Brett J. Manley 🤷🏼♂️
@drbretty.bsky.social
Neonatologist and Professor of Newborn Medicine, Mercy Hospital for Women and The University of Melbourne, Melbourne, Australia | Co-PI of @platipus.bsky.social
Pinned
Save the dates for Cool Topics in Neonatology 😎
November 27-28, Melbourne 🇦🇺🦘
With:
⭐️ Anup Katheria 🇺🇸
⭐️ Neena Modi 🇬🇧
⭐️ Richard Martin 🇺🇸
… and many more!
Additional workshops and details to be announced in the coming months.
November 27-28, Melbourne 🇦🇺🦘
With:
⭐️ Anup Katheria 🇺🇸
⭐️ Neena Modi 🇬🇧
⭐️ Richard Martin 🇺🇸
… and many more!
Additional workshops and details to be announced in the coming months.
Reposted by Brett J. Manley 🤷🏼♂️
Caffeine is good for the preterm brain; might more caffeine be even better?
One of the pivotal RCTs in neonatology was the CAP study (Schmidt B, et al. Long-term effects of caffeine therapy for apnea of prematurity. N Engl J Med. 2007;357(19):1893–902). We performed that study because there was no…
One of the pivotal RCTs in neonatology was the CAP study (Schmidt B, et al. Long-term effects of caffeine therapy for apnea of prematurity. N Engl J Med. 2007;357(19):1893–902). We performed that study because there was no…
Caffeine is good for the preterm brain; might more caffeine be even better?
One of the pivotal RCTs in neonatology was the CAP study (Schmidt B, et al. Long-term effects of caffeine therapy for apnea of prematurity. N Engl J Med. 2007;357(19):1893–902). We performed that study because there was no data on the long term impacts of caffeine, and there was a worry that blocking adenosine receptors in babies having multiple hypoxic episodes might be a bad idea. Adenosine is an inhibitory neurotransmitter that is produced during hypoxia, and decreases the brain metabolic rate to protect against hypoxic damage. So giving caffeine to babies having a lot of apnoeas could potentially have been a bad idea.
neonatalresearch.org
September 24, 2025 at 7:21 PM
Caffeine is good for the preterm brain; might more caffeine be even better?
One of the pivotal RCTs in neonatology was the CAP study (Schmidt B, et al. Long-term effects of caffeine therapy for apnea of prematurity. N Engl J Med. 2007;357(19):1893–902). We performed that study because there was no…
One of the pivotal RCTs in neonatology was the CAP study (Schmidt B, et al. Long-term effects of caffeine therapy for apnea of prematurity. N Engl J Med. 2007;357(19):1893–902). We performed that study because there was no…
Global Neonatal Journal Club
Sept 24th 1700 AEST
Discussing: Lancet Commission on the Future of Neonatology, incl. interviews w/ Danny DeLuca & Steve Abman
Featuring: Arti Maria, Alex Stevenson, Hoang Thi Tran, Patrick Too, Tendai Mutema & Peter Davis
mercyhealthau.zoom.us/webinar/regist…
Sept 24th 1700 AEST
Discussing: Lancet Commission on the Future of Neonatology, incl. interviews w/ Danny DeLuca & Steve Abman
Featuring: Arti Maria, Alex Stevenson, Hoang Thi Tran, Patrick Too, Tendai Mutema & Peter Davis
mercyhealthau.zoom.us/webinar/regist…
https://nowmercyhealthau.zoom.us/webinar/regist…
September 13, 2025 at 2:36 AM
Global Neonatal Journal Club
Sept 24th 1700 AEST
Discussing: Lancet Commission on the Future of Neonatology, incl. interviews w/ Danny DeLuca & Steve Abman
Featuring: Arti Maria, Alex Stevenson, Hoang Thi Tran, Patrick Too, Tendai Mutema & Peter Davis
mercyhealthau.zoom.us/webinar/regist…
Sept 24th 1700 AEST
Discussing: Lancet Commission on the Future of Neonatology, incl. interviews w/ Danny DeLuca & Steve Abman
Featuring: Arti Maria, Alex Stevenson, Hoang Thi Tran, Patrick Too, Tendai Mutema & Peter Davis
mercyhealthau.zoom.us/webinar/regist…
Reposted by Brett J. Manley 🤷🏼♂️
NEONATAL RESPIRATORY TRIALS IN SICK & PRETERM NEWBORN INFANTS With Professor Brett Manley, Consultant Neonatologist Mercy Hospital For Women, Melbourne & Professor of Neonatal Medicine Department of Obstetrics, Gynaecology and Newborn Health, University of Melbourne, Australia youtu.be/NAY_0xBGsrw
August 13, 2025 at 7:56 PM
NEONATAL RESPIRATORY TRIALS IN SICK & PRETERM NEWBORN INFANTS With Professor Brett Manley, Consultant Neonatologist Mercy Hospital For Women, Melbourne & Professor of Neonatal Medicine Department of Obstetrics, Gynaecology and Newborn Health, University of Melbourne, Australia youtu.be/NAY_0xBGsrw
Read this!
Does counting ribs on neonatal CXR really work?
In 218 babies, we found a weak correlation with CT lung volumes.
Time to abandon old dogmas?
Lead by Dr Sophia Dahm published in @jama.com pediatrics.
@davidtingay1.bsky.social @nhmrc.bsky.social
jamanetwork.com/journals/jam...
In 218 babies, we found a weak correlation with CT lung volumes.
Time to abandon old dogmas?
Lead by Dr Sophia Dahm published in @jama.com pediatrics.
@davidtingay1.bsky.social @nhmrc.bsky.social
jamanetwork.com/journals/jam...
Diaphragm Position on Chest Radiograph to Estimate Lung Volumes in Neonates
This cross-sectional study investigates if use of diaphragm position relative to posterior ribs on the chest radiograph of neonates reliably estimates aerated lung volume.
jamanetwork.com
July 22, 2025 at 10:52 PM
Read this!
Reposted by Brett J. Manley 🤷🏼♂️
Delighted & honoured to be contributing to the iconic “Cool Topics in Neonatology 2025” at The Women’s Melbourne with great friends & colleagues!
@ebneo.bsky.social @drbretty.bsky.social @nnrdbase.bsky.social @europerinatal.bsky.social
www.thewomens.org.au/health-profe...
@ebneo.bsky.social @drbretty.bsky.social @nnrdbase.bsky.social @europerinatal.bsky.social
www.thewomens.org.au/health-profe...
Cool Topics in Neonatology 2025 | The Royal Women's Hospital
www.thewomens.org.au
June 24, 2025 at 9:53 PM
Delighted & honoured to be contributing to the iconic “Cool Topics in Neonatology 2025” at The Women’s Melbourne with great friends & colleagues!
@ebneo.bsky.social @drbretty.bsky.social @nnrdbase.bsky.social @europerinatal.bsky.social
www.thewomens.org.au/health-profe...
@ebneo.bsky.social @drbretty.bsky.social @nnrdbase.bsky.social @europerinatal.bsky.social
www.thewomens.org.au/health-profe...
Registration for Cool Topics in Neonatology 😎 November 2025 in Melbourne is NOW OPEN! #neosky
Anup Katheria!
Neena Modi!
Richard Martin!
TORPIDO 30/60 results!
Coconut oil trial (COSI-2) results!
AIROplane results (maybe)!
t.co/DwpA3rkUCi
Anup Katheria!
Neena Modi!
Richard Martin!
TORPIDO 30/60 results!
Coconut oil trial (COSI-2) results!
AIROplane results (maybe)!
t.co/DwpA3rkUCi
https://www.eventbrite.com.au/e/cool-topics-in-neonatology-2025-tickets-1393383139479?aff=oddtdtcreator
t.co
June 24, 2025 at 12:35 AM
Registration for Cool Topics in Neonatology 😎 November 2025 in Melbourne is NOW OPEN! #neosky
Anup Katheria!
Neena Modi!
Richard Martin!
TORPIDO 30/60 results!
Coconut oil trial (COSI-2) results!
AIROplane results (maybe)!
t.co/DwpA3rkUCi
Anup Katheria!
Neena Modi!
Richard Martin!
TORPIDO 30/60 results!
Coconut oil trial (COSI-2) results!
AIROplane results (maybe)!
t.co/DwpA3rkUCi
Thrilled to have Prof. Georg Schmölzer @research4babies.bsky.social presenting on resuscitation studies @mercyperinatal.bsky.social #neosky
April 11, 2025 at 3:11 AM
Thrilled to have Prof. Georg Schmölzer @research4babies.bsky.social presenting on resuscitation studies @mercyperinatal.bsky.social #neosky
Reposted by Brett J. Manley 🤷🏼♂️
The most recent AAP SONPM Journal Club webinar is available - youtu.be/beh82Mgor7Q
Dr. Aung (Neonatal-Perinatal Fellow, St. Christopher's Hospital) gave an excellent overview of the PLUSS trial. Thank you to @drbretty.bsky.social and Dr. Watterberg for joining! #neobluesky
Dr. Aung (Neonatal-Perinatal Fellow, St. Christopher's Hospital) gave an excellent overview of the PLUSS trial. Thank you to @drbretty.bsky.social and Dr. Watterberg for joining! #neobluesky
AAP SONPM Journal Club - March 19th, 2025 - PLUSS Trial
YouTube video by Neo TECaN
youtu.be
March 31, 2025 at 12:45 PM
The most recent AAP SONPM Journal Club webinar is available - youtu.be/beh82Mgor7Q
Dr. Aung (Neonatal-Perinatal Fellow, St. Christopher's Hospital) gave an excellent overview of the PLUSS trial. Thank you to @drbretty.bsky.social and Dr. Watterberg for joining! #neobluesky
Dr. Aung (Neonatal-Perinatal Fellow, St. Christopher's Hospital) gave an excellent overview of the PLUSS trial. Thank you to @drbretty.bsky.social and Dr. Watterberg for joining! #neobluesky
There’s a specific reason I have the idk 🤷🏼♂️ emoji in my profile
It’s because idk 🤷🏼♂️ a LOT of stuff, and openly admit that
We are playing catch up in neonatology because we have so many established practices that are not strongly based in evidence
#neosky
It’s because idk 🤷🏼♂️ a LOT of stuff, and openly admit that
We are playing catch up in neonatology because we have so many established practices that are not strongly based in evidence
#neosky
March 21, 2025 at 11:04 PM
There’s a specific reason I have the idk 🤷🏼♂️ emoji in my profile
It’s because idk 🤷🏼♂️ a LOT of stuff, and openly admit that
We are playing catch up in neonatology because we have so many established practices that are not strongly based in evidence
#neosky
It’s because idk 🤷🏼♂️ a LOT of stuff, and openly admit that
We are playing catch up in neonatology because we have so many established practices that are not strongly based in evidence
#neosky
Have you read our article about adaptive platform trials for preterm birth yet? #neosky
We discuss the challenges facing perinatal clinical researchers and how traditional RCTs may no longer be fit for purpose in our field.
Are APTs the answer?
www.thelancet.com/journals/lan...
We discuss the challenges facing perinatal clinical researchers and how traditional RCTs may no longer be fit for purpose in our field.
Are APTs the answer?
www.thelancet.com/journals/lan...
Adapt to survive and thrive: the time is now for adaptive platform trials for preterm birth
In this Viewpoint, we discuss the challenges facing perinatal clinical researchers,
many of which are unique to this field, and how traditional two-arm randomised trials
using frequentist analysis mig...
www.thelancet.com
March 20, 2025 at 9:54 PM
Have you read our article about adaptive platform trials for preterm birth yet? #neosky
We discuss the challenges facing perinatal clinical researchers and how traditional RCTs may no longer be fit for purpose in our field.
Are APTs the answer?
www.thelancet.com/journals/lan...
We discuss the challenges facing perinatal clinical researchers and how traditional RCTs may no longer be fit for purpose in our field.
Are APTs the answer?
www.thelancet.com/journals/lan...
Keith Barrington’s thoughts on @platipus.bsky.social #neosky
Is it a duck? Is it a mole? Platipus and Trial Design Innovations.
When the platypus was first captured, killed, skinned and the pelt sent to a zoologist in London, George Shaw in 1799, he thought he was being scammed. He tried to find the stitches that had been used to cobble together the…
When the platypus was first captured, killed, skinned and the pelt sent to a zoologist in London, George Shaw in 1799, he thought he was being scammed. He tried to find the stitches that had been used to cobble together the…
Is it a duck? Is it a mole? Platipus and Trial Design Innovations.
When the platypus was first captured, killed, skinned and the pelt sent to a zoologist in London, George Shaw in 1799, he thought he was being scammed. He tried to find the stitches that had been used to cobble together the specimen. Being unable to do so, he then concluded that it was probably real, and was unique. It was what we would now consider an evolutionary innovation, it had features of previous organisms, such as laying eggs, and several new features, being venomous and producing milk to feed their young, once they have hatched.
neonatalresearch.org
February 19, 2025 at 7:14 PM
Keith Barrington’s thoughts on @platipus.bsky.social #neosky
Save the dates for Cool Topics in Neonatology 😎
November 27-28, Melbourne 🇦🇺🦘
With:
⭐️ Anup Katheria 🇺🇸
⭐️ Neena Modi 🇬🇧
⭐️ Richard Martin 🇺🇸
… and many more!
Additional workshops and details to be announced in the coming months.
November 27-28, Melbourne 🇦🇺🦘
With:
⭐️ Anup Katheria 🇺🇸
⭐️ Neena Modi 🇬🇧
⭐️ Richard Martin 🇺🇸
… and many more!
Additional workshops and details to be announced in the coming months.
January 31, 2025 at 1:28 AM
Save the dates for Cool Topics in Neonatology 😎
November 27-28, Melbourne 🇦🇺🦘
With:
⭐️ Anup Katheria 🇺🇸
⭐️ Neena Modi 🇬🇧
⭐️ Richard Martin 🇺🇸
… and many more!
Additional workshops and details to be announced in the coming months.
November 27-28, Melbourne 🇦🇺🦘
With:
⭐️ Anup Katheria 🇺🇸
⭐️ Neena Modi 🇬🇧
⭐️ Richard Martin 🇺🇸
… and many more!
Additional workshops and details to be announced in the coming months.
So excited to share our commentary out now in LancetCAH and freely available via the link below!
The time is NOW for Adaptive Platform Trials to improve outcomes for preterm infants! @platipus.bsky.social
url.au.m.mimecastprotect.com/s/ukzLCmOxr6...
The time is NOW for Adaptive Platform Trials to improve outcomes for preterm infants! @platipus.bsky.social
url.au.m.mimecastprotect.com/s/ukzLCmOxr6...
url.au.m.mimecastprotect.com
January 23, 2025 at 12:24 AM
So excited to share our commentary out now in LancetCAH and freely available via the link below!
The time is NOW for Adaptive Platform Trials to improve outcomes for preterm infants! @platipus.bsky.social
url.au.m.mimecastprotect.com/s/ukzLCmOxr6...
The time is NOW for Adaptive Platform Trials to improve outcomes for preterm infants! @platipus.bsky.social
url.au.m.mimecastprotect.com/s/ukzLCmOxr6...
Reposted by Brett J. Manley 🤷🏼♂️
Attending #PAS2025?
Don't miss our workshop on Evaluating Trustworthiness: Identifying Spin, Fraud, and Deception in Modern Research
Date: Friday, April 25, 2025
Time: 4:00 PM - 5:30 PM
@ebneo.bsky.social
Rasheda Vereen @atulmalhotra.bsky.social @briankingneo.bsky.social @drabdulrazak.bsky.social
Don't miss our workshop on Evaluating Trustworthiness: Identifying Spin, Fraud, and Deception in Modern Research
Date: Friday, April 25, 2025
Time: 4:00 PM - 5:30 PM
@ebneo.bsky.social
Rasheda Vereen @atulmalhotra.bsky.social @briankingneo.bsky.social @drabdulrazak.bsky.social
January 21, 2025 at 9:57 AM
Attending #PAS2025?
Don't miss our workshop on Evaluating Trustworthiness: Identifying Spin, Fraud, and Deception in Modern Research
Date: Friday, April 25, 2025
Time: 4:00 PM - 5:30 PM
@ebneo.bsky.social
Rasheda Vereen @atulmalhotra.bsky.social @briankingneo.bsky.social @drabdulrazak.bsky.social
Don't miss our workshop on Evaluating Trustworthiness: Identifying Spin, Fraud, and Deception in Modern Research
Date: Friday, April 25, 2025
Time: 4:00 PM - 5:30 PM
@ebneo.bsky.social
Rasheda Vereen @atulmalhotra.bsky.social @briankingneo.bsky.social @drabdulrazak.bsky.social
In ÉCLAT, extubating extremely preterm infants to a CPAP of 10 (range 9-11 for 24 hrs) vs. 7 (range 6-8 for 24 hours) decreased extubation failure, without obvious safety issues.
PEEPophobes lament! 😪
PEEPophobes lament! 😪
Congrats to the ECLAT trial - voted the 2023 Impact Article of the Year!
How did this trial impact your practice?
Original pub: buff.ly/4fzwECw
#ebneoreviews: buff.ly/49IhYPm
Campaign review with @nicupodcast coming soon!
#neoebm #EBNeoImpact23 #neosky
How did this trial impact your practice?
Original pub: buff.ly/4fzwECw
#ebneoreviews: buff.ly/49IhYPm
Campaign review with @nicupodcast coming soon!
#neoebm #EBNeoImpact23 #neosky
January 8, 2025 at 11:19 AM
In ÉCLAT, extubating extremely preterm infants to a CPAP of 10 (range 9-11 for 24 hrs) vs. 7 (range 6-8 for 24 hours) decreased extubation failure, without obvious safety issues.
PEEPophobes lament! 😪
PEEPophobes lament! 😪
Reposted by Brett J. Manley 🤷🏼♂️
In this cohort study, Lipp et al compare neonatal outcomes & neurodevelopmental outcomes between extremely preterm infants(23–25 wks GA) managed with noninvasive respiratory support & those intubated during 30 min after birth buff.ly/3WuTe8L
#neosky #neoEBM #EBNEOalerts
#neosky #neoEBM #EBNEOalerts
January 5, 2025 at 6:51 PM
In this cohort study, Lipp et al compare neonatal outcomes & neurodevelopmental outcomes between extremely preterm infants(23–25 wks GA) managed with noninvasive respiratory support & those intubated during 30 min after birth buff.ly/3WuTe8L
#neosky #neoEBM #EBNEOalerts
#neosky #neoEBM #EBNEOalerts
Reposted by Brett J. Manley 🤷🏼♂️
In this multicenter RCT, Greenberg et al compare proportions of preterm infants who had apnea and other adverse events in the 48 hours after 2-month vaccinations vs after no vaccinations. buff.ly/423iztP @jama.com
#neosky #neoEBM #EBNEOalerts
#neosky #neoEBM #EBNEOalerts
January 7, 2025 at 1:04 PM
In this multicenter RCT, Greenberg et al compare proportions of preterm infants who had apnea and other adverse events in the 48 hours after 2-month vaccinations vs after no vaccinations. buff.ly/423iztP @jama.com
#neosky #neoEBM #EBNEOalerts
#neosky #neoEBM #EBNEOalerts
Reposted by Brett J. Manley 🤷🏼♂️
Congrats to the MATISSE & ECLAT trials - finalist in 2023 @ebneo.bsky.social Impact Article of the Year campaign! Consider both below & navigate to buff.ly/3R5JhMy on 12/31/24 to cast your final vote!
MATISSE: buff.ly/418aHni
ECLAT: buff.ly/4fzwECw
#neosky #neoEBM
MATISSE: buff.ly/418aHni
ECLAT: buff.ly/4fzwECw
#neosky #neoEBM
December 30, 2024 at 11:36 PM
Congrats to the MATISSE & ECLAT trials - finalist in 2023 @ebneo.bsky.social Impact Article of the Year campaign! Consider both below & navigate to buff.ly/3R5JhMy on 12/31/24 to cast your final vote!
MATISSE: buff.ly/418aHni
ECLAT: buff.ly/4fzwECw
#neosky #neoEBM
MATISSE: buff.ly/418aHni
ECLAT: buff.ly/4fzwECw
#neosky #neoEBM
ÉCLAT of course! 🥇
The Final Vote!!!
Select the 2023 @ebneo.bsky.social Impact Article of the Year! 👇
buff.ly/3R5JhMy
Which of these 2 great publications will have the most impact on neonatal care?
#EBNeoImpact23 #neoebm #neosky
Select the 2023 @ebneo.bsky.social Impact Article of the Year! 👇
buff.ly/3R5JhMy
Which of these 2 great publications will have the most impact on neonatal care?
#EBNeoImpact23 #neoebm #neosky
January 1, 2025 at 3:16 AM
ÉCLAT of course! 🥇
Reposted by Brett J. Manley 🤷🏼♂️
A very big day for our PhD student, and neonatal nurse, Anna Kidman today, as her PhD was conferred from The University of Melbourne.
Her PhD supervisors, @drbretty.bsky.social , Risha Bhatia, Prof Peter Davis and myself are very proud of her achievements, and congratulate her- Dr Anna Kidman.
Her PhD supervisors, @drbretty.bsky.social , Risha Bhatia, Prof Peter Davis and myself are very proud of her achievements, and congratulate her- Dr Anna Kidman.
December 17, 2024 at 8:02 AM
A very big day for our PhD student, and neonatal nurse, Anna Kidman today, as her PhD was conferred from The University of Melbourne.
Her PhD supervisors, @drbretty.bsky.social , Risha Bhatia, Prof Peter Davis and myself are very proud of her achievements, and congratulate her- Dr Anna Kidman.
Her PhD supervisors, @drbretty.bsky.social , Risha Bhatia, Prof Peter Davis and myself are very proud of her achievements, and congratulate her- Dr Anna Kidman.
Reposted by Brett J. Manley 🤷🏼♂️
December 10, 2024 at 12:49 PM
One for all the Adaptive Platform Trial enthusiasts out there!
Go on… Meet me at the A.P.T. 🎶
@platipus.bsky.social #MedSky #NeoSky #NICUSky
open.spotify.com/track/5vNRhk...
Go on… Meet me at the A.P.T. 🎶
@platipus.bsky.social #MedSky #NeoSky #NICUSky
open.spotify.com/track/5vNRhk...
APT.
open.spotify.com
December 9, 2024 at 8:39 PM
One for all the Adaptive Platform Trial enthusiasts out there!
Go on… Meet me at the A.P.T. 🎶
@platipus.bsky.social #MedSky #NeoSky #NICUSky
open.spotify.com/track/5vNRhk...
Go on… Meet me at the A.P.T. 🎶
@platipus.bsky.social #MedSky #NeoSky #NICUSky
open.spotify.com/track/5vNRhk...