Dora Čerina
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doracerina.bsky.social
Dora Čerina
@doracerina.bsky.social
31 followers 100 following 4 posts
PhD student at the Zychlinsky lab working on neutrophils vs bacteria 👩‍🔬
Max Planck for Infection Biology in Berlin, Germany
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Reposted by Dora Čerina
sfmpathogenesis.bsky.social
Uropathogenic E. coli uses a novel two-gene system, DanRI, to outsmart neutrophils by blocking NETs and ROS. Induced by host nucleosomes, DanRI boosts bacterial survival & persistence. A new twist in immune evasion!
✍️ @doracerina.bsky.social & coll.
📖 shorturl.at/cAj05
#MicroSky
June 12, 2025 at 11:38 AM
doracerina.bsky.social
We're excited to share our new preprint on bioRxiv! ✨

You can view it here: www.biorxiv.org/content/10.1...

See below for more information 👇
The main culprit behind urinary tract infections is a strain of E. coli known as UPEC. To survive in the body, UPEC has to evade our immune system, especially neutrophils, a type of immune cell that traps and kills bacteria using web-like structures called NETs. In our study, we discovered a previously unknown two-gene system in UPEC that we named DanRI (Defense against neutrophil Regulator and Inhibitor). This system is turned on by NETs and helps the bacteria block neutrophil attacks. Without DanRI, UPEC struggles to survive and persist during infections.
June 16, 2025 at 8:41 AM
Reposted by Dora Čerina
mpiib-berlin.mpg.de
🚨 Paper alert! Happy to share the new publication by the Zychlinsky Lab (@mpiib.bsky.social) and Torres Lab (@torreslab.bsky.social) with the succinct but effective title "Histone H1 kills MRSA".
You can find the paper here: www.cell.com/cell-reports...
Histone H1 kills MRSA
Marsman et al. detect histone H1 in MRSA in human abscesses and demonstrate that it kills MRSA under physiological conditions. They identify through selective evolution and a genome-wide screen that h...
www.cell.com
November 15, 2024 at 12:44 PM