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brjournal.bsky.social
Bone Research_Editorial Office
@brjournal.bsky.social
31 followers 88 following 54 posts
Bone Research is an open access, fully peer-reviewed journal publishing the foremost progress and novel understanding of all aspects of bone science.
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brjournal.bsky.social
Extracellular vesicles (EVs) are tiny bubbles cells release that can carry healing substances. They might help treat osteoarthritis by delivering drugs directly to affected joints, offering a new way to manage this common joint disease.😀
#EVs
@brjournal.bsky.social
www.nature.com/articles/s41...
January 14, 2026 at 7:33 AM
brjournal.bsky.social
Osteoporosis may boost dementia risk in seniors, especially after fractures. Better bone health care could help prevent both, offering new insights for managing aging health.😀
#osteoporosis #dementia #bone
@brjournal.bsky.social
www.nature.com/articles/s41...
January 9, 2026 at 7:27 AM
brjournal.bsky.social
Neurofibromatosis type 1 (NF1) causes spine deformities. New study using a mouse model reveals the cellular cause and suggests a treatment that could prevent these deformities, offering hope for better management of NF1.😀
#NF1 #bone
@brjournal.bsky.social
www.nature.com/articles/s41...
January 6, 2026 at 3:20 AM
brjournal.bsky.social
Bone marrow fluid from newborns boosts stem cells' bone-making abilities more than adult fluid or standard serum, offering a promising tool for healing bone.😀
#bone
@brjournal.bsky.social
www.nature.com/articles/s41...
December 31, 2025 at 9:43 AM
brjournal.bsky.social
Overexpressing Ribosomal Protein S17 (RPS17) in immune cells may help treat Ankylosing Spondylitis (AS) by easing inflammation and preventing bone loss, offering a promising new approach!😀
#bone
@brjournal.bsky.social
www.nature.com/articles/s41...
December 26, 2025 at 1:36 AM
brjournal.bsky.social
Losing weight can thin your bones too; this review explains why rapid slimming raises fracture risk and how to protect your skeleton while shedding pounds.😀
#weight #bone #skeleton
@brjournal.bsky.social
www.nature.com/articles/s41...
December 23, 2025 at 2:37 AM
brjournal.bsky.social
The brain talks to bones through nerves and chemical messengers; calming this “brain-bone chat” could offer new ways to fight osteoporosis and other skeletal diseases, guiding future therapies for healthier aging.😀
#bone #brain #osteoporosis
@brjournal.bsky.social
www.nature.com/articles/s41...
December 16, 2025 at 8:10 AM
brjournal.bsky.social
The Survival of Motor Neuron (SMN) protein is key for bone health by controlling gene function and protein breakdown. Studying it in Severe Spinal Muscular Atrophy (SMA) mice helps understand bone issues in patients, guiding future treatments.👇
@brjournal.bsky.social
www.nature.com/articles/s41...
December 12, 2025 at 5:11 AM
brjournal.bsky.social
A new review study delivers a holistic overview of bone healing! It synthesizes mechanisms (inflammatory balance, repair substance supply), current strategies (bioactive factors, stem cells, smart biomaterials), and cutting-edge biosensor monitoring.😀
www.nature.com/articles/s41...
December 9, 2025 at 5:13 AM
brjournal.bsky.social
Osteomyelitis, a tough bone infection, often recurs despite treatment. This review highlights how biomaterials can direct immune cells to fight infections more effectively, offering hope for better therapies.😀
#Osteomyelitis #bone
@brjournal.bsky.social
www.nature.com/articles/s41...
December 3, 2025 at 3:38 AM
brjournal.bsky.social
Bone marrow lesions (BML) are early signs of osteoarthritis (OA). Researchers studied BML and cartilage interactions, finding that certain cells drive OA progression through inflammation and aging. This helps in developing new treatments for OA.
@brjournal.bsky.social
www.nature.com/articles/s41...
December 2, 2025 at 5:21 AM
brjournal.bsky.social
By studying Sirtuin 5 (Sirt5) in mice, researchers discovered a key mechanism linking mitochondrial health to bone strength, offering new hope for treating osteoporosis.👇
#Sirt5 #osteoporosis #bone
@brjournal.bsky.social
www.nature.com/articles/s41...
November 28, 2025 at 3:28 AM
brjournal.bsky.social
Researchers demonstrated in mice that deleting hypertrophic chondrocyte descendants impairs bone growth and healing. This revealed the cells' role in secreting factors such as thrombospondin-4, which is essential for blood vessel formation.😀
@brjournal.bsky.social
www.nature.com/articles/s41...
November 27, 2025 at 2:15 AM
brjournal.bsky.social
Investigating circadian rhythm regulation, a study finds Gala-SR, a small-molecule compound, effectively restores rhythm disorders and mitigates inflammation in periodontitis, offering potential for treating inflammatory diseases.👍
#bone
@brjournal.bsky.social
www.nature.com/articles/s41...
November 21, 2025 at 7:55 AM
brjournal.bsky.social
Exploring the links between ossification of the posterior longitudinal ligament and endocrine-metabolic dysregulation, a review highlights potential factors and pathways, crucial for advancing early intervention and therapeutic strategies.😀
@brjournal.bsky.social
www.nature.com/articles/s41...
November 19, 2025 at 6:34 AM
brjournal.bsky.social
Discogenic lower back pain is a distinct pathological entity linked to intervertebral disc degeneration. Recent review synthesizes current knowledge on its pathophysiology, risk factors, and diagnostic challenges, highlighting the need for targeted treatments.👇
#bone
www.nature.com/articles/s41...
November 14, 2025 at 2:38 AM
brjournal.bsky.social
Traumatic heterotopic ossification (HO) is an abnormal bone formation after injury. A study explores how necroptotic macrophages and p21-activated kinase 4 (Pak4) influence this process, revealing potential therapeutic targets.👍
#bone #Pak4
@brjournal.bsky.social
www.nature.com/articles/s41...
November 11, 2025 at 5:46 AM
brjournal.bsky.social
Osteoarthritis (OA), a common joint disorder, is a significant global healthcare challenge. This review explores how advanced materials and AI enhance OA diagnosis and treatment, offering insights for next-generation smart materials with improved performance.😀
#joint
www.nature.com/articles/s41...
November 7, 2025 at 5:20 AM
brjournal.bsky.social
cPLA2, a key inflammation mediator, drives cartilage degeneration in osteoarthritis (OA) and intervertebral disc degeneration (IVDD). Inhibiting it reduces inflammation and preserves cartilage, offering hope for new therapies.👇
#osteoarthritis
@brjournal.bsky.social
www.nature.com/articles/s41...
November 7, 2025 at 5:16 AM
brjournal.bsky.social
A new review explores how aging affects osteoarthritis, identifying immune imbalance, cell aging, and stem cell exhaustion as key factors, guiding future treatments.👇
#osteoarthritis #cell #bone #aging
@brjournal.bsky.social
www.nature.com/articles/s41...
October 31, 2025 at 2:36 AM
brjournal.bsky.social
Using bone injury strategies, a recent study explores diabetic patients' foot wound healing, revealing osteokines' role in accelerating repair and offering new treatment insights.😀
#bone #diabetic #osteokines
@brjournal.bsky.social
www.nature.com/articles/s41...
October 30, 2025 at 8:02 AM
brjournal.bsky.social
Dendritic cells play a key role in bone repair and regeneration. New research explores their impact on bone health and potential for innovative treatments in osteoimmunology！😀
#osteoimmunology #bone
@brjournal.bsky.social
www.nature.com/articles/s41...
October 24, 2025 at 3:40 AM
brjournal.bsky.social
Piezo1, a key protein in bone health, boosts fracture healing by enhancing mitochondrial energy production. A new study shows it works through a pathway involving β-catenin and Lars2, offering new ways to treat fractures！👇
#Piezo1 #bone #Lars2
@brjournal.bsky.social
www.nature.com/articles/s41...
October 22, 2025 at 6:00 AM
brjournal.bsky.social
According to a new study, basic fibroblast growth factor (FGF2), a key protein, regulates rRNA expression in stem cells via chromatin architecture, impacting cell fate and proliferation. These insights could enhance regenerative medicine and tissue engineering!👍
#bone
www.nature.com/articles/s41...
October 17, 2025 at 1:50 AM
brjournal.bsky.social
Sarcopenia, or muscle loss in the elderly, is linked to falls, fractures, and other issues. This review explores its connection to musculoskeletal disorders and potential treatments, helping develop targeted interventions！👍
#sarcopenia #bone
@brjournal.bsky.social
www.nature.com/articles/s41...
October 13, 2025 at 9:12 AM