Dr Matteo Fabbri
@drmatteofabbri.bsky.social
Cardiology fellow at Inova. My opinions are my own. He/Him. BLM. Passionate about heart failure and pulmonary hypertension. ❤️
Dr Bilgili showed us the outcomes after OHTx divided by need of ECMO at 72 hours post surgery. ECMO need at 72 hours greatly worsens survival.
April 30, 2025 at 5:58 PM
Dr Bilgili showed us the outcomes after OHTx divided by need of ECMO at 72 hours post surgery. ECMO need at 72 hours greatly worsens survival.
Dr Huang shows pre and post allocation change status change in immunosuppression and outcomes among multi-organ transplant.
Super interesting data. @ishlt.bsky.social #ISHLT2025
Super interesting data. @ishlt.bsky.social #ISHLT2025
April 30, 2025 at 5:49 PM
Dr Huang shows pre and post allocation change status change in immunosuppression and outcomes among multi-organ transplant.
Super interesting data. @ishlt.bsky.social #ISHLT2025
Super interesting data. @ishlt.bsky.social #ISHLT2025
Dr Elbert Heng shows amazing study on survival of patients with ACHD receiving OHTx vs multiorgan transplant alone.
❤️ and 🫁 carry the worse survival so far.
@ishlt.bsky.social #ISHLT2025
❤️ and 🫁 carry the worse survival so far.
@ishlt.bsky.social #ISHLT2025
April 30, 2025 at 5:35 PM
Dr Elbert Heng shows amazing study on survival of patients with ACHD receiving OHTx vs multiorgan transplant alone.
❤️ and 🫁 carry the worse survival so far.
@ishlt.bsky.social #ISHLT2025
❤️ and 🫁 carry the worse survival so far.
@ishlt.bsky.social #ISHLT2025
Dr Paula Ramirez shows us their new predictive models to discriminate if ❤️ and kidney transplant is superior to kidney after ❤️. Beautiful work which can help change clinical practice at #ISHLT2025 @ishlt.bsky.social
April 30, 2025 at 5:22 PM
Dr Paula Ramirez shows us their new predictive models to discriminate if ❤️ and kidney transplant is superior to kidney after ❤️. Beautiful work which can help change clinical practice at #ISHLT2025 @ishlt.bsky.social
Amazing work presented from Dr Topkara who developed a kidney risk score which predicts the risk for AKI/HD after ❤️ transplant! High AUC, higher than eGFR alone!
#ISHLT2025 @ishlt.bsky.social
#ISHLT2025 @ishlt.bsky.social
April 30, 2025 at 5:10 PM
Amazing work presented from Dr Topkara who developed a kidney risk score which predicts the risk for AKI/HD after ❤️ transplant! High AUC, higher than eGFR alone!
#ISHLT2025 @ishlt.bsky.social
#ISHLT2025 @ishlt.bsky.social
Dr Hussain showed us a single center experience of Fontain patients receiving ❤️ transplant. Should they get a liver as well? Seems like all 24 of them had recovery of the liver function after transplant without needing a a new liver.
Great science at #ISHLT2025 @ishlt.bsky.social
Great science at #ISHLT2025 @ishlt.bsky.social
April 30, 2025 at 4:56 PM
Dr Hussain showed us a single center experience of Fontain patients receiving ❤️ transplant. Should they get a liver as well? Seems like all 24 of them had recovery of the liver function after transplant without needing a a new liver.
Great science at #ISHLT2025 @ishlt.bsky.social
Great science at #ISHLT2025 @ishlt.bsky.social
Finally we talk about induction with Dr Barten. To induce or not to induce? This is the dilemma!
And Dr Carboni showed us how AI can be implemented in helping us with HLA matching.
And Dr Carboni showed us how AI can be implemented in helping us with HLA matching.
April 30, 2025 at 4:46 PM
Finally we talk about induction with Dr Barten. To induce or not to induce? This is the dilemma!
And Dr Carboni showed us how AI can be implemented in helping us with HLA matching.
And Dr Carboni showed us how AI can be implemented in helping us with HLA matching.
It’s AB0ut time we talk with Dr Aversa about AB0! Super interesting case of an 0 patient receiving nonA1 🫁 transplant with no signs of rejections.
Incredible science showed at #ISHLT2025 @ishlt.bsky.social
Incredible science showed at #ISHLT2025 @ishlt.bsky.social
April 30, 2025 at 4:44 PM
It’s AB0ut time we talk with Dr Aversa about AB0! Super interesting case of an 0 patient receiving nonA1 🫁 transplant with no signs of rejections.
Incredible science showed at #ISHLT2025 @ishlt.bsky.social
Incredible science showed at #ISHLT2025 @ishlt.bsky.social
Followed by Dr Guillaime Coutance guiding us through PRAs. Which antibodies should we look for and how to measure???
Dr Lyster showed us what to do with highly sensitised patients pre and post transplant.
#ISHLT2025
Dr Lyster showed us what to do with highly sensitised patients pre and post transplant.
#ISHLT2025
April 30, 2025 at 4:41 PM
Followed by Dr Guillaime Coutance guiding us through PRAs. Which antibodies should we look for and how to measure???
Dr Lyster showed us what to do with highly sensitised patients pre and post transplant.
#ISHLT2025
Dr Lyster showed us what to do with highly sensitised patients pre and post transplant.
#ISHLT2025
And last day at #ISHLT2025 we go through the consensus statement with Dr Annette Jackson. Amazing talk on the use of antibodies in transplant.
@ishlt.bsky.social
@ishlt.bsky.social
April 30, 2025 at 4:38 PM
And last day at #ISHLT2025 we go through the consensus statement with Dr Annette Jackson. Amazing talk on the use of antibodies in transplant.
@ishlt.bsky.social
@ishlt.bsky.social
This morning at ISHLT I’m sensing a theme, let’s see if any of you catch on that. Rare causes of PH.
@ishlt.bsky.social
#PAH
#PH
#Rightventricle
#rare
@ishlt.bsky.social
#PAH
#PH
#Rightventricle
#rare
April 29, 2025 at 2:26 PM
This morning at ISHLT I’m sensing a theme, let’s see if any of you catch on that. Rare causes of PH.
@ishlt.bsky.social
#PAH
#PH
#Rightventricle
#rare
@ishlt.bsky.social
#PAH
#PH
#Rightventricle
#rare
We finish with a great talk from the amazing @nickbruin.bsky.social about the Delphi consensus.
Refer early and often
Reassess your patient. 🫁 transplant save lives and improves quality of life in PAH
#PAH #PH #lungtransplant #ISHLT2025
@ishlt.bsky.social
onlinelibrary.wiley.com/doi/full/10....
Refer early and often
Reassess your patient. 🫁 transplant save lives and improves quality of life in PAH
#PAH #PH #lungtransplant #ISHLT2025
@ishlt.bsky.social
onlinelibrary.wiley.com/doi/full/10....
Approach to Lung Transplantation in Pulmonary Arterial Hypertension: A Delphi Consensus on Behalf of the Transplant Task Force of the Pulmonary Vascular Research Institute
Lung transplantation is indicated for selected patients with advanced pulmonary arterial hypertension (PAH). We used a modified Delphi process to develop recommendations on care of patients with PAH ...
onlinelibrary.wiley.com
April 28, 2025 at 7:04 PM
We finish with a great talk from the amazing @nickbruin.bsky.social about the Delphi consensus.
Refer early and often
Reassess your patient. 🫁 transplant save lives and improves quality of life in PAH
#PAH #PH #lungtransplant #ISHLT2025
@ishlt.bsky.social
onlinelibrary.wiley.com/doi/full/10....
Refer early and often
Reassess your patient. 🫁 transplant save lives and improves quality of life in PAH
#PAH #PH #lungtransplant #ISHLT2025
@ishlt.bsky.social
onlinelibrary.wiley.com/doi/full/10....
What is the role of MCS in PAH and cardiogenic shock?
1) patient selection
2) choose the RIGHT access
3) have an exit strategy in view
4) start PH therapies
5) consider transplant
These are few of the points we discussed today with Dr Sommer @ishlt.bsky.social
#ISHLT #PAH #PH
1) patient selection
2) choose the RIGHT access
3) have an exit strategy in view
4) start PH therapies
5) consider transplant
These are few of the points we discussed today with Dr Sommer @ishlt.bsky.social
#ISHLT #PAH #PH
April 28, 2025 at 7:02 PM
What is the role of MCS in PAH and cardiogenic shock?
1) patient selection
2) choose the RIGHT access
3) have an exit strategy in view
4) start PH therapies
5) consider transplant
These are few of the points we discussed today with Dr Sommer @ishlt.bsky.social
#ISHLT #PAH #PH
1) patient selection
2) choose the RIGHT access
3) have an exit strategy in view
4) start PH therapies
5) consider transplant
These are few of the points we discussed today with Dr Sommer @ishlt.bsky.social
#ISHLT #PAH #PH
What can you do when a patient with PH land in the ICU with Shock?
Dr Mads Andersen walks us through
Preload treatment
Inotropes and its use
Afterload for PH
Important talk @ishlt.bsky.social #ISHLT2025 #PH
Dr Mads Andersen walks us through
Preload treatment
Inotropes and its use
Afterload for PH
Important talk @ishlt.bsky.social #ISHLT2025 #PH
April 28, 2025 at 7:01 PM
What can you do when a patient with PH land in the ICU with Shock?
Dr Mads Andersen walks us through
Preload treatment
Inotropes and its use
Afterload for PH
Important talk @ishlt.bsky.social #ISHLT2025 #PH
Dr Mads Andersen walks us through
Preload treatment
Inotropes and its use
Afterload for PH
Important talk @ishlt.bsky.social #ISHLT2025 #PH
And from the Right Ventricle- Right atria interaction we move to the complex relationship between heart - kidneys and lungs in PH with an amazing talk from Dr. Rosenkranz.
#ISHLT2025 #PAH #PH
@ishlt.bsky.social
#ISHLT2025 #PAH #PH
@ishlt.bsky.social
April 28, 2025 at 7:00 PM
And from the Right Ventricle- Right atria interaction we move to the complex relationship between heart - kidneys and lungs in PH with an amazing talk from Dr. Rosenkranz.
#ISHLT2025 #PAH #PH
@ishlt.bsky.social
#ISHLT2025 #PAH #PH
@ishlt.bsky.social
Today we dig deep in the pathophys of PH #ISHLT2025 with Dr Frances De Man on pressure loop of the RA.
Super interesting discussion on what happens to myocites in the right atrium.
@ishlt.bsky.social #PAH #PH
Super interesting discussion on what happens to myocites in the right atrium.
@ishlt.bsky.social #PAH #PH
April 28, 2025 at 6:59 PM
Today we dig deep in the pathophys of PH #ISHLT2025 with Dr Frances De Man on pressure loop of the RA.
Super interesting discussion on what happens to myocites in the right atrium.
@ishlt.bsky.social #PAH #PH
Super interesting discussion on what happens to myocites in the right atrium.
@ishlt.bsky.social #PAH #PH
Today @ishlt.bsky.social in Boston we talked about Pulmonary Hypertension.
Here the main take-away from the Updates on the 7th World Symposium.
Here the main take-away from the Updates on the 7th World Symposium.
April 27, 2025 at 8:36 PM
Today @ishlt.bsky.social in Boston we talked about Pulmonary Hypertension.
Here the main take-away from the Updates on the 7th World Symposium.
Here the main take-away from the Updates on the 7th World Symposium.
Reposted by Dr Matteo Fabbri
In people with diabetes, GLP-1 and SGLT2i drugs were associated with less Alzheimer's disease and related dementias
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
April 7, 2025 at 3:06 PM
In people with diabetes, GLP-1 and SGLT2i drugs were associated with less Alzheimer's disease and related dementias
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Another study on the striking effect of sotatercept in PAH patients with elevated REVEAL score.
Findings are not subtle at all! Trial stopped early with composite outcome of death, 🫁 transplant or hospitalization HR 0.24 (95%CI 0.13-0.43)
www.nejm.org/doi/full/10....
Findings are not subtle at all! Trial stopped early with composite outcome of death, 🫁 transplant or hospitalization HR 0.24 (95%CI 0.13-0.43)
www.nejm.org/doi/full/10....
Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death | NEJM
Sotatercept improves exercise capacity and delays the time to clinical worsening in patients with World Health Organization (WHO) functional class II or III pulmonary arterial hypertension. The eff...
www.nejm.org
March 31, 2025 at 5:24 PM
Another study on the striking effect of sotatercept in PAH patients with elevated REVEAL score.
Findings are not subtle at all! Trial stopped early with composite outcome of death, 🫁 transplant or hospitalization HR 0.24 (95%CI 0.13-0.43)
www.nejm.org/doi/full/10....
Findings are not subtle at all! Trial stopped early with composite outcome of death, 🫁 transplant or hospitalization HR 0.24 (95%CI 0.13-0.43)
www.nejm.org/doi/full/10....
Reposted by Dr Matteo Fabbri
DAPA-TAVI: The #SGLT2 inhibitor dapagliflozin was superior to standard care alone in decreasing rates of all-cause mortality or worsening #HeartFailure in older adults w/ #vhdAS undergoing TAVI, resulting in a 28% relative risk ↘️. #ACC25
More: bit.ly/4cfLNsy
#cvSurg #CardioSky #MedSky
More: bit.ly/4cfLNsy
#cvSurg #CardioSky #MedSky
March 29, 2025 at 10:22 PM
DAPA-TAVI: The #SGLT2 inhibitor dapagliflozin was superior to standard care alone in decreasing rates of all-cause mortality or worsening #HeartFailure in older adults w/ #vhdAS undergoing TAVI, resulting in a 28% relative risk ↘️. #ACC25
More: bit.ly/4cfLNsy
#cvSurg #CardioSky #MedSky
More: bit.ly/4cfLNsy
#cvSurg #CardioSky #MedSky
Reposted by Dr Matteo Fabbri
Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome. @naturemedicine.bsky.social
March 24, 2025 at 4:03 PM
Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome. @naturemedicine.bsky.social
Vutrisiran is now approved for aTTR cardiac amyloid! Another medication to help these patients!
www.businesswire.com/news/home/20...
www.businesswire.com/news/home/20...
Alnylam Announces FDA Approval of AMVUTTRA® (vutrisiran), the First RNAi Therapeutic to Reduce Cardiovascular Death, Hospitalizations and Urgent Heart Failure Visits in Adults with ATTR Amyloidosis wi...
Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced the U.S. Food and Drug Administration (FDA) approval of ...
www.businesswire.com
March 22, 2025 at 3:26 PM
Vutrisiran is now approved for aTTR cardiac amyloid! Another medication to help these patients!
www.businesswire.com/news/home/20...
www.businesswire.com/news/home/20...
One of my best friends:
Create your Instagram and find happiness, Stop being a Hippie already!
@alvarezsoto.bsky.social
Create your Instagram and find happiness, Stop being a Hippie already!
@alvarezsoto.bsky.social
February 4, 2025 at 3:08 AM
One of my best friends:
Create your Instagram and find happiness, Stop being a Hippie already!
@alvarezsoto.bsky.social
Create your Instagram and find happiness, Stop being a Hippie already!
@alvarezsoto.bsky.social
Linguine with mussels. ❤️
January 4, 2025 at 2:11 AM
Linguine with mussels. ❤️
Check out this paper from Sweden. Long term use of LDL lowering meds and anti-HTN meds was associated with lower the odds of dementia in this case-control study.
No reason not to lower BP and cholesterol.
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
No reason not to lower BP and cholesterol.
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Use of common cardiovascular disease drugs and risk of dementia: A case–control study in Swedish national register data
INTRODUCTION Cardiovascular drug use may help prevent dementia; however, current evidence is mixed. Using a case–control design, we investigated the association between duration and combination of m...
alz-journals.onlinelibrary.wiley.com
December 23, 2024 at 4:32 PM
Check out this paper from Sweden. Long term use of LDL lowering meds and anti-HTN meds was associated with lower the odds of dementia in this case-control study.
No reason not to lower BP and cholesterol.
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
No reason not to lower BP and cholesterol.
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...