Dr Helen Roberts
@drhelenroberts.bsky.social
Associate Professor in Skeletal Cancer Research, Co-Director of the Centre for Investigative and Diagnostic Oncology, Director of Programmes at Middlesex University
What a beautiful image! Congratulations @drsjroberts.bsky.social!
Cover image showing pseudo-colored trabeculae of the Sost -/- proximal tibiae, highlighting how bone thickness varies, measured by µCT. This cover image was contributed by @Scott Roberts, the Royal Veterinary College, London, UK.
@brjournal.bsky.social
www.nature.com/articles/s41...
@brjournal.bsky.social
www.nature.com/articles/s41...
August 29, 2025 at 7:29 AM
What a beautiful image! Congratulations @drsjroberts.bsky.social!
Reposted by Dr Helen Roberts
New research!
We're proud to be funding a study with @cclguk.bsky.social which could uncover new treatments for osteosarcoma 🔬
Led by Prof Plevin @unistrathclyde.bsky.social, the team will investigate a protein called IKKα and whether blocking it could stop cell growth.
Visit: ow.ly/WnwT50VGhfj
We're proud to be funding a study with @cclguk.bsky.social which could uncover new treatments for osteosarcoma 🔬
Led by Prof Plevin @unistrathclyde.bsky.social, the team will investigate a protein called IKKα and whether blocking it could stop cell growth.
Visit: ow.ly/WnwT50VGhfj
April 25, 2025 at 10:03 AM
New research!
We're proud to be funding a study with @cclguk.bsky.social which could uncover new treatments for osteosarcoma 🔬
Led by Prof Plevin @unistrathclyde.bsky.social, the team will investigate a protein called IKKα and whether blocking it could stop cell growth.
Visit: ow.ly/WnwT50VGhfj
We're proud to be funding a study with @cclguk.bsky.social which could uncover new treatments for osteosarcoma 🔬
Led by Prof Plevin @unistrathclyde.bsky.social, the team will investigate a protein called IKKα and whether blocking it could stop cell growth.
Visit: ow.ly/WnwT50VGhfj
Reposted by Dr Helen Roberts
📋 Importance: LGK974 therapy would likely be an option for treating disease early in children. This would potentially avoid risky surgical treatments such as skull decompression surgery.
April 22, 2025 at 5:21 PM
📋 Importance: LGK974 therapy would likely be an option for treating disease early in children. This would potentially avoid risky surgical treatments such as skull decompression surgery.
Reposted by Dr Helen Roberts
💡A huge shout out to all of the authors of this study Tim Dreyer, Jacob Keen, Leah Wells, Mark Hopkinson, Isabel Orriss, Gill Holdsworth and Andy Pitsillides - you are all great! Also many thanks to our funders UCB Pharma for your continued support.
April 22, 2025 at 5:22 PM
💡A huge shout out to all of the authors of this study Tim Dreyer, Jacob Keen, Leah Wells, Mark Hopkinson, Isabel Orriss, Gill Holdsworth and Andy Pitsillides - you are all great! Also many thanks to our funders UCB Pharma for your continued support.
Reposted by Dr Helen Roberts
💊 What We Found: A drug called LGK974 reduced skull and ear bone mass of young mice with sclerosteosis disease, indicating that it effectively limits skeletal overgrowth at sites with severe/fatal pathology.
April 22, 2025 at 5:20 PM
💊 What We Found: A drug called LGK974 reduced skull and ear bone mass of young mice with sclerosteosis disease, indicating that it effectively limits skeletal overgrowth at sites with severe/fatal pathology.
Reposted by Dr Helen Roberts
📢 New Publication: I am delighted to share our most recent paper, published in @natureportfolio.nature.com Journal Bone Research "Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies".
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies - Bone Research
Bone Research - Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies
www.nature.com
April 22, 2025 at 5:18 PM
📢 New Publication: I am delighted to share our most recent paper, published in @natureportfolio.nature.com Journal Bone Research "Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies".
www.nature.com/articles/s41...
www.nature.com/articles/s41...