L Halls
New work in #ScienceSignaling may answer why some patients with triple-negative breast cancer who receive beta-blockers have a lower risk of metastasis and identifies a factor that holds promise as a prognostic and therapeutic target. https://scim.ag/45XmD0b
Hox-C12 coordinates β2-adrenoceptor coupling to a cAMP/calcium feedforward loop to drive invasion in triple-negative breast cancer
A GPCR and a moonlighting transcription factor together drive metastasis in breast cancer.
scim.ag
August 20, 2025 at 4:22 PM
New work in #ScienceSignaling may answer why some patients with triple-negative breast cancer who receive beta-blockers have a lower risk of metastasis and identifies a factor that holds promise as a prognostic and therapeutic target. https://scim.ag/45XmD0b
Our latest paper from @monashuniversity.bsky.social Monash Institute of Pharmaceutical Sciences led by #PhD student Terrance Lam is out in Science Signaling today. We investigated how #GPCR #signalling can accelerate invasion in TNBC.
August 19, 2025 at 9:33 PM
Our latest paper from @monashuniversity.bsky.social Monash Institute of Pharmaceutical Sciences led by #PhD student Terrance Lam is out in Science Signaling today. We investigated how #GPCR #signalling can accelerate invasion in TNBC.
Reposted by Dr Michelle L Halls
See more terrific pieces from Hayley here.
www.abc.net.au/news/hayley-...
www.abc.net.au/news/hayley-...
Hayley Gleeson - ABC News
www.abc.net.au
December 29, 2024 at 4:41 AM
See more terrific pieces from Hayley here.
www.abc.net.au/news/hayley-...
www.abc.net.au/news/hayley-...
Reposted by Dr Michelle L Halls
The PDB files for the TSC:WIPI3 complex have been released today at the PDB. At 40nm across, it is well worth a look 😀🧪
www.rcsb.org/structure/9CE3
www.rcsb.org/structure/9CE3
RCSB PDB - 9CE3: Structure of the TSC:WIPI3 lysosomal recruitment complex
Structure of the TSC:WIPI3 lysosomal recruitment complex
www.rcsb.org
December 4, 2024 at 8:15 AM
The PDB files for the TSC:WIPI3 complex have been released today at the PDB. At 40nm across, it is well worth a look 😀🧪
www.rcsb.org/structure/9CE3
www.rcsb.org/structure/9CE3
Reposted by Dr Michelle L Halls
Our latest study is now online at Science Advances! We report the structure of the gigantic TSC:WIPI3 complex revealing new insights into lysosomal docking and dysregulation in disease. #cryoEM #mTOR 🧪
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
November 20, 2024 at 9:32 PM
Our latest study is now online at Science Advances! We report the structure of the gigantic TSC:WIPI3 complex revealing new insights into lysosomal docking and dysregulation in disease. #cryoEM #mTOR 🧪
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Dr Michelle L Halls
We had a great time yesterday at the Children's Tumour Foundation Australia Conquer #NF in Colour event in Melbourne. It was great to join so many others in supporting the important work of #CTFAustralia, who advocate for and support the 1:3000 people who are diagnosed NF.
November 18, 2024 at 5:43 AM
We had a great time yesterday at the Children's Tumour Foundation Australia Conquer #NF in Colour event in Melbourne. It was great to join so many others in supporting the important work of #CTFAustralia, who advocate for and support the 1:3000 people who are diagnosed NF.
Congratulations to #PhD students @ChantelMastos, @TerranceLamm, and @EricLe_1 who recently won the best talk, people's choice best talk, and best 3MT prizes at the 19th annual HDR symposium and @MIPS_DDB student symposium @MonashPharm @MIPSAustralia 🙌
November 15, 2024 at 6:06 AM
Congratulations to #PhD students @ChantelMastos, @TerranceLamm, and @EricLe_1 who recently won the best talk, people's choice best talk, and best 3MT prizes at the 19th annual HDR symposium and @MIPS_DDB student symposium @MonashPharm @MIPSAustralia 🙌
Reposted by Dr Michelle L Halls
Very exciting! Thanks to Cell Press, Arun Shukla, and the team for the Preview article on our recent advances in uncovering the structure of LYCHOS/GPR155!
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Bound by the love for cholesterol: A transporter meets a GPCR
In a recent issue of Nature, Bayly-Jones et al. report the cryo-EM structures of a
lysosomal cholesterol sensor, LYCHOS, also known as GPR155, which reveals a unique
fusion of a plant auxin-transporte...
www.cell.com
November 14, 2024 at 7:46 PM
Very exciting! Thanks to Cell Press, Arun Shukla, and the team for the Preview article on our recent advances in uncovering the structure of LYCHOS/GPR155!
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Reposted by Dr Michelle L Halls
Another really nice highlight of our recent work. Arun et al raise interesting points about membrane cross talk and next-steps for LYCHOS. www.cell.com/cell/abstrac...
Bound by the love for cholesterol: A transporter meets a GPCR
In a recent issue of Nature, Bayly-Jones et al. report the cryo-EM structures of a
lysosomal cholesterol sensor, LYCHOS, also known as GPR155, which reveals a unique
fusion of a plant auxin-transporte...
www.cell.com
November 14, 2024 at 9:32 PM
Another really nice highlight of our recent work. Arun et al raise interesting points about membrane cross talk and next-steps for LYCHOS. www.cell.com/cell/abstrac...